Col9a2 | collagen, type IX, alpha 2
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Hearing/vestibular/ear Nervous system Behavior/neurological Skeleton
13 No significant impact
5 Not tested
Data collections
Gene metrics:15Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
abnormal femur morphology | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.51x10-14 | ||
increased circulating alkaline phosphatase level | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.83x10-5 | ||
decreased prepulse inhibition | 2 supporting datasets | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.44x10-9 | ||
tremors | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.21x10-6 | ||
abnormal humerus morphology | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.61x10-14 | ||
abnormal ulna morphology | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.57x10-14 | ||
short tibia | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.54x10-10 | ||
abnormal joint morphology | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.61x10-14 | ||
abnormal auditory brainstem response | 5 supporting datasets | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.63x10-7 | ||
abnormal pelvic girdle bone morphology | 1 supporting dataset | Col9a2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.95x10-8 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 50% (1/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | 50% (1/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
No external links available for Col9a2.
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Col9a2tm1(NCOM)Cmhd | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Col9a2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Col9a2tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Col9a2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |