IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Gstm1 by phenotypic similarity.
||Elevated circulating catecholamine level, Paraganglioma||OMIM:618464|
||Glomus jugular tumor, Elevated circulating catecholamine level, Glomus tympanicum paraganglioma, ...||OMIM:168000|
||Glomus jugular tumor, Elevated circulating catecholamine level, Chemodectoma, Paraganglioma, Extr...||OMIM:605373|
|Pure Autonomic Failure||
||Abnormality of circulating catecholamine level||ORPHA:441|
|Von Hippel-Lindau Disease||
||Pancreatic endocrine tumor, Elevated circulating catecholamine level, Pancreatic islet cell adeno...||ORPHA:892|
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
This service may be affected by the Covid-19 pandemic. See how
|MGI Allele||Allele Type||Produced|
|Gstm1tm1e(EUCOMM)Hmgu||Targeted, non-conditional allele||ES Cells|
|Gstm1tm1a(EUCOMM)Hmgu||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|
Get highlights of the most important data releases, news and events, delivered straight to your email inboxSubscribe to newsletter