How We Generate Our Data

  • Targeting genes that haven’t been studied yet
  • Standardised production methods to knock out genes
  • Mutants and wildtype mice tested under the same phenotyping protocols

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Understanding Our Data

  • We generate our own data, it is not aggregated from publications
  • A constantly growing dataset; mice continually tested
  • Data from 19 IMPC phenotyping centres, in 11 countries

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About the IMPC Project

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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Latest Data Release

Data release 12 has now been published. The number of phenotyped mutant lines has reached 7,606, bringing the total number of phenotyped genes to 7,022.

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Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

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We’re systematically phenotyping new knockout mice every day

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We’ve Made Some Changes: FTP Server Update

Since Data Release 12.0, we’ve made some improvements to our FTP server. Read our update to find out what has changed.

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Researchers Investigate the Cause of Fam151b-related Retinal Degeneration

IMPC highlighted Fam151b as a gene of interest for retinal degeneration. Researchers from the MRC Human Genetics Unit, Mary Lyon Centre and Roslin Institute collaborated together to elucidate how Fam151b (and the paralogue Fam151a) could cause the resulting phenotype.

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Our Collaborations

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Maintaining and expanding a world-wide consortium of institutions

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