Vsig8 | V-set and immunoglobulin domain containing 8

GeneMGI:3642995Synonyms: EG240916

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Cardiovascular system

14 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
42Embryo tissues

Phenotypes

shortened ST segment1 supporting datasetVsig8tm1.1(KOMP)MbphomozygoteEarly adult1.14x10-5 
increased heart weight1 supporting datasetVsig8tm1.1(KOMP)MbphomozygoteEarly adult5.14x10-5 
increased circulating potassium level1 supporting datasetVsig8tm1.1(KOMP)MbphomozygoteEarly adult1.22x10-5 
decreased circulating glucose level1 supporting datasetVsig8tm1.1(KOMP)MbphomozygoteEarly adult6.05x10-5 
decreased blood urea nitrogen level1 supporting datasetVsig8tm1.1(KOMP)MbphomozygoteEarly adult2.23x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Vsig8tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
mouse
Vsig8tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Vsig8tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Vsig8tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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