How We Generate Our Data

  • Targeting genes that haven’t been studied yet
  • Standardised production methods to knock out genes
  • Mutants and wildtype mice tested under the same phenotyping protocols

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Understanding Our Data

  • We generate our own data, it is not aggregated from publications
  • A constantly growing dataset; mice continually tested
  • Data from 19¬†IMPC phenotyping centres, in 11 countries

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About the IMPC Project

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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Latest Data Release

Data release 11 has now been published. The number of phenotyped mutant lines has reached 6,900, bringing the total number of phenotyped genes to 6,440.

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Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

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We’re systematically phenotyping new knockout mice every day

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IMPC Editorial: How The Deep Genome Project Could Change our Understanding of Disease and Transform Healthcare

New IMPC editorial in Genome Biology: leading experts outline how mouse genetics continues to hold a vital role in disease research and healthcare. Learn how The Deep Genome Project will transform biology, medicine and global health and how the IMPC has been “shining a powerful light” on the dark genome.

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How IMPC Experts are Categorically Analysing Gene Essentiality to Find New Possible Genetic Causes of Disease

New IMPC paper in Nature Communications: how IMPC researchers are using new FUSIL categorisation to find candidate genes associated with rare diseases – opening future research possibilities for solving undiagnosed disease cases.

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Our Collaborations

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Maintaining and expanding a world-wide consortium of institutions

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