Gene: Plk1

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Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Plk1tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
decreased mean corpuscular hemoglobin concentration Plk1tm1b(EUCOMM)Hmgu HET Early adult 4.76×10-05
decreased monocyte cell number Plk1tm1b(EUCOMM)Hmgu HET Early adult 6.83×10-05
embryonic lethality prior to tooth bud stage Plk1tm1b(EUCOMM)Hmgu HOM   E12.5 0.00
embryonic lethality prior to organogenesis Plk1tm1b(EUCOMM)Hmgu HOM   E9.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64) N/A
5  (6/505) N/A
2  (1/73) N/A
5  (1/505) N/A
5  (1/506) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/59) N/A
5  (1/505) N/A
5  (5/505) N/A
5  (1/505) N/A
5  (6/505) N/A
5  (1/505) N/A
5  (1/503) N/A
5  (1/503) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/75) N/A
5  (1/503) N/A
2  (1/75) N/A
5  (1/505) N/A
2  (1/72) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/59) N/A
2  (1/59) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
21 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Ophthalmoscopy
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Histopathology
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Plk1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Plk1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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