Genes Phenotypes

Gene: Fbn2

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Name
fibrillin 2
MGI ID
MGI:95490
Synonyms
Sne sy Fib-2
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (22) Measurements chart (195) All data table (297)
Expression & images (0) Disease models (0) Order (1)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged heart Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
prolonged QT interval Fbn2em1(IMPC)Rbrc HOM Early adult 7.45×10-06
increased large unstained cell number Fbn2em1(IMPC)Rbrc HOM Early adult 9.12×10-05
abnormal gait Fbn2em1(IMPC)Rbrc HOM Early adult 3.98×10-06
abnormal brain morphology Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
decreased grip strength Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
decreased lean body mass Fbn2em1(IMPC)Rbrc HOM Early adult 3.51×10-10
corneal opacity Fbn2em1(IMPC)Rbrc HOM Early adult 3.49×10-11
abnormal kidney morphology Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
abnormal optic disk morphology Fbn2em1(IMPC)Rbrc HOM Early adult 5.15×10-05
improved glucose tolerance Fbn2em1(IMPC)Rbrc HOM Early adult 2.55×10-05
corneal vascularization Fbn2em1(IMPC)Rbrc HOM Early adult 4.32×10-06
abnormal liver morphology Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
abnormal eye morphology Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
decreased total body fat amount Fbn2em1(IMPC)Rbrc HOM Early adult 2.12×10-05
abnormal heart morphology Fbn2em1(IMPC)Rbrc HOM Early adult 0.00
abnormal skin morphology Fbn2em1(IMPC)Rbrc HOM Early adult 3.98×10-06
abnormal digit morphology Fbn2em1(IMPC)Rbrc HOM Early adult 5.02×10-15
decreased body length Fbn2em1(IMPC)Rbrc HOM Early adult 4.76×10-10
abnormal tail morphology Fbn2em1(IMPC)Rbrc HOM Early adult 2.59×10-06
abnormal nail morphology Fbn2em1(IMPC)Rbrc HOM Early adult 5.02×10-15
abnormal autopod morphology Fbn2em1(IMPC)Rbrc HOM Early adult 5.21×10-15

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 Expression

Expression data not available

 Associated Images

Combined SHIRPA and Dysmorphology
20 Images
Eye Morphology: Images Slit Lamp
20 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
Gross Pathology and Tissue Collection
72 Images

 Disease Models

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MGI Allele Allele Type Produced
Fbn2em1(IMPC)Rbrc Indel causing a Frameshift Mutation Mice