How We Generate Our Data
- Targeting genes that haven’t been studied yet
- Standardised production methods to knock out genes
- Mutants and wildtype mice tested under the same phenotyping protocols
Understanding Our Data
- We generate our own data, it is not aggregated from publications
- A constantly growing dataset; mice continually tested
- Data from 19 IMPC phenotyping centres, in 11 countries
About the IMPC Project
The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.
Latest Data Release
Data release 10 has now been published. The number of phenotyped mutant lines has reached 6,255, bringing the total number of phenotyped genes to 5,861.
Animal Welfare
The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.
IMPC Editorial: How The Deep Genome Project Could Change our Understanding of Disease and Transform Healthcare
New IMPC editorial in Genome Biology: leading experts outline how mouse genetics continues to hold a vital role in disease research and healthcare. Learn how The Deep Genome Project will transform biology, medicine and global health and how the IMPC has been “shining a powerful light” on the dark genome.
How IMPC Experts are Categorically Analysing Gene Essentiality to Find New Possible Genetic Causes of Disease
New IMPC paper in Nature Communications: how IMPC researchers are using new FUSIL categorisation to find candidate genes associated with rare diseases – opening future research possibilities for solving undiagnosed disease cases.
Maintaining and expanding a world-wide consortium of institutions
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