How We Generate Our Data
- Targeting genes that haven’t been studied yet
- Standardised production methods to knock out genes
- Mutants and wildtype mice tested under the same phenotyping protocols
Understanding Our Data
- We generate our own data, it is not aggregated from publications
- A constantly growing dataset; mice continually tested
- Data from 19 IMPC phenotyping centres, in 11 countries
About the IMPC Project
The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.
Latest Data Release
Data release 11 has now been published. The number of phenotyped mutant lines has reached 6,900, bringing the total number of phenotyped genes to 6,440.
Animal Welfare
The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.
IMPC COVID-19 Update
We know it’s vital that our users are kept up-to-date on IMPC’s status during the coronavirus outbreak. Read our update for the latest information on our resources and services.
Steroid Biosynthesis Pathway Could Be Targeted to Reactivate Anti-tumour Immunity
A guest blog post by Bidesh Mahata, group leader in the Division of Immunology, Department of Pathology, University of Cambridge. His team studied a steroid biosynthesis pathway which tumour cells use to suppress the immune system. This pathway could be exploited to re-activate anti-tumour immunity. Find out how the IMPC contributed.
Maintaining and expanding a world-wide consortium of institutions
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