Gene: Cib2

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Name
calcium and integrin binding family member 2
MGI ID
MGI:1929293
Synonyms
calcium binding protein Kip2 2810434I23Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating triglyceride level Cib2tm1b(EUCOMM)Wtsi HOM Early adult 6.78×10-05
abnormal startle reflex Cib2tm1b(EUCOMM)Wtsi HOM Early adult 2.74×10-20
abnormal auditory brainstem response Cib2tm1b(EUCOMM)Wtsi HOM   Early adult 2.80×10-05
increased circulating cholesterol level Cib2tm1b(EUCOMM)Wtsi HOM Early adult 2.69×10-05
decreased startle reflex Cib2tm1b(EUCOMM)Wtsi HOM Early adult 1.90×10-20
abnormal ear morphology Cib2tm1b(EUCOMM)Wtsi HOM Early adult 3.28×10-10
limb grasping Cib2tm1b(EUCOMM)Wtsi HOM Early adult 1.13×10-06
tremors Cib2tm1b(EUCOMM)Wtsi HOM Early adult 4.98×10-05
decreased prepulse inhibition Cib2tm1b(EUCOMM)Wtsi HOM   Early adult 9.51×10-07
increased circulating HDL cholesterol level Cib2tm1b(EUCOMM)Wtsi HOM Early adult 5.40×10-05

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (3/590) N/A
Aorta 3 No  (1/590) N/A
Bone 3 No N/A
Brain 3 No  (3/590)  (3/3)  Wholemount images
Brainstem 3 No  (2/590)  (2/3)  Wholemount images
Brown adipose tissue 3 No  (2/3)  Wholemount images
Cartilage tissue 3 No N/A
Cerebellum 3 No  (3/590) N/A
Cerebral cortex 3 No  (2/590)  (3/3)  Wholemount images
Esophagus 3 No  (7/415) N/A
Eye 3 No N/A
Gall bladder 3 No N/A
Heart 3 No  (1/590) N/A
Hippocampus 3 No  (3/590)  (3/3)  Wholemount images
Hypothalamus 3 No  (2/590)  (3/3)  Wholemount images
Kidney 3 No  (20/590) N/A
Large intestine 3 No  (10/590) N/A
Liver 3 No N/A
Lower urinary tract 3 No  (1/590) N/A
Lung 3 No  (1/590) N/A
Lymph node 3 No N/A
Mammary gland 3 No N/A
Olfactory lobe 3 No  (2/590)  (3/3)  Wholemount images
Oral epithelium 3 No N/A
Ovary 3 No  (1/590) N/A
Oviduct 3 No N/A
Pancreas 3 No  (5/590) N/A
Parathyroid gland 3 No  (2/3) N/A
Peripheral nervous system 3 No  (1/590) N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No  (1/590) N/A
Prostate gland 3 No  (12/590) N/A
Skeletal muscle 3 No N/A
Skin 3 No N/A
Small intestine 3 No  (9/590) N/A
Spinal cord 3 No  (2/590)  (2/3)  Wholemount images
Spleen 3 No  (2/590) N/A
Stomach 3 No  (13/590) N/A
Striatum 3 No  (3/590) N/A
Testis 3 No  (5/590)  (1/3)  Wholemount images
Thymus 3 No N/A
Thyroid gland 3 No  (16/590) N/A
Trachea 3 No  (2/590) N/A
Uterus 3 No N/A
Vascular system 3 No N/A
White adipose tissue 3 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3  (6/506)  (3/5) N/A
Ear 3  (1/506) N/A
Embryo 3  (1/507)  (4/5) N/A
Eye 3  (1/506)  (1/5) N/A
Foot 3  (1/506)  (3/5) N/A
Forebrain 3  (1/506)  (3/5) N/A
Forelimb 3  (1/506)  (3/5) N/A
Hand 3  (1/506)  (3/5) N/A
Head 3  (5/506)  (3/5) N/A
Heart 3  (1/506) N/A
Hindbrain 3  (6/506)  (3/5) N/A
Hindlimb 3  (1/506)  (3/5) N/A
Liver 3  (1/504) N/A
Lung 3  (1/504)  (1/5) N/A
Mandibular process 3  (1/506) N/A
Maxillary process 3  (1/506) N/A
Midbrain 3  (1/506)  (3/5) N/A
Oral cavity 3  (1/504) N/A
Skin 3  (1/506) N/A
Tail 3  (1/506) N/A
Tail somite 3  (1/506) N/A

 Associated Images

Echo: M-Mode Images
79 Images
X-ray: XRay Images Whole Body Lateral Orientation
21 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
32 Images
X-ray: XRay Images Hind Leg and Hip
12 Images
Adult LacZ: LacZ Images Wholemount
7 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
3 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cib2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cib2tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice
Cib2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Cib2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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