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About the IMPC Institutional Members Corporate Associates Collaborations Funding Animal Welfare About KOMP Awards of Excellence
Training & Workshops

Workshops

Training

Getting Started with IMPC Data

IMPC Data Generation

How to Use Gene Pages

Citing IMPC Data

Allele design

IMPC Data Collections

Late Adult Data

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Cardiovascular

Accessing the Data

Latest Data Release

Access via API

Access via FTP

Batch query

Advanced Tools

Disease Models

PhenoDCC Tools

GenTaR

OpenStats

IMPReSS

Embryo Viewer

Software

Latest IMPC Papers
Data Supporting IMPC Papers

Pain Sensitivity Associated Genes

Essential Genes - Linking to Disease

Essential Genes - Translating to Other Species

Sexual Dimorphism

Genes Critical for Hearing Identified

Genetic Basis for Metabolic Diseases

Papers Using IMPC Resources
Genes Phenotypes Help, News, Blog
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Knockout Mouse Model Reveals Insight into Traits Associated With PCD

Members of the IMPC Consortium at CNR-Monterotondo (Italy) have used embryonic stem (ES) cells produced as part of the IMPC…

Published: 16 Aug 2019

MRC: Rodent little brother project poster. Visit bit.ly/secretlivesofmice for more information

Can the Public Revolutionise How Mouse Models Are Studied?

In collaboration with NC3Rs, IMPC member institution MRC Harwell has launched a new citizen science project that aims to advance…

Published: 24 Jul 2019

PIK3CA inhibition with BYL719 – a novel treatment for CLOVES syndrome

CLOVES syndrome is a rare condition that is characterised by tissue overgrowth and vascular abnormalities, caused by mosaic gain-of-function mutations…

Published: 3 Jul 2019

SETD3 – An Actin Methyltransferase That Prevents Primary Dystocia

Research published in Nature identifies SET domain protein 3 (SETD3) as a physiological actin methyltransferase, and uncovers SETD3’s crucial role…

Published: 20 May 2019

Research Reveals Novel Genetic Influences On Osteoporosis

Recent research, published in nature genetics, identifies novel genetic influences on osteoporosis, with the potential to empower future research on…

Published: 19 Mar 2019

The development of a potential treatment for alkaptonuria shows the utility of mouse models in the study of rare diseases

The inhibition of alkaptonuria by the chemical nitisinone in a mouse model led to a full-scale clinical trial funded by…

Published: 22 Feb 2019

Using machine learning to identify mammalian essential genes

By Kathryn Hentges and Andrew Doig Essential genes are those that are required for an organism to survive. We have…

Published: 20 Feb 2019

CRISPR is an extremely useful tool for mouse models but is not ready for use on human embryos

A researcher in China claims to have produced the first genome-edited babies through using CRISPR. The IMPC uses the CRISPR/Cas9…

Published: 28 Nov 2018

Gene editing possible for kidney disease

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave…

Published: 19 Nov 2018

Genetic Variations in the Mouse

Gary Churchill discusses genetic variations in the mouse and how this variety can be used as a tool for understanding…

Published: 16 Nov 2018

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