How We Generate Our Data

  • Targeting genes that haven’t been studied yet
  • Standardised production methods to knock out genes
  • Mutants and wildtype mice tested under the same phenotyping protocols

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Understanding Our Data

  • We generate our own data, it is not aggregated from publications
  • A constantly growing dataset; mice continually tested
  • Data from 19 IMPC phenotyping centres, in 11 countries

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About the IMPC Project

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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Latest Data Release

Data release 10 has now been published. The number of phenotyped mutant lines has reached 6,255, bringing the total number of phenotyped genes to 5,861.

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Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

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We’re systematically phenotyping new knockout mice every day

IMPC Strategy 2021-2030

The IMPC’s 10-year strategy presents a bold ambition for the future functional annotation of the genome and deciphering genetic variation in the context of gene function and disease.

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Knockout Mouse Data Reveals Novel Genes Linked to Albinism and Other Oculocutaneous Conditions

A team of researchers have used IMPC data to identify novel genes associated with oculocutaneous syndromes in gene targeted ‘knockout’ mice, in research that is potentially relevant to human conditions such as albinism and phakomatoses.

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Maintaining and expanding a world-wide consortium of institutions

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