Genes Phenotypes

Researchers Investigate the Cause of Fam151b-related Retinal Degeneration

Researchers at the MRC Human Genetics Unit (Institute for Genetics and Molecular Medicine, University of Edinburgh) collaborated with the Mary…

Published: 12 Oct 2020

Steroid Biosynthesis Pathway Could Be Targeted to Reactivate Anti-tumour Immunity

Guest blog post by Bidesh Mahata. Bidesh Mahata is a newly recruited group leader in the Division of Immunology, Department…

Published: 17 Jul 2020

Gene Found for BCAA Clearance in Brown Fat Protects Against Obesity & Diabetes

Branched-chain amino acids (BCAAs) are amino acids that have a central carbon atom with a branch of three or more…

Published: 25 Jun 2020

Researchers Study Biomarker Patterns to Define the Start of Ageing

Scientists worldwide are still attempting to define ageing and mortality through research. Debate on ageing continues to vary widely and…

Published: 19 May 2020

Arf1-KO Induces Anti-Tumour Response with Protective Vaccination

A study investigating the role of Arf1 shows promising results for new therapeutic strategies involving DAMP-mediated anti-tumour immunity to target…

Published: 27 Apr 2020

Brain (correct size)

Study Uncovers 198 Genes Associated With Brain Morphogenesis in Mice

With a contribution from the IMPC, recent research, published in Nature Communications, has identified 198 genes associated with brain morphogenesis…

Published: 4 Oct 2019

Knockout Mouse Model Reveals Insight into Traits Associated With PCD

Members of the IMPC Consortium at CNR-Monterotondo (Italy) have used embryonic stem (ES) cells produced as part of the IMPC…

Published: 16 Aug 2019

PIK3CA inhibition with BYL719 – a novel treatment for CLOVES syndrome

CLOVES syndrome is a rare condition that is characterised by tissue overgrowth and vascular abnormalities, caused by mosaic gain-of-function mutations…

Published: 3 Jul 2019

SETD3 – An Actin Methyltransferase That Prevents Primary Dystocia

Research published in Nature identifies SET domain protein 3 (SETD3) as a physiological actin methyltransferase, and uncovers SETD3’s crucial role…

Published: 20 May 2019

Research Reveals Novel Genetic Influences On Osteoporosis

Recent research, published in nature genetics, identifies novel genetic influences on osteoporosis, with the potential to empower future research on…

Published: 19 Mar 2019

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