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How Does The IMPC Contribute To Rare Disease Research?

Jump to: What is Rare Disease?Why are Mice Important?Who We Are and What We DoHow Has The IMPC Contributed to…

Published: 27 Feb 2021

CRISPR is an extremely useful tool for mouse models but is not ready for use on human embryos

A researcher in China claims to have produced the first genome-edited babies through using CRISPR. The IMPC uses the CRISPR/Cas9…

Published: 28 Nov 2018

Mouse study identifies new target for human accelerated aging syndrome

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome…

Published: 3 Jul 2018

Functional genes in dilated cardiomyopathy

https://www.youtube.com/watch?v=vriEwZi5QOU Nishanth Ulhas Nair discusses his recent article in Scientific Reports: Putative functional genes in idiopathic dilated cardiomyopathy Link to…

Published: 11 Jun 2018

New research suggests laboratory mouse data can help in wildlife conservation

The International Mouse Phenotyping Consortium (IMPC) has been predominantly interested in using mouse models to understand human health and disease.…

Published: 25 May 2018

Human gene essentiality

  https://www.youtube.com/watch?v=7YnUAHhGGcg   Amalio Telenti discusses his recent article in Nature: Human gene essentiality Link to article: https://www.nature.com/articles/nrg.2017.75.pdf  More information on…

Published: 25 May 2018

What makes us unique? Exploring the role of genetics and neural function

[embed]https://www.youtube.com/watch?v=plytOIRhkiQ&t=9s[/embed] Melanie Samuel discusses her research in neural development and disease, and explains how she has used IMPC data. Melanie's…

Published: 20 Apr 2018

Estimating probability of phenotypically detectable protein damage

[embed]https://www.youtube.com/watch?v=LU7gUyp_fT0&t=23s[/embed] Dr. Tao Wang talks about his recent Nature Communications publication, in which he leverages the IMPC and Mutagenetix data…

Published: 7 Apr 2018

Early mammalian development and epigenetic regulation of genomes

[embed]https://www.youtube.com/watch?v=tcarxg0qb78&t=25s[/embed] Jesse Mager discusses his work in mammalian developmental genetics, and how he uses IMPC data for this research. More…

Published: 5 Apr 2018

New diabetes genes discovered in latest IMPC research

Scientists have identified a network of genes that could play an important role in the development of metabolic diseases such…

Published: 5 Apr 2018

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