Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

homeobox D10
Hox-5.3,  Hox-4.5

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Not Significant
Not tested


The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxd10 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Hoxd10 by orthology or direct annotation.

Disease Similarity of
Matching phenotypes Source
Vertical Talus, Congenital
Rocker bottom foot, Arthritis, Equinus calcaneus, Calcaneovalgus deformity OMIM:192950

The table below shows human diseases predicted to be associated to Hoxd10 by phenotypic similarity.

Disease Similarity of
Matching phenotypes Source
Posterior Fusion Of Lumbosacral Vertebrae-Blepharoptosis Syndrome
Sacral dimple, Posterior fusion of lumbosacral vertebrae, Tarsal synostosis, Abnormal form of the... ORPHA:2064
Multiple Synostoses Syndrome 2
Finger symphalangism, Tarsal synostosis, Talipes equinovarus, Proximal symphalangism, Humeroradia... OMIM:610017
Microcephaly With Cervical Spine Fusion Anomalies
Spinal instability, Vertebral fusion OMIM:251250
Spondyloepiphyseal Dysplasia Tarda, Kohn Type
Restricted large joint movement, Abnormal vertebral morphology, Abnormal ilium morphology, Bilate... ORPHA:163665
Abnormal form of the vertebral bodies, Short long bone, Increased laxity of ankles, Flat acetabul... ORPHA:750
Brachydactyly, Type B1
Joint contracture of the hand, Hypoplastic sacrum, Aplasia/Hypoplasia of the distal phalanges of ... OMIM:113000
Vertebral Fusion, Posterior Lumbosacral, With Blepharoptosis
Posterior fusion of lumbosacral vertebrae OMIM:192800
Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1B
Tarsal synostosis, Fused cervical vertebrae, Scoliosis, Absent phalangeal crease, Antecubital pte... OMIM:618469
Metaphyseal Chondrodysplasia, Schmid Type
Short tubular bones of the hand, Distal femoral metaphyseal irregularity, Femoral bowing, Short l... ORPHA:174
Ring Chromosome 21 Syndrome
Azoospermia, Scoliosis, Infertility, Gait disturbance, Thoracic hemivertebrae, Syndactyly, Fused ... ORPHA:1445
Spondylocostal Dysostosis 1, Autosomal Recessive
Kyphoscoliosis, Abnormal odontoid process morphology, Hemivertebrae, Vertebral segmentation defec... OMIM:277300
X-Linked Skeletal Dysplasia-Intellectual Disability Syndrome
Fused cervical vertebrae, Scoliosis, Short middle phalanx of finger, Thoracic hemivertebrae, Brac... ORPHA:1436
Otopalatodigital Syndrome Type 1
Proximal placement of thumb, Sandal gap, Abnormal metacarpal morphology, Increased bone mineral d... ORPHA:90650
Progressive Pseudorheumatoid Arthropathy Of Childhood
Wrist swelling, Hyperlordosis, Generalized osteoporosis, Broad femoral neck, Abnormality of hand ... ORPHA:1159
Intellectual Disability-Facial Dysmorphism-Hand Anomalies Syndrome
Difficulty walking, Cervical C2/C3 vertebral fusion, Osseous finger syndactyly, 3-4 finger cutane... ORPHA:370010
Isolated Klippel-Feil Syndrome
Abnormal shoulder morphology, Cervical C2/C3 vertebral fusion, Abnormality of the vertebral colum... ORPHA:2345
Chromosome 8Q22.1 Duplication Syndrome
Cubitus valgus, Cervical C2/C3 vertebral fusion, Short metatarsal, Genu recurvatum, Limitation of... OMIM:151200
Multiple Epiphyseal Dysplasia Type 5
Joint stiffness, Genu varum, Difficulty walking, Knee pain, Back pain, Hip dysplasia, Limited hip... ORPHA:93311
Vertebral, Cardiac, Renal, And Limb Defects Syndrome 3
Sacral dimple, Short long bone, Vertebral segmentation defect, Talipes equinovarus, Vertebral fusion OMIM:618845
Spondylometaphyseal Dysplasia, 'Corner Fracture' Type
Abnormal bone ossification, Reduced bone mineral density, Biconvex vertebral bodies, Hypoplastic ... ORPHA:93315
Keratoconus Posticus Circumscriptus
Clinodactyly of the 5th finger, Limited elbow extension and supination, Brachydactyly, Short neck... OMIM:244600
Acropectorovertebral Dysplasia
Abnormal vertebral morphology, Spina bifida occulta at L5, Finger syndactyly, Synostosis of carpa... OMIM:102510
Klippel-Feil Syndrome 3, Autosomal Dominant
Thoracic scoliosis, Cervical C3/C4 vertebral fusion, Cervical C5/C6 vertebrae fusion OMIM:613702
Fibular Aplasia Or Hypoplasia, Femoral Bowing And Poly-, Syn-, And Oligodactyly
Aplasia/hypoplasia of the femur, Hypoplastic iliac wing, Femoral bowing, Hypoplastic pelvis, Apla... OMIM:228930
Muscular Dystrophy-Dystroglycanopathy (Congenital With Or Without Impaired Intellectual Development), Type B, 5
Tip-toe gait, Difficulty walking, Scoliosis, Hyperlordosis, Facial palsy, Kyphosis, Achilles tend... OMIM:606612
Narrow pelvis bone, Absent or minimally ossified vertebral bodies, Short neck, Abnormal vertebral... ORPHA:66637
Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C, 5
Tip-toe gait, Difficulty walking, Scoliosis, Hyperlordosis, Waddling gait, Kyphosis, Achilles ten... OMIM:607155
Mental Retardation, Skeletal Dysplasia, And Abducens Palsy
Fused cervical vertebrae, Scoliosis, Prominent metopic ridge, Short middle phalanx of finger, Tho... OMIM:309620
Spondylocostal Dysostosis 5
Butterfly vertebrae, Scoliosis, Hemivertebrae, Low back pain, Short neck, Vertebral fusion OMIM:122600
Léri-Weill Dyschondrosteosis
Abnormal femur morphology, Abnormal hip bone morphology, Tibial bowing, Joint stiffness, Mesomeli... ORPHA:240
Developmental And Speech Delay Due To Sox5 Deficiency
Optic atrophy, Butterfly vertebrae, Scoliosis, Thoracic kyphoscoliosis, 2-3 toe syndactyly, Lumba... ORPHA:313892
Spondyloepimetaphyseal Dysplasia, Missouri Type
Limited elbow extension, Rhizomelia, Small epiphyses, Ulnar bowing, Pear-shaped vertebrae, Irregu... OMIM:602111
Kniest Dysplasia
Enlarged metaphyses, Short long bone, Dumbbell-shaped long bone, Joint stiffness, Flexion contrac... ORPHA:485
Spondylometaphyseal Dysplasia, Kozlowski Type
Short tubular bones of the hand, Short greater sciatic notch, Flat acetabular roof, Kyphosis, Fla... ORPHA:93314
Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1A
Cervical spinal canal stenosis, Popliteal pterygium, Tarsal synostosis, Spondylolisthesis, Multip... OMIM:178110
Tibial Aplasia-Ectrodactyly Syndrome
Popliteal pterygium, Fibular hypoplasia, Abnormal fibula morphology, Abnormal femur morphology, F... ORPHA:3329
Postaxial Polydactyly-Dental And Vertebral Anomalies Syndrome
Clinodactyly of the 5th finger, Abnormal form of the vertebral bodies, Scoliosis, Hemivertebrae, ... ORPHA:2916
Wildervanck Syndrome
Fused cervical vertebrae, Pseudopapilledema OMIM:314600
Fibrodysplasia Ossificans Progressiva
Abnormality of the first metatarsal bone, Clinodactyly of the 5th finger, Short hallux, Ectopic o... OMIM:135100
Cardioneuromyopathy With Hyaline Masses And Nemaline Rods
Fusion of midcervical facet joints, Widening of cervical spinal canal, Cervical vertebral bodies ... OMIM:606842
Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension
Tarsal synostosis, Patellar hypoplasia, Sandal gap, Flat capital femoral epiphysis, Short femur, ... OMIM:147891
Multiple Pterygium Syndrome, Lethal Type
Short finger, Akinesia, Multiple pterygia, Joint dislocation, Abnormal cervical curvature, Verteb... OMIM:253290
Verheij Syndrome
Optic nerve hypoplasia, Scoliosis, Hemivertebrae, Short 5th finger, Joint hypermobility, Short ne... OMIM:615583
Familial Congenital Mirror Movements
Fused cervical vertebrae, Hypogonadotropic hypogonadism ORPHA:238722
Kbg Syndrome
Finger clinodactyly, Scoliosis, Thoracic kyphosis, Persistent open anterior fontanelle, Delayed s... ORPHA:2332
Tibial Hemimelia-Polysyndactyly-Triphalangeal Thumb Syndrome
Abnormal fibula morphology, Aplasia/Hypoplasia of the thumb, Synostosis of carpal bones, Aplasia/... ORPHA:988
Thrombocytopenia-Absent Radius Syndrome
Fibular aplasia, Fused cervical vertebrae, Clinodactyly of the 5th finger, Aplasia/Hypoplasia of ... ORPHA:3320
Klippel-Feil Syndrome 2, Autosomal Recessive
Short neck, Scoliosis, Fused cervical vertebrae, Cervical C2/C3 vertebral fusion OMIM:214300
Spondylocarpotarsal Synostosis Syndrome
Hyperlordosis, Short metacarpal, Delayed skeletal maturation, Tarsal synostosis, Bowed humerus, S... OMIM:272460
Aarskog-Scott Syndrome
Clinodactyly of the 5th finger, Genu recurvatum, Finger syndactyly, Short foot, Camptodactyly of ... ORPHA:915
Multiple Pterygium Syndrome, X-Linked
Short finger, Multiple pterygia, Joint dislocation, Abnormal cervical curvature, Vertebral fusion... OMIM:312150
Nail-Patella Syndrome
Reduced bone mineral density, Spondylolysis, Spondylolisthesis, Abnormal femur morphology, Disloc... ORPHA:2614
Wildervanck Syndrome
Facial palsy, Short neck, Fused cervical vertebrae, Pseudopapilledema ORPHA:3456
Sillence Syndrome
Flat acetabular roof, Large iliac wing, Broad metatarsal, Broad thumb, Abnormal morphology of the... ORPHA:3168
Laurin-Sandrow Syndrome
Triphalangeal thumb, Absent tibia, Fibular duplication, Hand polydactyly, Patellar aplasia, Synda... OMIM:135750
Lamb-Shaffer Syndrome
Optic atrophy, Fused cervical vertebrae, Scoliosis, Thoracic kyphosis, Ataxia, Hip dysplasia ORPHA:530983
Stapes Ankylosis With Broad Thumbs And Toes
Fused cervical vertebrae, Proximal/middle symphalangism of 5th finger, Broad thumb, Broad hallux,... OMIM:184460
Spondyloepimetaphyseal Dysplasia, Shohat Type
Generalized bone demineralization, Hyperlordosis, Short long bone, Metaphyseal irregularity, Abno... ORPHA:93352
Klippel-Feil Syndrome 1, Autosomal Dominant
Cervical C2/C3 vertebral fusion, Scoliosis, Short neck, Abnormal vertebral segmentation and fusio... OMIM:118100
Spondylocostal Dysostosis 4, Autosomal Recessive
Abnormal odontoid process morphology, Spina bifida occulta, Scoliosis, Hemivertebrae, Vertebral s... OMIM:613686
Frontometaphyseal Dysplasia 1
Limited elbow movement, Cervical C2/C3 vertebral fusion, Dislocated radial head, Wrist flexion co... OMIM:305620
Atelosteogenesis, Type I
Clubbing, Tibial bowing, Short metacarpal, Short humerus, Thoracic platyspondyly, Fibular aplasia... OMIM:108720
Multiple Pterygium Syndrome, Escobar Variant
Rocker bottom foot, Dislocated radial head, Kyphosis, Arachnodactyly, Syndactyly, Hip dislocation... OMIM:265000
Larsen Syndrome
Multiple carpal ossification centers, Spondylolysis, Short metacarpal, Dislocated wrist, Joint hy... OMIM:150250
Acro-Renal-Ocular Syndrome
Hypoplasia of the ulna, Abnormal thumb morphology, Aganglionic megacolon, Radial club hand, Triph... ORPHA:959
Ehlers-Danlos Syndrome, Classic-Like, 2
Osteopenia, Generalized joint hypermobility, Cervical C2/C3 vertebral fusion, Hammertoe, Squared ... OMIM:618000
Klippel-Feil Syndrome 4, Autosomal Recessive, With Nemaline Myopathy And Facial Dysmorphism
Cervical C2/C3 vertebral fusion, Thoracolumbar scoliosis, Flexion contracture, Acetabular dysplas... OMIM:616549
Microcephaly, Short Stature, And Limb Abnormalities
Hypoplasia of the radius, Clinodactyly of the 5th finger, Patellar hypoplasia, Dislocated radial ... OMIM:617604
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Fused cervical vertebrae, Abnormal hip bone morphology, Hyperlordosis, Kyphosis, Short neck ORPHA:2522
Split-Hand/Foot Malformation With Long Bone Deficiency 1
Aplasia of the 3rd finger, Short hallux, Split hand, Absent tibia, Hand monodactyly, Split foot, ... OMIM:119100
Arnold-Chiari Malformation Type I
Abnormality of the vestibulocochlear nerve, Abnormality of the twelfth cranial nerve, Stiff neck,... ORPHA:268882
Caudal Regression Syndrome
Aplasia/Hypoplasia of the sacrum, Abnormal iliac wing morphology, Scoliosis, Abnormal pelvic gird... ORPHA:3027
Limitation of knee mobility, Intervertebral disk degeneration, Arthritis, Arthropathy, Kyphosis, ... OMIM:203500
Robinow Syndrome, Autosomal Recessive 1
Hypoplastic sacrum, Radial deviation of finger, Mesomelic arm shortening, Dislocated radial head,... OMIM:268310
Mayer-Rokitansky-Küster-Hauser Syndrome
Endometriosis, Abnormal form of the vertebral bodies, Vertebral segmentation defect, Dyspareunia,... ORPHA:3109
Frontometaphyseal Dysplasia
Limited elbow movement, Limitation of knee mobility, Dislocated radial head, Wrist flexion contra... ORPHA:1826
Otopalatodigital Syndrome Type 2
Fibular aplasia, Preaxial polydactyly, Tarsal synostosis, Abnormal metacarpal morphology, Short h... ORPHA:90652
Sifrim-Hitz-Weiss Syndrome
Fused cervical vertebrae, Gait imbalance, Short clavicles, Flat acetabular roof, Short femoral ne... OMIM:617159
Patella Aplasia-Hypoplasia
Patellar aplasia, Patellar hypoplasia OMIM:168860
Koolen-De Vries Syndrome
Scoliosis, Vertebral segmentation defect, Kyphosis, Arachnodactyly, Joint hypermobility, Hip disl... ORPHA:96169
Mosaic Trisomy 20
Fused cervical vertebrae, Scoliosis, Vertebral segmentation defect, Kyphosis, Spinal canal stenos... ORPHA:1724
Gorlin Syndrome
Abnormal vertebral morphology, Vertebral wedging, Scoliosis, Hemivertebrae, Arachnodactyly, Brach... ORPHA:377
Duane-Radial Ray Syndrome
Hypoplasia of the ulna, Hypoplasia of the radius, Preaxial polydactyly, Aganglionic megacolon, Fu... OMIM:607323
Kbg Syndrome
Radial deviation of finger, Clinodactyly of the 5th finger, Thoracic kyphosis, Ulnar deviation of... OMIM:148050
Koolen-De Vries Syndrome
Sacral dimple, Spondylolisthesis, Scoliosis, Prominent fingertip pads, Kyphosis, Prominent metopi... OMIM:610443
Intellectual Developmental Disorder With Dysmorphic Facies And Ptosis
Joint hypermobility, Talipes equinovarus, Cervical C2/C3 vertebral fusion, Camptodactyly OMIM:617333
Fryns-Smeets-Thiry Syndrome
Scoliosis, Arachnodactyly, Patellar aplasia, Joint hypermobility, Hip dislocation ORPHA:2058
Lateral Meningocele Syndrome
Scoliosis, Wormian bones, Kyphosis, Biconcave vertebral bodies, Sclerosis of skull base, Joint hy... OMIM:130720
Craniofacial Dysmorphism, Skeletal Anomalies, And Impaired Intellectual Development Syndrome 1
Beaking of vertebral bodies, Sacral dimple, Hyperextensibility of the finger joints, Scoliosis, H... OMIM:213980
Basal Cell Nevus Syndrome 1
Kyphoscoliosis, Polydactyly, Short 4th metacarpal, Short distal phalanx of the thumb, Vertebral w... OMIM:109400
Nail-Patella Syndrome
Limited elbow extension, Clinodactyly of the 5th finger, Patellar hypoplasia, Talipes equinovarus... OMIM:161200
Myhre Syndrome
Short finger, Radial deviation of finger, Enlarged vertebral pedicles, Hypoplastic iliac wing, 2-... OMIM:139210
Thrombocytopenia-Absent Radius Syndrome
Femoral bowing, Broad thumb, Bilateral radial aplasia, Absent thumb, Aplasia/hypoplasia of the hu... OMIM:274000
Fanconi Anemia, Complementation Group I
Hypoplasia of the radius, Fused cervical vertebrae, Short 1st metacarpal, Optic nerve hypoplasia,... OMIM:609053
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Scoliosis, Hemivertebrae, Block vertebrae, Short neck, Supernumerary vertebrae, Vertebral fusion OMIM:271520
Intellectual Disability-Cardiac Anomalies-Short Stature-Joint Laxity Syndrome
Optic nerve hypoplasia, Abnormal optic disc morphology, Broad thumb, Short 5th finger, Overlappin... ORPHA:508498
Meier-Gorlin Syndrome 1
Absent sternal ossification, Delayed skeletal maturation, Joint hypermobility, Coxa valga, Genu v... OMIM:224690
Microphthalmia, Syndromic 3
Butterfly vertebrae, Optic nerve hypoplasia, Hemivertebrae, Vertebral hypoplasia, Optic nerve apl... OMIM:206900
Faciodigitogenital Syndrome, Autosomal Recessive
Clinodactyly of the 5th finger, Short foot, Camptodactyly, Metatarsus adductus, Syndactyly, Hyper... OMIM:227330
Roberts Syndrome
Hypoplasia of the radius, Radial deviation of finger, Mesomelic arm shortening, Proximal placemen... ORPHA:3103
Shashi-Pena Syndrome
Cervical C2/C3 vertebral fusion, Scoliosis, Short metacarpal, Osteoporosis, Kyphosis, Accelerated... OMIM:617190
Apert Syndrome
Limited elbow movement, Lambdoidal craniosynostosis, Delayed epiphyseal ossification, Finger synd... OMIM:101200
Duane Retraction Syndrome
Hypoplasia of the radius, Triphalangeal thumb, Spina bifida occulta, Abnormal form of the vertebr... ORPHA:233
Mosaic Trisomy 8
Clinodactyly of the 5th finger, Scoliosis, Vertebral segmentation defect, Limitation of joint mob... ORPHA:96061
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Osteopenia, Fused cervical vertebrae, Osteolysis, Joint swelling, Osteomyelitis OMIM:612852
Meier-Gorlin Syndrome 5
Slender long bone, Prominent metopic ridge, Delayed skeletal maturation, Hypoplasia of the capita... OMIM:613805
Apert Syndrome
Optic atrophy, Aplasia/Hypoplasia of the thumb, Finger syndactyly, Vertebral segmentation defect,... ORPHA:87
Simpson-Golabi-Behmel Syndrome
Clinodactyly of the 5th finger, Short 2nd finger, Finger syndactyly, Scoliosis, Vertebral segment... ORPHA:373
9Q33.3Q34.11 Microdeletion Syndrome
Fixed elbow flexion, Patellar hypoplasia, Inability to walk, Bilateral coxa valga, Prominent meto... ORPHA:495818
Intellectual Developmental Disorder, Autosomal Dominant 52
Lumbar scoliosis, Cervical C2/C3 vertebral fusion, Lumbar hyperlordosis OMIM:617796
Genitopatellar Syndrome
Hypoplastic ilia, Hypoplastic ischia, Radioulnar synostosis, Hip contracture, Short palm, Patella... ORPHA:85201
Aicardi Syndrome
Optic atrophy, Butterfly vertebrae, Scoliosis, Block vertebrae, Optic disc coloboma, Hip dysplasi... ORPHA:50
Frontometaphyseal Dysplasia 2
Fused cervical vertebrae, Short metatarsal, Flared metaphysis, Dislocated radial head, Scoliosis,... OMIM:617137
Vertebral, Cardiac, Tracheoesophageal, Renal, And Limb Defects
Butterfly vertebrae, Fused cervical vertebrae, Spina bifida occulta OMIM:619227
Wolf-Hirschhorn Syndrome
Sacral dimple, Abnormal sternal ossification, Abnormal form of the vertebral bodies, Short hallux... OMIM:194190
Holt-Oram Syndrome
Cervical C2/C3 vertebral fusion, Proximal placement of thumb, Aplasia of the 1st metacarpal, 1-2 ... OMIM:142900
Aicardi Syndrome
Optic atrophy, Butterfly vertebrae, Proximal placement of thumb, Scoliosis, Hemivertebrae, Block ... OMIM:304050
Meier-Gorlin Syndrome 4
Genu recurvatum, Delayed skeletal maturation, Patellar aplasia, Slender long bone OMIM:613804
Robinow Syndrome
Kyphoscoliosis, Mesomelic arm shortening, Scoliosis, Hemivertebrae, Mesomelia, Bifid distal phala... ORPHA:97360
Rothmund-Thomson Syndrome Type 2
Finger symphalangism, Osteopenia, Abnormal ulnar metaphysis morphology, Aplasia/hypoplasia involv... ORPHA:221016
Baller-Gerold Syndrome
Limited elbow movement, Carpal bone aplasia, Optic nerve hypoplasia, Oligodactyly, Short humerus,... OMIM:218600
Meier-Gorlin Syndrome 2
Tracheomalacia, Slender long bone, Camptodactyly, Delayed skeletal maturation, Patellar aplasia, ... OMIM:613800
Rothmund-Thomson Syndrome Type 1
Finger symphalangism, Osteopenia, Abnormal ulnar metaphysis morphology, Premature ovarian insuffi... ORPHA:221008
Penoscrotal Transposition
Patellar aplasia, Clinodactyly of the 5th finger ORPHA:2842
Chromosome 16P13.3 Duplication Syndrome
Rocker bottom foot, Proximal placement of hallux, Sacral dimple, Proximal placement of thumb, San... OMIM:613458
Chops Syndrome
Optic atrophy, Cervical C2/C3 vertebral fusion, Brachydactyly, Tracheomalacia OMIM:616368
Thakker-Donnai Syndrome
Short neck, Hemivertebrae, Cervical C2/C3 vertebral fusion ORPHA:1780
Cardiospondylocarpofacial Syndrome
Cone-shaped epiphysis, Tarsal synostosis, Fused cervical vertebrae, Scoliosis, Short foot, Fusion... OMIM:157800
Meier-Gorlin Syndrome 3
Patellar hypoplasia, Talipes equinovarus, Tracheomalacia, Absent sternal ossification, Aplasia/Hy... OMIM:613803
Recombinant 8 Syndrome
Camptodactyly of finger, Scoliosis, Patellar aplasia, Clinodactyly of the 5th finger ORPHA:96167
Ear-Patella-Short Stature Syndrome
Clinodactyly of the 5th finger, Slender long bone, Abnormal epiphysis morphology, Delayed skeleta... ORPHA:2554
Heterotaxy, Visceral, 1, X-Linked
Short long bone, Bilateral talipes equinovarus, Congenital hip dislocation, Block vertebrae, Abse... OMIM:306955
Cognitive Impairment-Coarse Facies-Heart Defects-Obesity-Pulmonary Involvement-Short Stature-Skeletal Dysplasia Syndrome
Hip subluxation, Abnormal vertebral morphology, Fibular hypoplasia, Cervical C2/C3 vertebral fusi... ORPHA:444077
Meier-Gorlin Syndrome 6
Sandal gap, Tracheobronchomalacia, Delayed skeletal maturation, Short middle phalanx of finger, P... OMIM:616835
Agammaglobulinemia-Microcephaly-Craniosynostosis-Severe Dermatitis Syndrome
Fused cervical vertebrae, Cleft vertebral arch, Coronal craniosynostosis, Arachnodactyly, Contrac... ORPHA:83617
Genitopatellar Syndrome
Scoliosis, Inferior pubic ramus hypoplasia, Congenital hip dislocation, Hypoplastic ischia, Radio... OMIM:606170
Osteogenesis Imperfecta
Vertebral compression fracture, Abnormal form of the vertebral bodies, Enlarged vertebral pedicle... ORPHA:666
Elsahy-Waters Syndrome
Cervical C2/C3 vertebral fusion, Cutaneous finger syndactyly, Increased cup-to-disc ratio, Shorte... OMIM:211380
Generalized Arterial Calcification Of Infancy
Stippled calcification of the elbow, Hypophosphatemic rickets, Fused cervical vertebrae, Abnormal... ORPHA:51608
Craniofacial Microsomia 1
Genu valgum, Scoliosis, Hemivertebrae, Vertebral hypoplasia, Partial duplication of thumb phalanx... OMIM:164210
Vertical Talus, Congenital
Rocker bottom foot, Arthritis, Equinus calcaneus, Calcaneovalgus deformity OMIM:192950


Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxd10

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxd10.

No publications found that use IMPC mice or data for Hoxd10.

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All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hoxd10tm413647(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Hoxd10tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

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