Genes Phenotypes

Gene: Ago1

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Name
argonaute RISC catalytic subunit 1
MGI ID
MGI:2446630
Synonyms
argonaute 1 Eif2c1
Viability
Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (150) All data table (270)
Expression & images (45) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Ago1tm1a(KOMP)Wtsi HOM Early adult 1.20×10-07
abnormal behavior Ago1tm1a(KOMP)Wtsi HOM Early adult 1.89×10-05
hyperactivity Ago1tm1a(KOMP)Wtsi HOM Early adult 9.33×10-05
preweaning lethality, incomplete penetrance Ago1tm1a(KOMP)Wtsi HOM Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ago1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ago1tm36769(L1L2_Bact_P) Targeting vectors

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