Gene: Shank1

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Name
SH3 and multiple ankyrin repeat domains 1
MGI ID
MGI:3613677
Synonyms
N/A
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
impaired cued conditioning behavior Shank1em1(IMPC)Mbp HOM   Early adult 9.16×10-05
abnormal liver morphology Shank1em1(IMPC)Mbp HOM Early adult 0.00
improved glucose tolerance Shank1em1(IMPC)Mbp HOM Early adult 5.45×10-06
increased mean corpuscular hemoglobin concentration Shank1em1(IMPC)Mbp HOM Early adult 3.10×10-05
decreased circulating alanine transaminase level Shank1em1(IMPC)Mbp HOM Late adult 2.17×10-05
small liver Shank1em1(IMPC)Mbp HOM Early adult 0.00
decreased lean body mass Shank1em1(IMPC)Mbp HOM Early adult 1.08×10-06
increased total body fat amount Shank1em1(IMPC)Mbp HOM Early adult 3.05×10-07
decreased eosinophil cell number Shank1em1(IMPC)Mbp HOM Early adult 4.70×10-07
abnormal spleen morphology Shank1em1(IMPC)Mbp HOM Late adult 0.00
decreased startle reflex Shank1em1(IMPC)Mbp HOM Early adult 2.83×10-06
decreased body weight Shank1em1(IMPC)Mbp HOM Late adult 4.57×10-09
abnormal skin morphology Shank1em1(IMPC)Mbp HOM Late adult 0.00
increased lymphocyte cell number Shank1em1(IMPC)Mbp HOM Early adult 2.21×10-05
decreased freezing behavior Shank1em1(IMPC)Mbp HOM Early adult 2.34×10-07
enlarged spleen Shank1em1(IMPC)Mbp HOM Late adult 0.00
decreased circulating cholesterol level Shank1em1(IMPC)Mbp HOM Late adult 4.85×10-05
abnormal liver morphology Shank1em1(IMPC)Mbp HOM Late adult 0.00
cataract Shank1em1(IMPC)Mbp HOM Early adult 3.31×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
30 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Shank1em1(IMPC)Mbp Exon Deletion Mice, Tissue
Shank1tm39541(L1L2_gt2) Targeting vectors

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