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Accessing the Data

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Software

Latest IMPC Papers
Data Supporting IMPC Papers

Pain Sensitivity Associated Genes

Essential Genes - Linking to Disease

Essential Genes - Translating to Other Species

Sexual Dimorphism

Genes Critical for Hearing Identified

Genetic Basis for Metabolic Diseases

Papers Using IMPC Resources

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Genes Phenotypes Help, News, Blog
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The development of a potential treatment for alkaptonuria shows the utility of mouse models in the study of rare diseases

The inhibition of alkaptonuria by the chemical nitisinone in a mouse model led to a full-scale clinical trial funded by…

Published: 22 Feb 2019

Using machine learning to identify mammalian essential genes

By Kathryn Hentges and Andrew Doig Essential genes are those that are required for an organism to survive. We have…

Published: 20 Feb 2019

Gene editing possible for kidney disease

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave…

Published: 19 Nov 2018

RERE deficiency leads to downregulation of Gata4 and the development of ventricular septal defects

ASHG 2018 Annual Meeting – research using mouse models Guest post by Bum-Jun Kim (ASHG talk: Wednesday, 4:30pm - 4:45pm in…

Published: 17 Oct 2018

Leveraging human and mouse genetics to identify novel bone genes

ASHG 2018 Annual Meeting - research using mouse models Guest post by John Morris (ASHG talk: Wed Oct 17, 9:00am - 9:15am…

Published: 11 Oct 2018

A single gene mutation may have helped humans become optimal long-distance runners

In novel study, mice engineered to lack the same gene run stronger, longer and with less fatigue Two to three…

Published: 12 Sep 2018

Researchers block RNA silencing protein in liver to prevent obesity and diabetes in mice

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but…

Published: 12 Sep 2018

Insights into eyesight – discovery of retina regulatory molecules

15 novel genes related to retinal function have been found in research published by Dr. Melanie Samuel and colleagues in…

Published: 6 Sep 2018

Researchers outline game-theory approach to better understand genetics

Principles of game theory offer new ways of understanding genetic behavior, a pair of researchers has concluded in a new…

Published: 5 Sep 2018

New research sheds light on the relationship between genes and bone fracture risk

An article published in the British Medical Journal reports findings from a large international collaboration that identified 15 variations in…

Published: 5 Sep 2018

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