Help & Documentation

Significant phenotypes, Measurement charts and All data tables

Data for each gene is organised in three tabs, “Significant phenotypes”, “Measurements chart” and “All data table”.

  • Significant phenotypes: phenotypes as identified by mutant mice being significantly different compared to wild type mice (the baseline). Phenotypes are indicated by Mammalian Phenotype (MP) Ontology terms as described in IMPReSS.

Example: the parameter “distance travelled” can be associated with one of three MP terms “abnormal locomotor activation”, “hyperactivity” or “hypoactivity”. 

The physiological system affected, the knockout allele, zygosity, sex, and the P-value for which the phenotype is detected are indicated. 

Note: significant associations are collapsed by MP term so that each phenotype can have several P-values associated with if separate analysis has been performed for different lines, different parameters and the sexe. Only the most significant association is shown in the table. 

By clicking on the row for the MP term, all charts for the significant associations are displayed.

  • Measurements chart: most significant result for each parameter (if separate analysis has been performed on different lines and sexes). Results can be filtered by physiological system (drop-down menu) and/or procedure (chart legend). Hovering over the points shows measurement-related information. Clicking on the points displays the underlying data by opening up the chart page.

All data: all data collected displaying data allele, centre and parameter. Results can be filtered by physiological system (drop-down menu) or by typing a keyword in the filter box provided (e.g., name of a procedure or a production center) to locate specific results.

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