Genes Phenotypes

Phenotype: increased heart rate

Definition
greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute
Synonyms
tachycardia
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased heart rate

Total number of significant genotype-phenotype associations: 76

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Gnb2
Gnb2em1(IMPC)J 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 3.75×10-09
Rrad
Rradtm1.1(KOMP)Vlcg 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 9.68×10-09
Klhl29
Klhl29tm1b(EUCOMM)Hmgu 		HOM postnatal increased heart rate Echo | HR ICS | IMPC 1.51×10-08
Rrad
Rradtm1.1(KOMP)Vlcg 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.66×10-08
Gnb2
Gnb2em1(IMPC)J 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.72×10-08
Fam161a
Fam161atm1b(KOMP)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.86×10-08
Adprm
Adprmtm1b(EUCOMM)Hmgu 		HOM postnatal increased heart rate Echo | HR HMGU | IMPC 1.52×10-07
Snai3
Snai3tm2b(EUCOMM)Hmgu 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 1.68×10-07
Fam161a
Fam161atm1b(KOMP)Wtsi 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.88×10-07
Tmprss11b
Tmprss11btm1b(KOMP)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 3.72×10-07
Snai3
Snai3tm2b(EUCOMM)Hmgu 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR BCM | IMPC 7.26×10-07
Fsd2
Fsd2em1(IMPC)Mbp 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 7.65×10-07
Mbd5
Mbd5tm1b(EUCOMM)Wtsi 		HET postnatal shortened RR interval Electrocardiogram (ECG) | RR ICS | IMPC 9.48×10-07
Tmprss11b
Tmprss11btm1b(KOMP)Wtsi 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR BCM | IMPC 1.80×10-06
Hunk
Hunktm1b(EUCOMM)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 3.40×10-06
Far2
Far2tm2b(KOMP)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.42×10-06
Fsd2
Fsd2em1(IMPC)Mbp 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 4.61×10-06
Hunk
Hunktm1b(EUCOMM)Wtsi 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR HMGU | IMPC 6.84×10-06
Leprotl1
Leprotl1tm1b(EUCOMM)Hmgu 		HOM postnatal increased heart rate Echo | HR MRC Harwell | IMPC 9.73×10-06
Zfp395
Zfp395tm1b(EUCOMM)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 1.23×10-05
Il18r1
Il18r1em1(IMPC)Mbp 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 1.30×10-05
Far2
Far2tm2b(KOMP)Wtsi 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 1.39×10-05
Bzw2
Bzw2tm1b(KOMP)Mbp 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.49×10-05
Trip13
Trip13tm1.1(KOMP)Vlcg 		HET postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.83×10-05
Phf19
Phf19tm1.1(KOMP)Vlcg 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.33×10-05
Sun1
Sun1tm1b(EUCOMM)Wtsi 		HOM postnatal increased heart rate Echo | HR ICS | IMPC 3.09×10-05
Lin28b
Lin28btm1b(EUCOMM)Hmgu 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.31×10-05
Sorbs2
Sorbs2tm1.1(KOMP)Mbp 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 3.42×10-05
Trim30b
Trim30btm1b(KOMP)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR BCM | IMPC 3.43×10-05
Hspb1
Hspb1tm1.1(KOMP)Vlcg 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.55×10-05
Rec8
Rec8tm1b(KOMP)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.77×10-05
Il2ra
Il2ratm1b(EUCOMM)Wtsi 		HOM postnatal increased heart rate Echo | HR ICS | IMPC 4.16×10-05
H1fx
H1fxtm1.1(KOMP)Vlcg 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.46×10-05
Ap3s1
Ap3s1tm1b(EUCOMM)Hmgu 		HOM postnatal increased heart rate Echo | HR HMGU | IMPC 4.50×10-05
Phf19
Phf19tm1.1(KOMP)Vlcg 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR UC Davis | IMPC 5.03×10-05
C9
C9tm1.1(KOMP)Vlcg 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.12×10-05
Pitx3
Pitx3tm1.1(KOMP)Vlcg 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 5.14×10-05
Prkab1
Prkab1tm1b(KOMP)Wtsi 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.71×10-05
Dock11
Dock11tm2b(KOMP)Wtsi 		HEM postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 5.82×10-05
Trip13
Trip13tm1.1(KOMP)Vlcg 		HET postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 6.17×10-05
Vsig8
Vsig8tm1.1(KOMP)Mbp 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 6.71×10-05
Arr3
Arr3em1(IMPC)J 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR JAX | IMPC 7.54×10-05
Pja2
Pja2tm1b(EUCOMM)Wtsi 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR BCM | IMPC 7.81×10-05
Nkg7
Nkg7tm1.1(KOMP)Vlcg 		HOM postnatal shortened RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 7.99×10-05
Trim30b
Trim30btm1b(KOMP)Wtsi 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR BCM | IMPC 9.06×10-05
Hspb1
Hspb1tm1.1(KOMP)Vlcg 		HOM postnatal increased heart rate Electrocardiogram (ECG) | HR JAX | IMPC 9.51×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo
Electrocardiogram (ECG)
Non-Invasive blood pressure

 Phenotype associations stats

0.87% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart rate (34/3922)

0.72% females (28/3898) 0.78% males (29/3716)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter