Gene: Nr6a1

Name
nuclear receptor subfamily 6, group A, member 1
MGI ID
MGI:1352459
Synonyms
NCNF Gcnf 1700113M01Rik
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal hindbrain development Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal midbrain development Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal somite shape Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal tail bud morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 12.5 0.00
preweaning lethality, complete penetrance Nr6a1tm1b(EUCOMM)Wtsi HOM n/a 0.00
abnormal embryo turning Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal heart morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
decreased body length Nr6a1 HET postnatal 1.38×10-11
abnormal optic vesicle formation Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal pericardium morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal embryo size Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal visceral yolk sac morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal neural tube closure Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal allantois morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal heart looping Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal pharyngeal arch morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal embryo development Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal chorioallantoic fusion Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal neural tube morphology Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal forebrain development Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
decreased body weight Nr6a1 HET postnatal 1.09×10-06
persistence of hyaloid vascular system Nr6a1tm1b(EUCOMM)Wtsi HET postnatal 3.67×10-05
pale yolk sac Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
increased startle reflex Nr6a1 HET postnatal 8.45×10-05
embryonic growth retardation Nr6a1tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/383) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2)  Wholemount images
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/388)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/47)  (2/2) N/A
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 2  (6/485)  (2/2) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Cranium 2  (1/46)  (2/2) N/A
Dorsal root ganglion 2  (1/47)  (2/2) N/A
Ear 2  (1/485)  (2/2) N/A
Embryo 2  (1/485)  (2/2) N/A
Outer ear 2  (1/47)  (2/2) N/A
Eye 2  (1/485)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/46)  (2/2) N/A
Foot 2  (1/485)  (2/2) N/A
Forearm 2  (1/282)  (2/2) N/A
Forebrain 2  (1/485)  (2/2) N/A
Forelimb 2  (1/485)  (2/2) N/A
Fronto-nasal process 2  (1/48)  (2/2) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 2  (1/485)  (2/2) N/A
Head 2  (5/485)  (2/2) N/A
Head mesenchyme 2  (1/47)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Heart ventricle 2  (1/47)  (2/2) N/A
Hindbrain 2  (6/485)  (2/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/46)  (2/2) N/A
Inner ear 2  (1/46)  (2/2) N/A
Intestine 2  (1/47)  (2/2) N/A
Liver 2  (1/485)  (2/2) N/A
Lower leg 2  (1/282)  (2/2) N/A
Lung 2  (1/485)  (2/2) N/A
Mandibular process 2  (1/485)  (2/2) N/A
Maxillary process 2  (1/485)  (2/2) N/A
Mesonephros of female 2  (1/46)  (2/2) N/A
Mesonephros of male 2  (1/46)  (2/2) N/A
Metanephros 2  (1/46)  (2/2) N/A
Midbrain 2  (1/485)  (2/2) N/A
Nasal septum 2  (1/47)  (2/2) N/A
Nose 2  (1/51)  (2/2) N/A
Notochord 2  (1/47)  (2/2) N/A
Oral cavity 2  (1/485)  (2/2) N/A
Outflow tract 2  (1/47)  (2/2) N/A
Pancreas 2  (1/46)  (2/2) N/A
Pericardium 2  (1/46)  (2/2) N/A
Pharynx 2  (1/46)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/46)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/46)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 2  (1/485)  (2/2) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Stomach 2  (1/46)  (2/2) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/46)  (2/2) N/A
Tongue 2  (1/46)  (2/2) N/A
Trachea 2  (1/50)  (2/2) N/A
Trunk mesenchyme 2  (1/47)  (2/2) N/A
Umbilical artery embryonic part 2  (1/47)  (2/2) N/A
Umbilical vein embryonic part 2  (1/47)  (2/2) N/A
Upper arm 2  (1/282)  (2/2) N/A
Upper leg 2  (1/282)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A
Vibrissa 2  (1/47)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
4 Images
Adult LacZ: LacZ Images Wholemount
17 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nr6a1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nr6a1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Nr6a1tm47175(L1L2_gt0) Targeting vectors

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