Example questions by topic

Here are example questions grouped by common research tasks. You do not need to specify which server to use — your AI assistant will figure that out automatically.

Exploring a gene of interest

• “Tell me everything IMPC knows about the gene Bmp4.”
• “What phenotypes does knocking out Notch1 cause in mice?”
• “What is the human ortholog of mouse gene Lepr, and what phenotypes are associated with it?”
• “Are there any mouse models available for Arid1b? What phenotypes do they show?”
• “Show top 10 most cited IMPC publications about the gene Mecp2.”

Studying a disease

• “Which IMPC mouse models are relevant to Parkinson’s disease?”
• “Find genes associated with hearing loss in the IMPC database.”
• “What mouse phenotypes are most similar to Type 2 diabetes?”
• “What IMPC publications are related to cardiovascular disease models?”

Ordering research materials

• “What mice can I order for the gene Pax6?”
• “Show me all CRISPR products available for Akt2.”
• “Are there ES cell clones available for MGI:104874?”
• “What targeting vectors exist for Bmp4?”

Translating between species

• “What is the mouse equivalent of human gene BRCA1?”
• “Find human orthologs for mouse genes Tp53 and Brca2.”
• “I have a list of human genes: TP53, EGFR, BRCA1. What are their mouse orthologs?”

Understanding IMPC data

• “How many genes has IMPC phenotyped so far?”
• “What experimental procedures does IMPC use?”
• “How many publications are in the IMPC database?”
• “What types of images does IMPC collect?”