Gene: Nr6a1

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Name
nuclear receptor subfamily 6, group A, member 1
MGI ID
MGI:1352459
Synonyms
NCNF Gcnf 1700113M01Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal somite shape Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal optic vesicle formation Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal heart morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal pericardium morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
preweaning lethality, complete penetrance Nr6a1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Nr6a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal tail bud morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal embryo development Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
decreased body length Nr6a1 HET Early adult 1.38×10-11
abnormal chorioallantoic fusion Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal forebrain development Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
persistence of hyaloid vascular system Nr6a1tm1b(EUCOMM)Wtsi HET Early adult 3.77×10-05
abnormal embryo size Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal embryo turning Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal visceral yolk sac morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal neural tube closure Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal allantois morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
embryonic growth retardation Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal heart looping Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal neural tube morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal pharyngeal arch morphology Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
pale yolk sac Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal midbrain development Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
abnormal hindbrain development Nr6a1tm1b(EUCOMM)Wtsi HOM E9.5 0.00
increased startle reflex Nr6a1 HET Early adult 8.45×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2)  Wholemount images
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/388)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57)  (2/2) N/A
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 2  (6/504)  (2/2) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Cranium 2  (1/61)  (2/2) N/A
Dorsal root ganglion 2  (1/57)  (2/2) N/A
Ear 2  (1/504)  (2/2) N/A
Embryo 2  (1/505)  (2/2) N/A
Outer ear 2  (1/66)  (2/2) N/A
Eye 2  (1/504)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/52)  (2/2) N/A
Foot 2  (1/504)  (2/2) N/A
Forearm 2  (1/297)  (2/2) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58)  (2/2) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Head mesenchyme 2  (1/57)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Heart ventricle 2  (1/57)  (2/2) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/61)  (2/2) N/A
Inner ear 2  (1/61)  (2/2) N/A
Intestine 2  (1/55)  (2/2) N/A
Liver 2  (1/504)  (2/2) N/A
Lower leg 2  (1/297)  (2/2) N/A
Lung 2  (1/500)  (2/2) N/A
Mandibular process 2  (1/504)  (2/2) N/A
Maxillary process 2  (1/504)  (2/2) N/A
Mesonephros of female 2  (1/52)  (2/2) N/A
Mesonephros of male 2  (1/52)  (2/2) N/A
Metanephros 2  (1/52)  (2/2) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nasal septum 2  (1/57)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Notochord 2  (1/57)  (2/2) N/A
Oral cavity 2  (1/504)  (2/2) N/A
Outflow tract 2  (1/57)  (2/2) N/A
Pancreas 2  (1/52)  (2/2) N/A
Pericardium 2  (1/52)  (2/2) N/A
Pharynx 2  (1/52)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/61)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/54)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 2  (1/504)  (2/2) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Stomach 2  (1/52)  (2/2) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/52)  (2/2) N/A
Tongue 2  (1/52)  (2/2) N/A
Trachea 2  (1/56)  (2/2) N/A
Trunk mesenchyme 2  (1/57)  (2/2) N/A
Umbilical artery embryonic part 2  (1/57)  (2/2) N/A
Umbilical vein embryonic part 2  (1/57)  (2/2) N/A
Upper arm 2  (1/297)  (2/2) N/A
Upper leg 2  (1/297)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A
Vibrissa 2  (1/66)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
17 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nr6a1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nr6a1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Nr6a1tm47175(L1L2_gt0) Targeting vectors

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