MP:0002626 (increased heart rate) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Genes Phenotypes

Phenotype: increased heart rate

Definition

greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute

Synonyms

tachycardia

Significant gene associations The way we measure Phenotype stats

of tested genes

significant genes

tested genes

IMPC Gene variants with increased heart rate

Total number of significant genotype-phenotype associations: 157

Gene / Allele	Zygosity	Life Stage	Phenotype	Procedure \| Parameter	Phenotyping Center \| Source	P Value
Gnb2 Gnb2^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	3.99×10^-14
Gnb2 Gnb2^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.96×10^-13
Rrad Rrad^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	7.58×10^-12
Rrad Rrad^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.33×10^-11
Far2 Far2^{tm2b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.68×10^-09
Fam161a Fam161a^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	3.00×10^-09
Wdr6 Wdr6^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	7.43×10^-09
Fam161a Fam161a^{tm1b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	7.82×10^-09
Far2 Far2^{tm2b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	8.01×10^-09
Klhl29 Klhl29^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Echo \| HR	ICS \| IMPC	1.83×10^-08
Phf19 Phf19^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	1.90×10^-08
Ppp2r2b Ppp2r2b^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	TCP \| IMPC	4.14×10^-08
Sun1 Sun1^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	increased heart rate	Echo \| HR	ICS \| IMPC	5.73×10^-08
Phf19 Phf19^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	7.51×10^-08
Ppp2r2b Ppp2r2b^{tm1b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	TCP \| IMPC	8.36×10^-08
Wdr6 Wdr6^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.05×10^-07
Mbd5 Mbd5^{tm1b(EUCOMM)Wtsi}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	ICS \| IMPC	1.09×10^-07
H1f10 H1f10^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.46×10^-07
D5Ertd579e D5Ertd579e^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.46×10^-07
Adprm Adprm^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Echo \| HR	HMGU \| IMPC	2.21×10^-07
Nkg7 Nkg7^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	2.70×10^-07
Pacsin2 Pacsin2^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	3.13×10^-07
Esd Esd^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	3.59×10^-07
D5Ertd579e D5Ertd579e^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	4.04×10^-07
Hspb1 Hspb1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	4.09×10^-07
Ppfia3 Ppfia3^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	4.88×10^-07
Ppp1r9b Ppp1r9b^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	6.51×10^-07
Cbln3 Cbln3^{tm1.1(KOMP)Vlcg}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	7.12×10^-07
Vsig8 Vsig8^{tm1.1(KOMP)Mbp}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	7.48×10^-07
C9 C9^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	8.89×10^-07
Clcnkb Clcnkb^em1(IMPC)Mbp	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	8.91×10^-07
Trip13 Trip13^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	9.31×10^-07
Pja2 Pja2^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	BCM \| IMPC	9.73×10^-07
Nkg7 Nkg7^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	1.07×10^-06
Ppfia3 Ppfia3^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.15×10^-06
Hspb1 Hspb1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.23×10^-06
Wnk2 Wnk2^em1Murr	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.48×10^-06
Paqr6 Paqr6^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	BCM \| IMPC	1.54×10^-06
Mbd5 Mbd5^{tm1b(EUCOMM)Wtsi}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	ICS \| IMPC	1.68×10^-06
H1f10 H1f10^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.73×10^-06
Lin28b Lin28b^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.91×10^-06
Lin28b Lin28b^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.08×10^-06
Rbm22 Rbm22^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.08×10^-06
Sorbs2 Sorbs2^{tm1.1(KOMP)Mbp}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.09×10^-06
Ppp1r9b Ppp1r9b^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.10×10^-06
Cbln3 Cbln3^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.22×10^-06
Rbm22 Rbm22^{tm1.1(KOMP)Vlcg}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.40×10^-06
Esd Esd^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.67×10^-06
Cnnm2 Cnnm2^{tm1.1(KOMP)Vlcg}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	3.02×10^-06
Zfp275 Zfp275^{tm1.1(NCOM)Mfgc}	HEM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	TCP \| IMPC	3.30×10^-06
Crx Crx^{em1(IMPC)Ccpcz}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	CCP-IMG \| IMPC	3.39×10^-06
Clcnkb Clcnkb^em1(IMPC)Mbp	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	3.47×10^-06
Rec8 Rec8^{tm1b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	3.62×10^-06
Slc44a1 Slc44a1^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Echo \| HR	BCM \| IMPC	3.81×10^-06
Vsig8 Vsig8^{tm1.1(KOMP)Mbp}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	3.98×10^-06
Pacsin2 Pacsin2^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	3.99×10^-06
Synrg Synrg^{tm1b(EUCOMM)Wtsi}	HET	Early adult	increased heart rate	Echo \| HR	BCM \| IMPC	4.08×10^-06
Rundc3a Rundc3a^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	BCM \| IMPC	4.76×10^-06
Zfp395 Zfp395^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	BCM \| IMPC	4.87×10^-06
Il2ra Il2ra^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	increased heart rate	Echo \| HR	ICS \| IMPC	4.96×10^-06
C9 C9^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	5.45×10^-06
Nox4 Nox4^em1(IMPC)Mbp	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	5.67×10^-06
Dock11 Dock11^{tm2b(KOMP)Wtsi}	HEM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	6.58×10^-06
Ap3s1 Ap3s1^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Echo \| HR	HMGU \| IMPC	6.60×10^-06
Ccdc30 Ccdc30^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	7.13×10^-06
Nox4 Nox4^em1(IMPC)Mbp	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	7.55×10^-06
Wnk2 Wnk2^em1Murr	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	8.29×10^-06
Zfp275 Zfp275^{tm1.1(NCOM)Mfgc}	HEM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	TCP \| IMPC	8.38×10^-06
Zfp395 Zfp395^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	BCM \| IMPC	8.45×10^-06
Vsig4 Vsig4^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	8.93×10^-06
Leprotl1 Leprotl1^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Echo \| HR	MRC Harwell \| IMPC	9.29×10^-06
Crx Crx^{em1(IMPC)Ccpcz}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	CCP-IMG \| IMPC	9.47×10^-06
Hunk Hunk^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	HMGU \| IMPC	9.69×10^-06
Fuca1 Fuca1^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.02×10^-05
Trip13 Trip13^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.14×10^-05
Prkab1 Prkab1^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	1.17×10^-05
Pja2 Pja2^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	BCM \| IMPC	1.18×10^-05
Cyp4f14 Cyp4f14^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	HMGU \| IMPC	1.28×10^-05
Nmral1 Nmral1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	1.33×10^-05
Cldn19 Cldn19^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.47×10^-05
Setd3 Setd3^{tm1.1(NCOM)Mfgc}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	TCP \| IMPC	1.51×10^-05
Trip13 Trip13^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.57×10^-05
Prkab1 Prkab1^{tm1b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	CCP-IMG \| IMPC	1.64×10^-05
Paqr6 Paqr6^{tm1b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	BCM \| IMPC	1.74×10^-05
Tap1 Tap1^{tm2b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Echo \| HR	HMGU \| IMPC	1.78×10^-05
Bzw2 Bzw2^{tm1b(KOMP)Mbp}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	1.81×10^-05
Hunk Hunk^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	HMGU \| IMPC	1.90×10^-05
Gtpbp10 Gtpbp10^{tm1b(KOMP)Mbp}	HOM	Late adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	1.96×10^-05
Csmd3 Csmd3^em1(IMPC)Mbp	HOM	Late adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	1.97×10^-05
Cldn19 Cldn19^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.03×10^-05
Rnmt Rnmt^{tm1b(KOMP)Mbp}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.10×10^-05
Dnajc28 Dnajc28^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.11×10^-05
Mthfd2 Mthfd2^{tm1b(EUCOMM)Wtsi}	HET	Early adult	increased heart rate	Echo \| HR	BCM \| IMPC	2.23×10^-05
Klk8 Klk8^{em1(IMPC)Ccpcz}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	CCP-IMG \| IMPC	2.30×10^-05
Rnmt Rnmt^{tm1b(KOMP)Mbp}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.33×10^-05
Kctd11 Kctd11^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.65×10^-05
Ccdc30 Ccdc30^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.66×10^-05
Cgref1 Cgref1^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	2.72×10^-05
Asf1b Asf1b^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.78×10^-05
Sorbs2 Sorbs2^{tm1.1(KOMP)Mbp}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.84×10^-05
Trip13 Trip13^{tm1.1(KOMP)Vlcg}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	2.89×10^-05
Cnnm2 Cnnm2^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	3.02×10^-05
Asb1 Asb1^{em1(IMPC)Ccpcz}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	CCP-IMG \| IMPC	3.03×10^-05
Klk8 Klk8^{em1(IMPC)Ccpcz}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	CCP-IMG \| IMPC	3.05×10^-05
Dock11 Dock11^{tm2b(KOMP)Wtsi}	HEM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	3.05×10^-05
Nmral1 Nmral1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	3.22×10^-05
Kcnh3 Kcnh3^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	3.27×10^-05
Asb1 Asb1^{em1(IMPC)Ccpcz}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	CCP-IMG \| IMPC	3.31×10^-05
Dnase1l2 Dnase1l2^{tm1.1(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	HMGU \| IMPC	3.47×10^-05
Csmd3 Csmd3^em1(IMPC)Mbp	HOM	Late adult	increased heart rate	Electrocardiogram (ECG) \| HR	UC Davis \| IMPC	3.66×10^-05
Syce1 Syce1^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	3.71×10^-05
Psmc6 Psmc6^{tm1b(KOMP)Wtsi}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	3.86×10^-05
Spta1 Spta1^em1(IMPC)Bay	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	BCM \| IMPC	4.08×10^-05
Psmc6 Psmc6^{tm1b(KOMP)Wtsi}	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	4.10×10^-05
Kctd11 Kctd11^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	4.25×10^-05
Pcdh12 Pcdh12^em2(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	4.67×10^-05
Chtf18 Chtf18^{tm1b(KOMP)Wtsi}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.07×10^-05
Lrrc15 Lrrc15^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.18×10^-05
Acap1 Acap1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.30×10^-05
Fuca1 Fuca1^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.37×10^-05
Fgf9 Fgf9^{tm1b(KOMP)Wtsi}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.43×10^-05
Dnajc28 Dnajc28^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	5.57×10^-05
Cyp4f14 Cyp4f14^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	HMGU \| IMPC	5.69×10^-05
Wdr70 Wdr70^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.69×10^-05
Sycp3 Sycp3^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	5.88×10^-05
Wdr70 Wdr70^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	6.02×10^-05
Rnf10 Rnf10^{tm1b(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Echo \| HR	HMGU \| IMPC	6.17×10^-05
Rundc3a Rundc3a^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	BCM \| IMPC	6.18×10^-05
Spta1 Spta1^em1(IMPC)Bay	HET	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	BCM \| IMPC	6.21×10^-05
Asf1b Asf1b^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	6.44×10^-05
Chek2 Chek2^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	6.55×10^-05
Herpud2 Herpud2^{tm1.1(KOMP)Vlcg}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	UC Davis \| IMPC	6.73×10^-05
Cgref1 Cgref1^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	6.88×10^-05
Gk2 Gk2^em1(IMPC)J	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	7.09×10^-05
Fam124a Fam124a^{em1(IMPC)Ccpcz}	HOM	Early adult	increased heart rate	Echo \| HR	CCP-IMG \| IMPC	7.23×10^-05
Cyp4b1 Cyp4b1^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	HMGU \| IMPC	7.35×10^-05
Pitx3 Pitx3^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	7.82×10^-05
Espnl Espnl^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	8.17×10^-05
Cbx4 Cbx4^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	TCP \| IMPC	8.24×10^-05
Rec8 Rec8^{tm1b(KOMP)Wtsi}	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	8.43×10^-05
Rgs19 Rgs19^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	8.52×10^-05
Gk2 Gk2^em1(IMPC)J	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	8.69×10^-05
Dnase1l2 Dnase1l2^{tm1.1(KOMP)Wtsi}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	HMGU \| IMPC	8.69×10^-05
Bzw2 Bzw2^{tm1b(KOMP)Mbp}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	9.01×10^-05
Fmnl2 Fmnl2^em2(IMPC)Tcp	HOM	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	TCP \| IMPC	9.20×10^-05
Pax7 Pax7^{tm1.1(KOMP)Vlcg}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	JAX \| IMPC	9.46×10^-05
Fbxo38 Fbxo38^{em2(IMPC)Marc}	HOM	Early adult	increased heart rate	Echo \| HR	MARC \| IMPC	9.54×10^-05
Vsig4 Vsig4^{tm1b(EUCOMM)Hmgu}	HOM	Early adult	increased heart rate	Electrocardiogram (ECG) \| HR	JAX \| IMPC	9.67×10^-05
Ddx39a Ddx39a^{tm1b(KOMP)Wtsi}	HET	Early adult	shortened RR interval	Electrocardiogram (ECG) \| RR	BCM \| IMPC	9.82×10^-05

Download data as: TSV XLS

The way we measure

Procedure
Electrocardiogram (ECG)
Echo
Non-Invasive blood pressure

Phenotype associations stats

1.82% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart rate (90/4951)

0.84% females (41/4869) 0.55% males (26/4695)

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Phenotype: increased heart rate

IMPC Gene variants with increased heart rate

The way we measure

Phenotype associations stats

The IMPC Newsletter

Access Data Release 13.0 Data