Genes Phenotypes

Gene: Plk1

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Name
polo like kinase 1
MGI ID
MGI:97621
Synonyms
Plk STPK13
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (223) All data table (659)
Expression & images (29) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Plk1tm1b(EUCOMM)Hmgu HOM E9.5 0.00
preweaning lethality, complete penetrance Plk1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Plk1tm1b(EUCOMM)Hmgu HOM E12.5 0.00

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 5  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 5  (1/504) N/A
Embryo 5  (1/505) N/A
Eye 5  (1/504) N/A
Foot 5  (1/504) N/A
Forebrain 5  (1/504) N/A
Forelimb 5  (1/504) N/A
Gut 2  (1/56) N/A
Hand 5  (1/503) N/A
Head 5  (5/504) N/A
Heart 5  (1/504) N/A
Hindbrain 5  (6/504) N/A
Hindlimb 5  (1/503) N/A
Liver 5  (1/504) N/A
Lung 5  (1/500) N/A
Mandibular process 5  (1/504) N/A
Maxillary process 5  (1/504) N/A
Midbrain 5  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 5  (1/504) N/A
Skeleton 2  (1/70) N/A
Skin 5  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 5  (1/504) N/A
Tail somite 5  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
21 Images
Eye Morphology: Images Ophthalmoscopy
6 Images
Gross Pathology and Tissue Collection
8 Images
Histopathology
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Plk1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Plk1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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