Genes Phenotypes

Phenotype: increased heart rate

Definition
greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute
Synonyms
tachycardia
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased heart rate

Total number of significant genotype-phenotype associations: 66

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Gnb2
Gnb2em1(IMPC)J 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 5.56×10-09
Rrad
Rradtm1.1(KOMP)Vlcg 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.14×10-08
Klhl29
Klhl29tm1b(EUCOMM)Hmgu 		HOM Early adult increased heart rate Echo | HR ICS | IMPC 1.51×10-08
Rrad
Rradtm1.1(KOMP)Vlcg 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 2.10×10-08
Gnb2
Gnb2em1(IMPC)J 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.31×10-08
Fam161a
Fam161atm1b(KOMP)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.52×10-08
Adprm
Adprmtm1b(EUCOMM)Hmgu 		HOM Early adult increased heart rate Echo | HR HMGU | IMPC 1.52×10-07
Fam161a
Fam161atm1b(KOMP)Wtsi 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 2.25×10-07
Prkab1
Prkab1tm1b(KOMP)Wtsi 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR CCP-IMG | IMPC 4.09×10-07
Fsd2
Fsd2em1(IMPC)Mbp 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 4.23×10-07
Prkab1
Prkab1tm1b(KOMP)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR CCP-IMG | IMPC 4.53×10-07
Mbd5
Mbd5tm1b(EUCOMM)Wtsi 		HET Early adult shortened RR interval Electrocardiogram (ECG) | RR ICS | IMPC 1.05×10-06
Fsd2
Fsd2em1(IMPC)Mbp 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.70×10-06
Hunk
Hunktm1b(EUCOMM)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 3.40×10-06
Far2
Far2tm2b(KOMP)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.63×10-06
Zfp395
Zfp395tm1b(EUCOMM)Wtsi 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR BCM | IMPC 6.29×10-06
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu 		HOM Early adult increased heart rate Echo | HR MRC Harwell | IMPC 8.46×10-06
Il18r1
Il18r1em1(IMPC)Mbp 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 8.55×10-06
Zfp395
Zfp395tm1b(EUCOMM)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 9.31×10-06
Bzw2
Bzw2tm1b(KOMP)Mbp 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.68×10-05
Far2
Far2tm2b(KOMP)Wtsi 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.72×10-05
Rundc3a
Rundc3atm1b(EUCOMM)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 1.86×10-05
Phf19
Phf19tm1.1(KOMP)Vlcg 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.35×10-05
Trip13
Trip13tm1.1(KOMP)Vlcg 		HET Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.37×10-05
Sun1
Sun1tm1b(EUCOMM)Wtsi 		HOM Early adult increased heart rate Echo | HR ICS | IMPC 3.09×10-05
Lin28b
Lin28btm1b(EUCOMM)Hmgu 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.82×10-05
Sorbs2
Sorbs2tm1.1(KOMP)Mbp 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 4.18×10-05
Hspb1
Hspb1tm1.1(KOMP)Vlcg 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.29×10-05
Rec8
Rec8tm1b(KOMP)Wtsi 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.43×10-05
Ap3s1
Ap3s1tm1b(EUCOMM)Hmgu 		HOM Early adult increased heart rate Echo | HR HMGU | IMPC 4.50×10-05
Il2ra
Il2ratm1b(EUCOMM)Wtsi 		HOM Early adult increased heart rate Echo | HR ICS | IMPC 4.81×10-05
Phf19
Phf19tm1.1(KOMP)Vlcg 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 5.08×10-05
H1f10
H1f10tm1.1(KOMP)Vlcg 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.70×10-05
C9
C9tm1.1(KOMP)Vlcg 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.16×10-05
Pitx3
Pitx3tm1.1(KOMP)Vlcg 		HOM Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 6.27×10-05
Trip13
Trip13tm1.1(KOMP)Vlcg 		HET Early adult increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 7.50×10-05
Vsig8
Vsig8tm1.1(KOMP)Mbp 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 7.82×10-05
Nkg7
Nkg7tm1.1(KOMP)Vlcg 		HOM Early adult shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 7.95×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo
Electrocardiogram (ECG)
Non-Invasive blood pressure

 Phenotype associations stats

0.66% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart rate (29/4392)

0.57% females (25/4371) 0.60% males (25/4199)

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