What can I use the IMPC data for?
The data the IMPC is collecting allows to identify the physiological systems that are disrupted when a gene is disabled, in order to make gene-phenotype associations. In particular, the IMPC focuses on those genes about which nothing is known, the ‘ignorome’. Thus, IMPC data can be used towards increasing our understanding of gene function and to identify models of human disease based on phenotypic similarity scores. Disease models allow researchers to investigate molecular mechanisms underlying human genetic diseases and explore new therapeutic interventions. In addition to translating knowledge from mouse to human, the translation to other species, including domestic and wild species, is relevant as well.