Genes Phenotypes

Researchers Investigate the Cause of Fam151b-related Retinal Degeneration

Researchers at the MRC Human Genetics Unit (Institute for Genetics and Molecular Medicine, University of Edinburgh) collaborated with the Mary…

Published: 12 Oct 2020

Steroid Biosynthesis Pathway Could Be Targeted to Reactivate Anti-tumour Immunity

Guest blog post by Bidesh Mahata. Bidesh Mahata is a newly recruited group leader in the Division of Immunology, Department…

Published: 17 Jul 2020

Computer generated SARS-CoV-2 virions.

SARS-CoV-2 and Mouse Genetics

What is SARS-CoV-2 and How Can Mice Help? Viruses are infective agents that cause disease. They are different from other…

Published: 2 Apr 2020

Using Exomiser for rare disease variant interpretation at scale in the 100,000 Genomes Project

ASHG 2018 Annual Meeting – research using mouse models Damian Smedley will give a talk on Wednesday from 9:30am to…

Published: 17 Oct 2018

Inhibiting NF-κB improves heart function in a mouse model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a devastating genetic disease that impairs cardiac and skeletal muscle development. People with DMD gradually…

Published: 4 Sep 2018

Researchers reverse aging-associated skin wrinkles and hair loss in a mouse model

A gene mutation causes wrinkled skin and hair loss; turning off that mutation restores the mouse to normal appearance. Wrinkled…

Published: 1 Aug 2018

The secret to building a strong heart lies in blood vessels

Research using IMPC resources offers new insight into congenital heart disease and may allow new therapies to be developed for human…

Published: 9 Jul 2018

NAD+ and the link between glucose and obesity

Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much…

Published: 27 Jun 2018

European Society of Human Genetics conference 2018

We are excited to be attending the European Society of Human Genetics (ESHG) 2018 conference this weekend in Milan! Visit stand…

Published: 11 Jun 2018

Human gene essentiality

  https://www.youtube.com/watch?v=7YnUAHhGGcg   Amalio Telenti discusses his recent article in Nature: Human gene essentiality Link to article: https://www.nature.com/articles/nrg.2017.75.pdf  More information on…

Published: 25 May 2018

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