Gene: Ago1

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argonaute RISC catalytic subunit 1
argonaute 1 Eif2c1
Embryo viewer
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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Ago1tm1a(KOMP)Wtsi HOM   Early adult 2.79×10-05
increased circulating calcium level Ago1tm1a(KOMP)Wtsi HOM   Early adult 3.24×10-05
decreased mean corpuscular hemoglobin Ago1tm1a(KOMP)Wtsi HOM Early adult 2.24×10-05
abnormal behavior Ago1tm1a(KOMP)Wtsi HOM   Early adult 6.17×10-05
preweaning lethality, incomplete penetrance Ago1tm1a(KOMP)Wtsi HOM   Early adult 0.00
thrombocytopenia Ago1tm1a(KOMP)Wtsi HOM Early adult 3.00×10-05

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Viewing: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/511)  (1/2) N/A
Aorta 2 No  (1/499) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (4/504)  (2/2) N/A
Brainstem 2 No  (2/498) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/507)  (1/2) N/A
Cerebellum 2 No  (3/499) N/A
Cerebral cortex 2 No  (2/510) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/486) N/A
Hippocampus 2 No  (3/494) N/A
Hypothalamus 2 No  (2/492) N/A
Kidney 2 No  (18/493) N/A
Large intestine 2 No  (10/483) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/505) N/A
Lung 2 No  (1/505) N/A
Lymph node 2 No  (1/522) N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/483) N/A
Ovary 2 No N/A
Oviduct 2 No N/A
Pancreas 2 No  (4/493) N/A
Parathyroid gland 2 No  (1/477) N/A
Peripheral nervous system 2 No  (2/501)  (2/2) N/A
Peyer's patch 2 No  (1/155) N/A
Pituitary gland 2 No  (1/509) N/A
Prostate gland 2 No  (11/507) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (7/504) N/A
Spinal cord 2 No  (3/492)  (2/2) N/A
Spleen 2 No  (3/499) N/A
Stomach 2 No  (12/496) N/A
Striatum 2 No  (2/505) N/A
Testis 2 No  (6/490) N/A
Thymus 2 No  (1/502) N/A
Thyroid gland 2 No  (13/498) N/A
Trachea 2 No  (2/504) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Ago1tm36769(L1L2_Bact_P) Targeting vectors
Ago1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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