Krt1 | keratin 1
Physiological systems
22 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Respiratory system Hematopoietic system Behavior/neurological Cardiovascular system
13 No significant impact
2 Not tested
Data collections
Gene metrics:20Significant phenotypes
14Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal heart morphology | 2 supporting datasets | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
increased effector memory CD8-positive, alpha-beta T cell number | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | 3.37x10-8 | ||
abnormal thymus morphology | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
small epididymis | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
decreased grip strength | 4 supporting datasets | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | 9x10-10 | ||
abnormal epididymis morphology | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
enlarged thymus | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
abnormal seminal vesicle morphology | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
small testis | 1 supporting dataset | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
enlarged heart | 2 supporting datasets | Krt1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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External links
No external links available for Krt1.
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Krt1em1(IMPC)Ccpcz | Exon Deletion | | mouse |
Krt1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
Krt1tm96263(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |