Npr3 | natriuretic peptide receptor 3
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland
15 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
increased circulating phosphate level | 1 supporting dataset | Npr3tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.73x10-7 | ||
small testis | 1 supporting dataset | Npr3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
abnormal testis morphology | 1 supporting dataset | Npr3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
cecum | heterozygote | Section images | 50% (1/2) | 7.75% (22/284) |
cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Npr3.
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Npr3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Npr3tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Npr3tm199046(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |