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Gene: Hoxd10 MGI:96202

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
homeobox D10
Synonyms:
Hox-5.3,  Hox-4.5

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxd10 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Hoxd10 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Vertical Talus, Congenital
Calcaneovalgus deformity, Rocker bottom foot, Equinus calcaneus, Arthritis OMIM:192950

The table below shows human diseases predicted to be associated to Hoxd10 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Posterior Fusion Of Lumbosacral Vertebrae-Blepharoptosis Syndrome
Abnormal form of the vertebral bodies, Joint stiffness, Posterior fusion of lumbosacral vertebrae... ORPHA:2064
Multiple Synostoses Syndrome 2
Carpal synostosis, Humeroradial synostosis, Talipes equinovarus, Finger symphalangism, Brachydact... OMIM:610017
Microcephaly With Cervical Spine Fusion Anomalies
Vertebral fusion, Spinal instability OMIM:251250
Spondyloepiphyseal Dysplasia Tarda, Kohn Type
Platyspondyly, Abnormal vertebral morphology, Abnormal ilium morphology, Abnormality of the ankle... ORPHA:163665
Pseudoachondroplasia
Delayed epiphyseal ossification, Hypoplasia of the odontoid process, Genu valgum, Wind-swept defo... ORPHA:750
Brachydactyly, Type B1
Joint contracture of the hand, Broad thumb, Hypoplastic sacrum, Delayed cranial suture closure, A... OMIM:113000
Vertebral Fusion, Posterior Lumbosacral, With Blepharoptosis
Posterior fusion of lumbosacral vertebrae OMIM:192800
Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1B
Talipes equinovarus, Short neck, Absent phalangeal crease, Fused thoracic vertebrae, Antecubital ... OMIM:618469
Metaphyseal Chondrodysplasia, Schmid Type
Abnormal vertebral morphology, Radial metaphyseal irregularity, Genu varum, Irregular vertebral e... ORPHA:174
Ring Chromosome 21 Syndrome
Small hand, Clinodactyly, Thoracic hemivertebrae, Azoospermia, Amenorrhea, Gait disturbance, Fuse... ORPHA:1445
Spondylocostal Dysostosis 1, Autosomal Recessive
Block vertebrae, Abnormal odontoid process morphology, Vertebral segmentation defect, Kyphoscolio... OMIM:277300
X-Linked Skeletal Dysplasia-Intellectual Disability Syndrome
Thoracic hemivertebrae, Brachydactyly, Abnormal sacrum morphology, Scoliosis, Short middle phalan... ORPHA:1436
Otopalatodigital Syndrome Type 1
Short distal phalanx of finger, Limitation of joint mobility, Synostosis of carpal bones, Elbow d... ORPHA:90650
Progressive Pseudorheumatoid Arthropathy Of Childhood
Abnormal ilium morphology, Joint contracture of the hand, Limitation of joint mobility, Genu valg... ORPHA:1159
Intellectual Disability-Facial Dysmorphism-Hand Anomalies Syndrome
Short distal phalanx of finger, Short distal phalanx of the thumb, Short 3rd metacarpal, Short to... ORPHA:370010
Isolated Klippel-Feil Syndrome
Abnormality of the vertebral column, Abnormal shoulder morphology, Abnormal cranial nerve morphol... ORPHA:2345
Chromosome 8Q22.1 Duplication Syndrome
Genu recurvatum, Short stepped shuffling gait, Broad thumb, Limitation of joint mobility, Interph... OMIM:151200
Multiple Epiphyseal Dysplasia Type 5
Difficulty walking, Premature osteoarthritis, Limited hip movement, Genu valgum, Intervertebral d... ORPHA:93311
Vertebral, Cardiac, Renal, And Limb Defects Syndrome 3
Vertebral segmentation defect, Talipes equinovarus, Short long bone, Vertebral fusion, Sacral dimple OMIM:618845
Spondylometaphyseal Dysplasia, 'Corner Fracture' Type
Abnormal vertebral morphology, Limitation of joint mobility, Clinodactyly, Hypoplastic iliac wing... ORPHA:93315
Keratoconus Posticus Circumscriptus
Limited elbow extension and supination, Short neck, Brachydactyly, Clinodactyly of the 5th finger... OMIM:244600
Acropectorovertebral Dysplasia
Abnormal vertebral morphology, Toe syndactyly, Synostosis of carpal bones, Spina bifida occulta a... OMIM:102510
Klippel-Feil Syndrome 3, Autosomal Dominant
Cervical C5/C6 vertebrae fusion, Cervical C3/C4 vertebral fusion, Thoracic scoliosis OMIM:613702
Fibular Aplasia Or Hypoplasia, Femoral Bowing And Poly-, Syn-, And Oligodactyly
Aplasia/Hypoplasia of fingers, Toe syndactyly, Radial bowing, Finger syndactyly, Clinodactyly, Hy... OMIM:228930
Muscular Dystrophy-Dystroglycanopathy (Congenital With Or Without Impaired Intellectual Development), Type B, 5
Tip-toe gait, Elbow contracture, Difficulty walking, Hyperlordosis, Achilles tendon contracture, ... OMIM:606612
Diaphanospondylodysostosis
Absent or minimally ossified vertebral bodies, Short neck, Narrow pelvis bone, Abnormal vertebral... ORPHA:66637
Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C, 5
Tip-toe gait, Difficulty walking, Hyperlordosis, Achilles tendon contracture, Vertebral fusion, S... OMIM:607155
Christian Syndrome
Thoracic hemivertebrae, Prominent metopic ridge, Scoliosis, Short middle phalanx of finger, Fused... OMIM:309620
Spondylocostal Dysostosis 5
Butterfly vertebrae, Low back pain, Short neck, Hemivertebrae, Vertebral fusion, Scoliosis OMIM:122600
Léri-Weill Dyschondrosteosis
Elbow dislocation, Radial bowing, Short tibia, Abnormal tibia morphology, Genu valgum, Patellar a... ORPHA:240
Developmental And Speech Delay Due To Sox5 Deficiency
Optic atrophy, Lumbar hyperlordosis, Butterfly vertebrae, 2-3 toe syndactyly, Vertebral fusion, T... ORPHA:313892
Spondyloepimetaphyseal Dysplasia, Missouri Type
Pear-shaped vertebrae, Platyspondyly, Rhizomelia, Metaphyseal cupping, Radial bowing, Delayed ske... OMIM:602111
Kniest Dysplasia
Delayed epiphyseal ossification, Enlarged metaphyses, Hypoplasia of the odontoid process, Abnorma... ORPHA:485
Spondylometaphyseal Dysplasia, Kozlowski Type
Delayed epiphyseal ossification, Abnormal ilium morphology, Hypoplasia of the odontoid process, R... ORPHA:93314
Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1A
Popliteal pterygium, Arthrogryposis multiplex congenita, Cervical spinal canal stenosis, Carpal s... OMIM:178110
Tibial Aplasia-Ectrodactyly Syndrome
Aplasia/Hypoplasia of the tibia, Popliteal pterygium, Limitation of joint mobility, Finger syndac... ORPHA:3329
Postaxial Polydactyly-Dental And Vertebral Anomalies Syndrome
Abnormal form of the vertebral bodies, Elbow dislocation, Clinodactyly of the 5th finger, Postaxi... ORPHA:2916
Wildervanck Syndrome
Pseudopapilledema, Fused cervical vertebrae OMIM:314600
Fibrodysplasia Ossificans Progressiva
Broad femoral neck, Short 1st metacarpal, Small cervical vertebral bodies, Ectopic ossification i... OMIM:135100
Cardioneuromyopathy With Hyaline Masses And Nemaline Rods
Fusion of midcervical facet joints, Widening of cervical spinal canal, Cervical vertebral bodies ... OMIM:606842
Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension
Sandal gap, Patellar hypoplasia, Hypoplasia of the lesser trochanter, Patellar aplasia, Talocalca... OMIM:147891
Multiple Pterygium Syndrome, Lethal Type
Joint dislocation, Short finger, Akinesia, Increased susceptibility to fractures, Multiple pteryg... OMIM:253290
Verheij Syndrome
Short 5th finger, Clinodactyly, Joint hypermobility, Short neck, Hemivertebrae, Vertebral fusion,... OMIM:615583
Familial Congenital Mirror Movements
Hypogonadotropic hypogonadism, Fused cervical vertebrae ORPHA:238722
Kbg Syndrome
Delayed skeletal maturation, Persistent open anterior fontanelle, Finger clinodactyly, Short neck... ORPHA:2332
Tibial Hemimelia-Polysyndactyly-Triphalangeal Thumb Syndrome
Aplasia/Hypoplasia of the tibia, Synostosis of carpal bones, Patellar aplasia, Aplasia/Hypoplasia... ORPHA:988
Thrombocytopenia-Absent Radius Syndrome
Broad thumb, Finger syndactyly, Tibial torsion, Absent radius, Fibular aplasia, Aplasia/hypoplasi... ORPHA:3320
Klippel-Feil Syndrome 2, Autosomal Recessive
Cervical C2/C3 vertebral fusion, Short neck, Scoliosis, Fused cervical vertebrae OMIM:214300
Spondylocarpotarsal Synostosis Syndrome
Epiphyseal dysplasia, Hypoplasia of the odontoid process, Carpal synostosis, C2-C3 subluxation, T... OMIM:272460
Multiple Pterygium Syndrome, X-Linked
Joint dislocation, Short finger, Increased susceptibility to fractures, Multiple pterygia, Abnorm... OMIM:312150
Aarskog-Scott Syndrome
Genu recurvatum, Small hand, Finger syndactyly, Camptodactyly of finger, Joint hypermobility, Abn... ORPHA:915
Nail-Patella Syndrome
Abnormal tibia morphology, Contracture of the distal interphalangeal joint of the fingers, Patell... ORPHA:2614
Wildervanck Syndrome
Short neck, Pseudopapilledema, Facial palsy, Fused cervical vertebrae ORPHA:3456
Sillence Syndrome
Abnormal vertebral morphology, Broad thumb, Intervertebral disk degeneration, Flat acetabular roo... ORPHA:3168
Laurin-Sandrow Syndrome
Patellar aplasia, Hand polydactyly, Triphalangeal thumb, Absent tibia, Absent radius, Fibular dup... OMIM:135750
Lamb-Shaffer Syndrome
Ataxia, Optic atrophy, Fused cervical vertebrae, Hip dysplasia, Scoliosis, Thoracic kyphosis ORPHA:530983
Stapes Ankylosis With Broad Thumbs And Toes
Short distal phalanx of finger, Toe syndactyly, Broad thumb, Broad hallux, Proximal/middle sympha... OMIM:184460
Spondyloepimetaphyseal Dysplasia, Shohat Type
Delayed epiphyseal ossification, Abnormal vertebral morphology, Premature osteoarthritis, Squared... ORPHA:93352
Klippel-Feil Syndrome 1, Autosomal Dominant
Cervical C2/C3 vertebral fusion, Short neck, Abnormal limb bone morphology, Scoliosis, Abnormal v... OMIM:118100
Spondylocostal Dysostosis 4, Autosomal Recessive
Block vertebrae, Abnormal odontoid process morphology, Vertebral segmentation defect, Spina bifid... OMIM:613686
Atelosteogenesis, Type I
Elbow dislocation, Radial bowing, Fibular aplasia, Talipes equinovarus, Short neck, Aplasia/Hypop... OMIM:108720
Frontometaphyseal Dysplasia 1
Broad phalanges of the hand, Partial fusion of carpals, Carpal synostosis, Genu valgum, Limited e... OMIM:305620
Multiple Pterygium Syndrome, Escobar Variant
Intercrural pterygium, Dysplastic patella, Patellar aplasia, Arachnodactyly, Talipes equinovarus,... OMIM:265000
Larsen Syndrome
Hypoplastic cervical vertebrae, Elbow dislocation, Talipes equinovarus, Beaking of vertebral bodi... OMIM:150250
Acro-Renal-Ocular Syndrome
Toe syndactyly, Short distal phalanx of the thumb, Finger syndactyly, Optic disc coloboma, Aplasi... ORPHA:959
Ehlers-Danlos Syndrome, Classic-Like, 2
Osteopenia, Squared iliac bones, Knee dislocation, Generalized joint hypermobility, Cervical C2/C... OMIM:618000
Klippel-Feil Syndrome 4, Autosomal Recessive, With Nemaline Myopathy And Facial Dysmorphism
Acetabular dysplasia, Cervical C2/C3 vertebral fusion, Short neck, Thoracolumbar scoliosis, Flexi... OMIM:616549
Microcephaly, Short Stature, And Limb Abnormalities
Delayed skeletal maturation, Patellar hypoplasia, Patellar aplasia, Radioulnar synostosis, Brachy... OMIM:617604
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Abnormal hip bone morphology, Short neck, Hyperlordosis, Kyphosis, Fused cervical vertebrae ORPHA:2522
Split-Hand/Foot Malformation With Long Bone Deficiency 1
Patellar aplasia, Short hallux, Absent tibia, Split hand, Aplasia/Hypoplasia of the ulna, Aplasia... OMIM:119100
Arnold-Chiari Malformation Type I
Progressive cerebellar ataxia, Cranial nerve compression, Stiff neck, Abnormality of the vestibul... ORPHA:268882
Caudal Regression Syndrome
Abnormal pelvic girdle bone morphology, Aplasia/Hypoplasia of the sacrum, Joint stiffness, Hypopl... ORPHA:3027
Alkaptonuria
Limited hip movement, Intervertebral disk degeneration, Arthropathy, Low back pain, Limited shoul... OMIM:203500
Robinow Syndrome, Autosomal Recessive 1
Bifid distal phalanx of toe, Small hand, Broad thumb, Clinodactyly, Radial bowing, Delayed crania... OMIM:268310
Mayer-Rokitansky-Küster-Hauser Syndrome
Abnormal form of the vertebral bodies, Endometriosis, Vertebral segmentation defect, Dyspareunia,... ORPHA:3109
Frontometaphyseal Dysplasia
Joint contracture of the hand, Short distal phalanx of the thumb, Broad thumb, Limited elbow move... ORPHA:1826
Otopalatodigital Syndrome Type 2
Synostosis of carpal bones, Elbow dislocation, Short thumb, Camptodactyly of finger, Carpal synos... ORPHA:90652
Sifrim-Hitz-Weiss Syndrome
Gait imbalance, Short clavicles, Wormian bones, Hypogonadotropic hypogonadism, Tapered finger, Fl... OMIM:617159
Patella Aplasia-Hypoplasia
Patellar aplasia, Patellar hypoplasia OMIM:168860
Koolen-De Vries Syndrome
Hip dislocation, Vertebral segmentation defect, Joint hypermobility, Arachnodactyly, Vertebral fu... ORPHA:96169
Mosaic Trisomy 20
Clinodactyly, Spinal canal stenosis, Vertebral segmentation defect, Down-sloping shoulders, Limit... ORPHA:1724
Gorlin Syndrome
Abnormal vertebral morphology, Vertebral wedging, Arachnodactyly, Hypogonadotropic hypogonadism, ... ORPHA:377
Duane-Radial Ray Syndrome
Radial deviation of the hand, Absent thumb, Short thumb, Sandal gap, Preaxial polydactyly, Absent... OMIM:607323
Kbg Syndrome
Radial deviation of finger, Delayed skeletal maturation, Ulnar deviation of the 2nd finger, Clino... OMIM:148050
Koolen-De Vries Syndrome
Slender finger, Kyphosis, Prominent fingertip pads, Spondylolisthesis, Joint hypermobility, Hip d... OMIM:610443
Intellectual Developmental Disorder With Dysmorphic Facies And Ptosis
Cervical C2/C3 vertebral fusion, Talipes equinovarus, Camptodactyly, Joint hypermobility OMIM:617333
Fryns-Smeets-Thiry Syndrome
Patellar aplasia, Joint hypermobility, Arachnodactyly, Scoliosis, Hip dislocation ORPHA:2058
Lateral Meningocele Syndrome
Sclerosis of skull base, Biconcave vertebral bodies, Joint hypermobility, Wormian bones, Short ne... OMIM:130720
Craniofacial Dysmorphism, Skeletal Anomalies, And Impaired Intellectual Development Syndrome 1
Overlapping toe, Joint hypermobility, Talipes equinovarus, Short neck, Beaking of vertebral bodie... OMIM:213980
Basal Cell Nevus Syndrome 1
Short distal phalanx of the thumb, Vertebral wedging, Kyphoscoliosis, Polydactyly, Short 4th meta... OMIM:109400
Nail-Patella Syndrome
Elongated radius, Patellar hypoplasia, Hypoplastic radial head, Lumbar hyperlordosis, Limited elb... OMIM:161200
Myhre Syndrome
Platyspondyly, Cone-shaped epiphysis, Limitation of joint mobility, Clinodactyly, Short toe, Shor... OMIM:139210
Thrombocytopenia-Absent Radius Syndrome
Short forearm, Broad thumb, Finger syndactyly, Carpal synostosis, Fibular aplasia, Patellar aplas... OMIM:274000
Fanconi Anemia, Complementation Group I
Absent thumb, Short 1st metacarpal, Short thumb, Short neck, Fused cervical vertebrae, Hypoplasia... OMIM:609053
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Block vertebrae, Supernumerary vertebrae, Short neck, Hemivertebrae, Vertebral fusion, Scoliosis OMIM:271520
Intellectual Disability-Cardiac Anomalies-Short Stature-Joint Laxity Syndrome
Broad thumb, Thoracic hemivertebrae, Overlapping toe, Abnormal optic disc morphology, Short neck,... ORPHA:508498
Meier-Gorlin Syndrome 1
Joint contracture of the hand, Small hand, Elbow dislocation, Cutaneous finger syndactyly, Genu v... OMIM:224690
Microphthalmia, Syndromic 3
Optic nerve aplasia, Butterfly vertebrae, Hypogonadotropic hypogonadism, Hemivertebrae, Vertebral... OMIM:206900
Faciodigitogenital Syndrome, Autosomal Recessive
Clinodactyly of the 5th finger, Down-sloping shoulders, Hyperextensible hand joints, Metatarsus a... OMIM:227330
Roberts Syndrome
Synostosis of carpal bones, Finger syndactyly, Sandal gap, Radial deviation of finger, Proximal p... ORPHA:3103
Shashi-Pena Syndrome
Cervical C2/C3 vertebral fusion, Short metacarpal, Accelerated skeletal maturation, Osteoporosis,... OMIM:617190
Apert Syndrome
Lambdoidal craniosynostosis, Coronal craniosynostosis, Delayed epiphyseal ossification, Broad thu... OMIM:101200
Duane Retraction Syndrome
Abnormal form of the vertebral bodies, Preaxial hand polydactyly, Talipes equinovarus, Short neck... ORPHA:233
Mosaic Trisomy 8
Limitation of joint mobility, Arthrogryposis multiplex congenita, Camptodactyly of finger, Patell... ORPHA:96061
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Osteopenia, Osteomyelitis, Joint swelling, Osteolysis, Fused cervical vertebrae OMIM:612852
Meier-Gorlin Syndrome 5
Clinodactyly, Elbow dislocation, Delayed skeletal maturation, Slender long bone, Hypoplasia of th... OMIM:613805
Apert Syndrome
Optic atrophy, Toe syndactyly, Broad thumb, Finger syndactyly, Micromelia, Cervical C5/C6 vertebr... ORPHA:87
Simpson-Golabi-Behmel Syndrome
Congenital hip dislocation, Toe syndactyly, Broad thumb, Finger syndactyly, Short toe, Camptodact... ORPHA:373
9Q33.3Q34.11 Microdeletion Syndrome
Bilateral coxa valga, Patellar hypoplasia, Inability to walk, Patellar aplasia, Talipes equinovar... ORPHA:495818
Intellectual Developmental Disorder, Autosomal Dominant 52
Cervical C2/C3 vertebral fusion, Lumbar hyperlordosis, Lumbar scoliosis OMIM:617796
Genitopatellar Syndrome
Hypoplastic ilia, Patellar aplasia, Knee flexion contracture, Hip contracture, Radioulnar synosto... ORPHA:85201
Aicardi Syndrome
Optic atrophy, Block vertebrae, Small hand, Optic disc coloboma, Butterfly vertebrae, Hip dysplas... ORPHA:50
Frontometaphyseal Dysplasia 2
Congenital hip dislocation, Broad thumb, Finger clinodactyly, Elbow contracture, Flared metaphysi... OMIM:617137
Vertebral, Cardiac, Tracheoesophageal, Renal, And Limb Defects
Spina bifida occulta, Butterfly vertebrae, Fused cervical vertebrae OMIM:619227
Wolf-Hirschhorn Syndrome
Hip dislocation, Pseudoepiphyses of the metacarpals, Abnormal form of the vertebral bodies, Delay... OMIM:194190
Holt-Oram Syndrome
Hypoplastic scapulae, Short forearm, Elbow dislocation, Radial bowing, Ulnar deviation of thumb, ... OMIM:142900
Aicardi Syndrome
Optic atrophy, Block vertebrae, Optic disc coloboma, Butterfly vertebrae, Hemivertebrae, Scoliosi... OMIM:304050
Meier-Gorlin Syndrome 4
Genu recurvatum, Slender long bone, Patellar aplasia, Delayed skeletal maturation OMIM:613804
Robinow Syndrome
Short distal phalanx of finger, Kyphoscoliosis, Bifid distal phalanx of the thumb, Brachydactyly,... ORPHA:97360
Rothmund-Thomson Syndrome Type 2
Osteopenia, Joint dislocation, Patellar hypoplasia, Delayed skeletal maturation, Pathologic fract... ORPHA:221016
Baller-Gerold Syndrome
Lambdoidal craniosynostosis, Abnormal vertebral morphology, Carpal synostosis, Patellar aplasia, ... OMIM:218600
Meier-Gorlin Syndrome 2
Tracheomalacia, Delayed skeletal maturation, Slender long bone, Patellar aplasia, Joint hypermobi... OMIM:613800
Rothmund-Thomson Syndrome Type 1
Osteopenia, Patellar hypoplasia, Delayed skeletal maturation, Hypogonadism, Metaphyseal sclerosis... ORPHA:221008
Penoscrotal Transposition
Clinodactyly of the 5th finger, Patellar aplasia ORPHA:2842
Chromosome 16P13.3 Duplication Syndrome
Short toe, Short thumb, Sandal gap, Cervical C5/C6 vertebrae fusion, Proximal placement of hallux... OMIM:613458
Chops Syndrome
Cervical C2/C3 vertebral fusion, Optic atrophy, Brachydactyly, Tracheomalacia OMIM:616368
Thakker-Donnai Syndrome
Cervical C2/C3 vertebral fusion, Short neck, Hemivertebrae ORPHA:1780
Cardiospondylocarpofacial Syndrome
Cone-shaped epiphysis, Delayed skeletal maturation, Fusion of middle ear ossicles, Carpal synosto... OMIM:157800
Meier-Gorlin Syndrome 3
Tracheomalacia, Patellar hypoplasia, Delayed skeletal maturation, Slender long bone, Patellar apl... OMIM:613803
Recombinant 8 Syndrome
Clinodactyly of the 5th finger, Scoliosis, Patellar aplasia, Camptodactyly of finger ORPHA:96167
Ear-Patella-Short Stature Syndrome
Aplastic clavicle, Abnormal epiphysis morphology, Elbow dislocation, Delayed skeletal maturation,... ORPHA:2554
Heterotaxy, Visceral, 1, X-Linked
Congenital hip dislocation, Block vertebrae, Absence of the sacrum, Short long bone, Bilateral ta... OMIM:306955
Cognitive Impairment-Coarse Facies-Heart Defects-Obesity-Pulmonary Involvement-Short Stature-Skeletal Dysplasia Syndrome
Abnormal vertebral morphology, Small hand, Tracheomalacia, Hypoplasia of proximal radius, Fibular... ORPHA:444077
Meier-Gorlin Syndrome 6
Sandal gap, Delayed skeletal maturation, Patellar aplasia, Hip dysplasia, Tracheobronchomalacia, ... OMIM:616835
Agammaglobulinemia-Microcephaly-Craniosynostosis-Severe Dermatitis Syndrome
Coronal craniosynostosis, Overlapping toe, Contracture of the distal interphalangeal joint of the... ORPHA:83617
Genitopatellar Syndrome
Congenital hip dislocation, Inferior pubic ramus hypoplasia, Patellar aplasia, Knee flexion contr... OMIM:606170
Osteogenesis Imperfecta
Cervical kyphosis, Abnormal form of the vertebral bodies, Enlarged vertebral pedicles, Biconcave ... ORPHA:666
Elsahy-Waters Syndrome
Shortening of all phalanges of fingers, Cutaneous finger syndactyly, Cervical C2/C3 vertebral fus... OMIM:211380
Generalized Arterial Calcification Of Infancy
Osteomalacia, Abnormal hip joint morphology, Hypophosphatemic rickets, Abnormal calcification of ... ORPHA:51608
Craniofacial Microsomia 1
Block vertebrae, Genu valgum, Partial duplication of thumb phalanx, Hemivertebrae, Scoliosis, Ver... OMIM:164210
Vertical Talus, Congenital
Calcaneovalgus deformity, Rocker bottom foot, Equinus calcaneus, Arthritis OMIM:192950

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxd10

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxd10.

No publications found that use IMPC mice or data for Hoxd10.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hoxd10tm413647(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Hoxd10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

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