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IMPC's Data Generation and Phenotyping Process

How We Generate Our Data

Targeting genes that haven’t been studied yet
Standardised production methods to knock out genes
Mutants and wildtype mice tested under the same phenotyping protocols

IMPC's Phenotyping Pipeline Illustration

Understanding Our Data

We generate our own data, it is not aggregated from publications
A constantly growing dataset; mice continually tested
Data from 19 IMPC phenotyping centres, in 11 countries

The International Mouse Phenotyping Consortium (IMPC) is a global effort to identify the function of every protein-coding gene in the mouse genome. Our growing catalogue of mammalian gene function is freely available for researchers.

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Number of phenotyped genes

Latest Data Release

Data release 10 has now been published. The number of phenotyped mutant lines has reached 6,255, bringing the total number of phenotyped genes to 5,861.

Animal Welfare

The IMPC collects data from member institutes who collect phenotyping data guided by their own ethical review panels, licenses, and accrediting bodies that reflect the national and/or geo-political constructs in which they operate.

We’re systematically phenotyping new knockout mice every day

Horizon 2020 - Opportunities to Partner With The IMPC

Horizon 2020 is the biggest EU Research and Innovation programme ever. Funding opportunities under Horizon 2020 are set out in multi-annual work programmes – and the IMPC is currently looking for partners with which to submit funding applications under Societal Challenge 1 – Health, demographic change and wellbeing.

Large-Scale Study Uncovers 198 Genes Associated With Brain Morphogenesis in Mice

With a contribution from the IMPC, recent research, published in Nature Communications, has identified 198 genes associated with brain morphogenesis in mice – 83% of these constitute genes newly implicated in brain architecture.