Gene Summary

Name:
trace amine-associated receptor 8C
Synonyms:
N/A

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal eye morphology Taar8cem1(IMPC)Mbp HOM Early adult 0.00
anophthalmia Taar8cem1(IMPC)Mbp HOM Early adult 0.00
abnormal skin morphology Taar8cem1(IMPC)Mbp HOM Early adult 0.00
small liver Taar8cem1(IMPC)Mbp HOM Early adult 0.00
thick skin Taar8cem1(IMPC)Mbp HOM Early adult 0.00
abnormal liver morphology Taar8cem1(IMPC)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Taar8c mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Taar8c by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Microphthalmia-Ankyloblepharon-Intellectual Disability Syndrome
Anophthalmia, Microphthalmia ORPHA:85275
Microphthalmia, Isolated 1
Anophthalmia, Microphthalmia OMIM:251600
Microphthalmia, Isolated, With Coloboma 10
Anophthalmia, Microphthalmia OMIM:616428
Microphthalmia, Isolated, With Coloboma 5
Anophthalmia, Bilateral microphthalmos, Microphthalmia OMIM:611638
Dextrocardia With Unusual Facies And Microphthalmia
Anophthalmia, Microphthalmia OMIM:221950
Microphthalmia, Syndromic 12
Anophthalmia, Microphthalmia OMIM:615524
Microphthalmia, Isolated 3
Anophthalmia, Microphthalmia OMIM:611038
Fryns Microphthalmia Syndrome
Anophthalmia, Microphthalmia OMIM:600776
Meckel Syndrome, Type 8
Anophthalmia, Microphthalmia OMIM:613885
Anencephaly 2
Anophthalmia OMIM:619452
Oculocerebrocutaneous Syndrome
Anophthalmia, Microphthalmia OMIM:164180
Matthew-Wood Syndrome
Microphthalmia, Annular pancreas, Aplasia/Hypoplasia of the pancreas, Anophthalmia, Abnormal sple... ORPHA:2470
Manitoba Oculotrichoanal Syndrome
Anophthalmia, Microphthalmia OMIM:248450
Early-Onset Epileptic Encephalopathy-Cortical Blindness-Intellectual Disability-Facial Dysmorphism Syndrome
Anophthalmia ORPHA:411986
Trisomy 13
Anophthalmia, Microphthalmia, Aplasia/Hypoplasia of the iris ORPHA:3378
Cockayne Syndrome Type 2
Anophthalmia, Hepatomegaly ORPHA:90322
Anophthalmia Plus Syndrome
Anophthalmia ORPHA:1104
Microphthalmia With Limb Anomalies
Anophthalmia, Microphthalmia OMIM:206920
Cerebrooculonasal Syndrome
Anophthalmia ORPHA:66625
Hydrolethalus
Anophthalmia, Microphthalmia ORPHA:2189
Solitary Median Maxillary Central Incisor
Anophthalmia, Microphthalmia OMIM:147250
Microphthalmia/Coloboma And Skeletal Dysplasia Syndrome
Anophthalmia, Microphthalmia OMIM:615877
Microphthalmia With Brain And Digit Anomalies
Anophthalmia, Microphthalmia ORPHA:139471
Microphthalmia, Syndromic 5
Anophthalmia, Optic nerve hypoplasia, Microphthalmia OMIM:610125
Microgastria-Limb Reduction Defects Association
Asplenia, Anophthalmia, Splenogonadal fusion, Absent gallbladder, Biliary tract abnormality OMIM:156810
Anophthalmia/Microphthalmia-Esophageal Atresia Syndrome
Anophthalmia, Microphthalmia ORPHA:77298
Oculotrichoanal Syndrome
Anophthalmia, Microphthalmia ORPHA:2717
Walker-Warburg Syndrome
Anophthalmia, Microphthalmia ORPHA:899
Microphthalmia, Syndromic 3
Anophthalmia, Optic nerve hypoplasia, Microphthalmia OMIM:206900
Cockayne Syndrome Type 1
Elevated hepatic transaminase, Hepatomegaly, Anophthalmia ORPHA:90321
Meckel Syndrome
Microphthalmia, Pancreatic cysts, Asplenia, Congenital hepatic fibrosis, Anophthalmia, Aplasia/Hy... ORPHA:564
Microphthalmia, Syndromic 9
Anophthalmia, Bilateral microphthalmos, Hypoplastic spleen, Multilobulated spleen OMIM:601186
Trisomy 1Q
Anophthalmia ORPHA:261344
Microgastria-Limb Reduction Defect Syndrome
Anophthalmia, Abnormality of the spleen, Microphthalmia, Hepatomegaly ORPHA:2538
Holoprosencephaly
Anophthalmia, Abnormality of the spleen, Microphthalmia ORPHA:2162
Fibular Hemimelia
Anophthalmia ORPHA:93323
Anophthalmia-Megalocornea-Cardiopathy-Skeletal Anomalies Syndrome
Anophthalmia, Aniridia ORPHA:1101
Vacterl With Hydrocephalus
Anophthalmia, Microphthalmia ORPHA:3412
Hyposmia-Nasal And Ocular Hypoplasia-Hypogonadotropic Hypogonadism Syndrome
Anophthalmia, Microphthalmia ORPHA:2250
Cerebrooculonasal Syndrome
Anophthalmia OMIM:605627
Joubert Syndrome 21
Anophthalmia OMIM:615636
Craniofacial Microsomia
Anophthalmia, Microphthalmia OMIM:164210
14Q22Q23 Microdeletion Syndrome
Anophthalmia, Optic nerve aplasia ORPHA:264200
Holoprosencephaly 9
Anophthalmia, Optic nerve hypoplasia, Microphthalmia OMIM:610829
Microcephaly-Lymphedema-Chorioretinopathy Syndrome
Anophthalmia, Microphthalmia ORPHA:2526
Microphthalmia With Linear Skin Defects Syndrome
Anophthalmia, Microphthalmia ORPHA:2556
Proboscis Lateralis
Anophthalmia, Optic nerve hypoplasia, Microphthalmia ORPHA:141099
Charge Syndrome
Anophthalmia, Microphthalmia ORPHA:138
Focal Dermal Hypoplasia
Anophthalmia, Microphthalmia, Aniridia OMIM:305600
Fraser Syndrome 1
Anophthalmia, Bilateral microphthalmos OMIM:219000
Microphthalmia, Syndromic 2
Anophthalmia, Microphthalmia OMIM:300166
Charge Syndrome
Anophthalmia, Webbed neck, Unilateral microphthalmos, Microphthalmia OMIM:214800
Fraser Syndrome
Anophthalmia, Microphthalmia ORPHA:2052
Microphthalmia With Limb Anomalies
True anophthalmia, Microphthalmia ORPHA:1106
Branchiooculofacial Syndrome
Anophthalmia, Microphthalmia OMIM:113620
Microphthalmia, Syndromic 6
Anophthalmia, Microphthalmia OMIM:607932
Microphthalmia, Syndromic 1
Anophthalmia, Webbed neck, Microphthalmia OMIM:309800

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Taar8c

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Taar8c.

No publications found that use IMPC mice or data for Taar8c.

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MGI Allele Allele Type Produced
Taar8cem1(IMPC)Mbp Whole-gene deletion Mice, Tissue

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