How We Generate Our Data

  • Targeting genes that haven’t been studied yet
  • Standardised production methods to knock out genes
  • Mutants and wildtype mice tested under the same phenotyping protocols

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Understanding Our Data

  • We generate our own data, it is not aggregated from publications
  • A constantly growing dataset; mice continually tested
  • Data from 19¬†IMPC phenotyping centres, in 11 countries

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About the IMPC Project

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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Latest Data Release

Data release 11 has now been published. The number of phenotyped mutant lines has reached 6,900, bringing the total number of phenotyped genes to 6,440.

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Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

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We’re systematically phenotyping new knockout mice every day

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IMPC COVID-19 Update

We know it’s vital that our users are kept up-to-date on IMPC’s status during the coronavirus outbreak. Read our update for the latest information on our resources and services.

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Antibody Proves Effective Against Leaky Channels Implicated in Rare Disease

Our consortium partners at CNR Monterotondo worked with researchers from ShanghaiTech University to test a relatively new anti-connexin antibody. Connexin (Cx) hemichannels have been implicated in a large range of rare diseases so finding an effective antibody to reduce Cx activity could be a vital therapy option.

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Our Collaborations

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Maintaining and expanding a world-wide consortium of institutions

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