Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

RNA binding motif protein 15

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Not Significant
Not tested


The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Rbm15 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Rbm15 by phenotypic similarity.

Disease Similarity of
Matching phenotypes Source
Myeloproliferative Syndrome, Transient
Leukocytosis, Transient myeloproliferative syndrome OMIM:159595
Myeloproliferative Disorder, Chronic, With Eosinophilia
Myeloproliferative disorder, Eosinophilia, Malignant eosinophil proliferation OMIM:131440
Lymphoblastic Leukemia, Acute, With Lymphomatous Features
T-cell acute lymphoblastic leukemias, Acute lymphoblastic leukemia, Lymphoma OMIM:247640
Erythroleukemia, Familial, Susceptibility To
Erythroid hyperplasia, Leukemia, Anemia, Splenomegaly, Acute myeloid leukemia, Thrombocytopenia, ... OMIM:133180
Macroglobulinemia, Waldenstrom, Susceptibility To, 1
Leukemia, Monoclonal immunoglobulin M proteinemia, Impaired lymphocyte transformation with phytoh... OMIM:153600
Glioma Susceptibility 9
Leukemia, Glioma, Astrocytoma OMIM:616568
Juvenile Myelomonocytic Leukemia
Juvenile myelomonocytic leukemia OMIM:607785
Monosomy 7 Myelodysplasia And Leukemia Syndrome 1
Acute myeloid leukemia, Myelodysplasia, Increased mean corpuscular volume, Thrombocytopenia OMIM:252270
Myeloproliferative Disease, Autosomal Recessive
Myeloproliferative disorder OMIM:254700
Neutropenia, Severe Congenital, 5, Autosomal Recessive
Neutropenia, Leukopenia, Anemia, Splenomegaly, Extramedullary hematopoiesis, Thrombocytopenia OMIM:615285
Neutropenia, Nonimmune Chronic Idiopathic, Of Adults
Acute myeloid leukemia, Neutropenia OMIM:607847
Leukemia, Acute, X-Linked
Acute leukemia OMIM:308960
Leukemia, Acute Monocytic
Acute monocytic leukemia OMIM:151380
Leukemia, Acute Lymphoblastic
Acute lymphoblastic leukemia OMIM:613065
Leukemia, Acute Myeloid
Acute myeloid leukemia OMIM:601626
Fanconi Anemia, Complementation Group G
Myelodysplasia, Neutropenia, Leukemia, Anemia, Thrombocytopenia OMIM:614082
Mismatch Repair Cancer Syndrome 2
T-cell acute lymphoblastic leukemias, Glioblastoma multiforme, Colon cancer OMIM:619096
Leukemia, Acute Myelocytic, With Polyposis Coli And Colon Cancer
Acute myeloid leukemia, Adenomatous colonic polyposis, Colon cancer OMIM:246470
Monosomy 7 Myelodysplasia And Leukemia Syndrome 2
Neutropenia, Increased mean corpuscular volume, Myelodysplasia, Anemia, Acute myeloid leukemia, P... OMIM:619041
Neutropenia, Severe Congenital, 1, Autosomal Dominant
Thrombocytosis, Neutropenia, Monocytosis, Congenital agranulocytosis, Anemia, Acute monocytic leu... OMIM:202700
Myeloproliferative/Lymphoproliferative Neoplasms, Familial (Multiple Types), Susceptibility To
Myelodysplasia, Leukopenia, Monocytosis, Refractory anemia, Lymphoma, Acute myeloid leukemia OMIM:616871
Alpha-Thalassemia-Myelodysplastic Syndrome
Neutropenia, Myelodysplasia, Acute leukemia, Splenomegaly, Microcytic anemia, Thrombocytopenia, H... ORPHA:231401
Nut Midline Carcinoma
Neuroblastoma, Pancreatic squamous cell carcinoma, Leukemia, Oropharyngeal squamous cell carcinom... ORPHA:443167
Ras-Associated Autoimmune Leukoproliferative Disorder
Neutropenia, Monocytosis, Leukemia, Lymphoproliferative disorder, Lymphoma, Splenomegaly, Autoimm... OMIM:614470
Li-Fraumeni Syndrome
Ovarian neoplasm, Acute lymphoblastic leukemia, Thyroid carcinoma, Astrocytoma, Choriocarcinoma, ... ORPHA:524
Immunodeficiency 21
Abnormal natural killer cell morphology, Neutropenia, Myelodysplasia, Lymphopenia, Myeloid leukem... OMIM:614172
Li-Fraumeni Syndrome
Adrenocortical carcinoma, Prostate neoplasm, Choriocarcinoma, Acute leukemia, Lung adenocarcinoma... OMIM:151623
Pulmonary Fibrosis And/Or Bone Marrow Failure, Telomere-Related, 2
Leukemia, Myeloid leukemia, Aplastic anemia, Pancytopenia OMIM:614743
Generalized Eruptive Histiocytosis
Leukemia, Hypereosinophilia, Histiocytosis ORPHA:157991
Myelodysplastic Syndrome Associated With Isolated Del(5Q) Chromosome Abnormality
Thrombocytosis, Macrocytic anemia, Myelodysplasia, Leukopenia, Multiple lineage myelodysplasia, E... ORPHA:86841
Immunodeficiency, Common Variable, 13
Pancytopenia, B lymphocytopenia, Acute lymphoblastic leukemia OMIM:616873
Hypereosinophilic Syndrome, Idiopathic
Myeloproliferative disorder, Eosinophilia, Splenomegaly OMIM:607685
Unclassified Myelodysplastic Syndrome
Leukocytosis, Acute myeloid leukemia, Myelodysplasia, Multiple lineage myelodysplasia ORPHA:98827
Acquired Hemophagocytic Lymphohistiocytosis Associated With Malignant Disease
Acute lymphoblastic leukemia, Neutropenia, Splenomegaly, Hepatosplenomegaly, Pancytopenia, Nephro... ORPHA:158057
Leukemia, Chronic Lymphocytic, Susceptibility To, 2
Chronic lymphatic leukemia OMIM:109543
Leukemia, Chronic Lymphocytic
Chronic lymphatic leukemia OMIM:151400
Platelet Disorder, Familial, With Associated Myeloid Malignancy
Neuroblastoma, Myelodysplasia, Abnormal dense granule content, Lymphoma, Acute myeloid leukemia, ... OMIM:601399
N Syndrome
Leukemia, Neoplasm OMIM:310465
Lymphedema, Primary, With Myelodysplasia
Leukemia, Myelodysplasia, Pancytopenia OMIM:614038
Storage Pool Platelet Disease
Decreased mean platelet volume, Myelodysplasia, Acute leukemia OMIM:185050
Acquired Idiopathic Sideroblastic Anemia
Leukocytosis, Thrombocytosis, Neutropenia, Normocytic anemia, Megaloblastic erythroid hyperplasia... ORPHA:75564
Chronic Myeloid Leukemia
Thrombocytosis, Abnormal basophil morphology, Leukocytosis, Abnormal granulocyte morphology, Sple... ORPHA:521
Dohle Bodies And Leukemia
Acute myeloid leukemia, Anemia, Leukocyte inclusion bodies OMIM:223350
Neutropenia, Severe Congenital, 3, Autosomal Recessive
Acute lymphoblastic leukemia, Neutropenia, Myelodysplasia OMIM:610738
Leukemia, Chronic Myeloid
Ph-positive acute lymphoblastic leukemia, Chronic myelogenous leukemia OMIM:608232
Primary Erythromelalgia
Leukemia ORPHA:90026
Wt Limb-Blood Syndrome
Leukemia, Thrombocytopenia, Hypoplastic anemia, Pancytopenia OMIM:194350
Chromosome 14Q32 Duplication Syndrome, 700-Kb
Myeloid leukemia OMIM:616604
Ataxia-Pancytopenia Syndrome
Hypoplastic anemia, Neutropenia, Acute myelomonocytic leukemia, Anemia, Pancytopenia, Thrombocyto... OMIM:159550
Ataxia-Pancytopenia Syndrome
Hypoplastic anemia, Acute myelomonocytic leukemia, Splenomegaly, Abnormal macrophage morphology, ... ORPHA:2585
Cutaneous Neuroendocrine Carcinoma
Multiple myeloma, Lymphoid leukemia, Brain neoplasm, Basal cell carcinoma, Squamous cell carcinom... ORPHA:79140
Leukocyte Adhesion Deficiency, Type Iii
Leukocytosis, Anemia, Splenomegaly, Hepatosplenomegaly, Extramedullary hematopoiesis OMIM:612840
Myelocytic Leukemia-Like Syndrome, Familial, Chronic
Chronic myelogenous leukemia OMIM:600080
Primary Myelofibrosis
Leukocytosis, Thrombocytosis, Hemangioma, Anemia, Splenomegaly, Hepatosplenomegaly, Poikilocytosi... ORPHA:824
Mismatch Repair Cancer Syndrome 1
Neuroblastoma, Astrocytoma, Plexiform neurofibroma, Adenocarcinoma of the small intestine, Adenom... OMIM:276300
Acute Promyelocytic Leukemia
Acute promyelocytic leukemia OMIM:612376
Amed Syndrome, Digenic
Myelodysplasia, Leukopenia, Anemia, Acute myeloid leukemia, Thrombocytopenia OMIM:619151
Autosomal Dominant Severe Congenital Neutropenia
Acute lymphoblastic leukemia, Neutropenia, Myelodysplasia, Monocytosis, Leukemia, Hemangioma, Acu... ORPHA:486
Systemic Mastocytosis With Associated Hematologic Neoplasm
Leukocytosis, Chronic lymphatic leukemia, Normocytic anemia, Myelodysplasia, Multiple myeloma, No... ORPHA:98849
Fanconi Anemia, Complementation Group D1
T-cell acute lymphoblastic leukemias, Acute myeloid leukemia OMIM:605724
Pulmonary Fibrosis And/Or Bone Marrow Failure, Telomere-Related, 1
Myelodysplasia, Anemia, Myeloid leukemia, Pancytopenia, Aplastic anemia OMIM:614742
Osteopetrosis, Autosomal Recessive 2
Anemia, Hepatosplenomegaly, Extramedullary hematopoiesis, Pancytopenia, Thrombocytopenia OMIM:259710
Megalencephaly-Capillary Malformation-Polymicrogyria Syndrome
Leukemia, Nephroblastoma, Meningioma OMIM:602501
Essential Thrombocythemia
Myelodysplasia, Abnormal platelet morphology, Acute leukemia, Splenomegaly ORPHA:3318
Myeloproliferative disorder, Splenomegaly OMIM:254450
Immunodeficiency 36
Chronic lymphatic leukemia, B-cell lymphoma, Lymphopenia, Splenomegaly OMIM:616005
Aggressive Systemic Mastocytosis
Leukocytosis, Neutropenia, Thrombocytopenia, Leukemia, Anemia, Abnormal mast cell morphology, Hep... ORPHA:98850
Deafness-Lymphedema-Leukemia Syndrome
Leukocytosis, Acute leukemia, Splenomegaly, Myeloproliferative disorder, Thrombocytopenia, Abnorm... ORPHA:3226
Refractory Anemia With Excess Blasts
Leukocytosis, Abnormal mean corpuscular volume, Multiple lineage myelodysplasia, Acute myeloid le... ORPHA:86839
Prostate neoplasm, Imbalanced hemoglobin synthesis, Neoplasm of the lung, Neoplasia of the pleura... ORPHA:99867
Acute Panmyelosis With Myelofibrosis
Acute myelomonocytic leukemia, Splenomegaly, Acute myeloid leukemia, Lymphocytosis, Pancytopenia ORPHA:86843
Hereditary Spherocytosis
Anemia, Splenomegaly, Extramedullary hematopoiesis, Increased mean corpuscular hemoglobin concent... ORPHA:822
Acute Monoblastic/Monocytic Leukemia
Leukocytosis, Anemia, Hypochromic anemia, Lymphocytosis, Acute monocytic leukemia ORPHA:514
Beta-Thalassemia Intermedia
Leukocytosis, Erythroid hyperplasia, Hepatocellular carcinoma, Persistence of hemoglobin F, Splen... ORPHA:231222
Osteopetrosis, Autosomal Recessive 5
Anemia, Decreased osteoclast count, Splenomegaly, Extramedullary hematopoiesis, Pancytopenia, Thr... OMIM:259720
Chilblain Lupus
Chronic myelomonocytic leukemia ORPHA:90280
Autoimmune Hemolytic Anemia, Warm Type
Lymphoproliferative disorder, Chronic lymphatic leukemia, Autoimmune hemolytic anemia, Splenomegaly ORPHA:90033
Syndromic Recessive X-Linked Ichthyosis
Testicular seminoma, Acute leukemia ORPHA:281090
Leukemia, Lymphoma, Osteosarcoma, Pinealoma, Retinoblastoma, Ewing sarcoma OMIM:180200
Turcot Syndrome With Polyposis
Astrocytoma, Thyroid carcinoma, Adenomatous colonic polyposis, Leukemia, Brain neoplasm, Basal ce... ORPHA:99818
Osteopetrosis, Autosomal Recessive 3
Hepatosplenomegaly, Anemia, Extramedullary hematopoiesis OMIM:259730
Dominant Beta-Thalassemia
Hypochromic microcytic anemia, Hepatocellular carcinoma, Persistence of hemoglobin F, Splenomegal... ORPHA:231226
Pyoderma Gangrenosum
Myeloid leukemia, Myelodysplasia ORPHA:48104
Nasu-Hakola Disease
Acute leukemia ORPHA:2770
Beta-Thalassemia Major
Anisopoikilocytosis, Hypochromic microcytic anemia, Hepatocellular carcinoma, Splenomegaly, Persi... ORPHA:231214
Fgfr2-Related Bent Bone Dysplasia
Hepatosplenomegaly, Extramedullary hematopoiesis ORPHA:313855
Familial Thrombocytosis
Thrombocytosis, Myelodysplasia, Chronic myelogenous leukemia, Splenomegaly, Acute myeloid leukemia ORPHA:71493
Lig4 Syndrome
Pancytopenia, Leukocytosis, Lymphoma, Acute leukemia ORPHA:99812
Porphyria Due To Ala Dehydratase Deficiency
Myeloproliferative disorder, Abnormal erythrocyte enzyme level ORPHA:100924
Sweet Syndrome
Leukocytosis, Chronic lymphatic leukemia, Sterile abscess, Anemia, Neoplasm, Breast carcinoma, Ac... ORPHA:3243
Congenital Bile Acid Synthesis Defect Type 2
Extramedullary hematopoiesis ORPHA:79303
Acute leukemia, Chronic leukemia, Splenomegaly, Sarcoma, Mastocytosis ORPHA:98292
Fanconi Anemia, Complementation Group E
Neutropenia, Leukemia, Anemia, Reticulocytopenia, Pancytopenia, Thrombocytopenia OMIM:600901
Fanconi Anemia, Complementation Group A
Neutropenia, Leukemia, Anemia, Reticulocytopenia, Pancytopenia, Thrombocytopenia OMIM:227650
Diffuse Cutaneous Mastocytosis
Myeloproliferative disorder, Lymphocytosis, Abnormality of the spleen ORPHA:79456
Hodgkin lymphoma, Leukemia, Hypoplasia of the thymus, Lymphoma, Decreased proportion of CD4-posit... OMIM:208900
Shwachman-Diamond Syndrome
Chronic neutropenia, Macrocytic anemia, Neutropenia, Normocytic anemia, Leukopenia, Increased mea... ORPHA:811
Shwachman-Diamond Syndrome 1
Neutropenia, Myelodysplasia, Anemia, Persistence of hemoglobin F, Acute myeloid leukemia, Pancyto... OMIM:260400
Bloom Syndrome
Leukemia, Squamous cell carcinoma, Lymphoma OMIM:210900
Waldenström Macroglobulinemia
Normocytic anemia, Leukemia, Monoclonal immunoglobulin M proteinemia, Lymphoma, Splenomegaly, Abn... ORPHA:33226
Noonan Syndrome 6
Juvenile myelomonocytic leukemia OMIM:613224
Rhabdomyosarcoma, Leukemia, Leiomyosarcoma, Lymphoma, Ewing sarcoma, Osteosarcoma, Retinoblastoma... ORPHA:790
Down Syndrome
Acute megakaryocytic leukemia, Myeloproliferative disorder OMIM:190685
Fanconi Anemia, Complementation Group C
Neutropenia, Leukemia, Anemia, Reticulocytopenia, Pancytopenia, Thrombocytopenia OMIM:227645
Blackfan-Diamond Anemia
Thrombocytosis, Elevated red cell adenosine deaminase level, Neutropenia, Increased mean corpuscu... ORPHA:124
Rothmund-Thomson Syndrome Type 1
Neoplasm of the skin, Neutropenia, Myelodysplasia, Leukemia, Basal cell carcinoma, Anemia, Osteos... ORPHA:221008
Rothmund-Thomson Syndrome
Neoplasm of the skin, Neutropenia, Myelodysplasia, Leukemia, Basal cell carcinoma, Anemia, Squamo... ORPHA:2909
Rothmund-Thomson Syndrome Type 2
Neoplasm of the skin, Neutropenia, Myelodysplasia, Leukemia, Basal cell carcinoma, Anemia, Lympho... ORPHA:221016
Nijmegen Breakage Syndrome
Acute leukemia, Rhabdomyosarcoma, Neoplasm, Lymphoma, B-cell lymphoma, Thrombocytopenia, Glioma, ... ORPHA:647
Wiskott-Aldrich Syndrome
Neutropenia, Acute leukemia, Hypoplasia of the thymus, Chronic leukemia, Abnormal platelet morpho... ORPHA:906
Bloom Syndrome
Neoplasm of the skin, Acute lymphoblastic leukemia, Malignant genitourinary tract tumor, Myelodys... ORPHA:125
Polycythemia Vera
Myelodysplasia, Acute leukemia, Splenomegaly ORPHA:729
Tatton-Brown-Rahman Syndrome
Myeloid leukemia, Neuroendocrine neoplasm ORPHA:404443
Ataxia-Telangiectasia With Generalized Skin Pigmentation And Early Death
Leukemia OMIM:208910
Juvenile Xanthogranuloma
Myeloproliferative disorder ORPHA:158000
Legius Syndrome
Non-small cell lung carcinoma, Ovarian neoplasm, Vestibular Schwannoma, Desmoid tumors, Acute mon... ORPHA:137605
Fanconi Anemia, Complementation Group D2
Neutropenia, Leukemia, Anemia, Reticulocytopenia, Pancytopenia, Thrombocytopenia OMIM:227646
Congenital Factor Xiii Deficiency
Myeloid leukemia ORPHA:331
Neurofibromatosis Type 1
Neoplasm of the skin, Astrocytoma, Meningioma, Plexiform neurofibroma, Spinal neurofibromas, Neop... ORPHA:636
Bone Marrow Failure Syndrome 3
Pancytopenia, Acute myeloid leukemia, Aplastic anemia OMIM:617052
Myelodysplasia, Immunodeficiency, Facial Dysmorphism, Short Stature, And Psychomotor Delay
Anemia, Acute myeloid leukemia, Myelodysplasia, Neutropenia OMIM:601347
Tarp Syndrome
Extramedullary hematopoiesis ORPHA:2886
Greenberg Dysplasia
Hepatosplenomegaly, Extramedullary hematopoiesis OMIM:215140
Simple Cryoglobulinemia
Chronic lymphatic leukemia, Monoclonal immunoglobulin M proteinemia, B-cell lymphoma, Multiple my... ORPHA:91139
Idiopathic Hypereosinophilic Syndrome
Leukocytosis, Thrombocytosis, Myelodysplasia, Anemia, Splenomegaly, Myeloproliferative disorder, ... ORPHA:3260
Down Syndrome
Acute megakaryocytic leukemia ORPHA:870
Mosaic Variegated Aneuploidy Syndrome 1
Leukemia, Nephroblastoma, Rhabdomyosarcoma OMIM:257300
Dyskeratosis Congenita, X-Linked
Myelodysplasia, Hodgkin lymphoma, Leukopenia, Carcinoma, Anemia, Acute myeloid leukemia, Squamous... OMIM:305000
Noonan Syndrome 2
Leukemia OMIM:605275
Mosaic Variegated Aneuploidy Syndrome
Acute lymphoblastic leukemia, Myelodysplasia, Stomach cancer, Rhabdomyosarcoma, Neoplasm, Vaginal... ORPHA:1052
Dubowitz Syndrome
Neuroblastoma, Acute lymphoblastic leukemia, Aplastic anemia, Lymphoma OMIM:223370
Dubowitz Syndrome
Acute lymphoblastic leukemia, Anemia, Neoplasm, Lymphoma, Thrombocytopenia, Abnormality of neutro... ORPHA:235
17Q11 Microdeletion Syndrome
Pheochromocytoma, Myelodysplasia, Gastrointestinal stroma tumor, Rhabdomyosarcoma, Plexiform neur... ORPHA:97685
Lymphoid leukemia, Neoplasm ORPHA:1546
Coloboma, Congenital Heart Disease, Ichthyosiform Dermatosis, Mental Retardation, And Ear Anomalies Syndrome
Acute lymphoblastic leukemia OMIM:280000
Ellis Van Creveld Syndrome
Acute leukemia ORPHA:289
Microcephaly-Lymphedema-Chorioretinopathy Syndrome
Leukemia, Lymphoma ORPHA:2526
Schinzel-Giedion Syndrome
Ependymoma, Hepatoblastoma, Facial hemangioma, Teratoma, Myeloid leukemia, Nephroblastoma, Sacroc... ORPHA:798
Noonan Syndrome-Like Disorder With Or Without Juvenile Myelomonocytic Leukemia
Juvenile myelomonocytic leukemia OMIM:613563
Chime Syndrome
Acute leukemia ORPHA:3474
Noonan Syndrome 3
Juvenile myelomonocytic leukemia OMIM:609942
Aicardi-Goutières Syndrome
Enchondroma, Chronic lymphatic leukemia, Hepatosplenomegaly, Neonatal alloimmune thrombocytopenia ORPHA:51
Chronic Thromboembolic Pulmonary Hypertension
Myeloproliferative disorder, Neoplasm ORPHA:70591
Poland Syndrome
Neoplasm of the breast, Retinal hamartoma, Acute leukemia ORPHA:2911
Chronic Visceral Acid Sphingomyelinase Deficiency
Neoplasm of the liver, Splenomegaly, Acute promyelocytic leukemia, Hypersplenism, Autoimmune thro... ORPHA:77293
Leukocyte Adhesion Deficiency
Leukocytosis, Thrombocytosis, Polycythemia, Acute myeloid leukemia, Perianal abscess, Abnormality... ORPHA:2968
Rubinstein-Taybi Syndrome 1
Leukemia, Papillary cystadenoma of the epididymis, Capillary hemangioma, Neoplasm OMIM:180849
Noonan Syndrome 1
Neurofibrosarcoma, Juvenile myelomonocytic leukemia, Amegakaryocytic thrombocytopenia OMIM:163950
Sotos Syndrome
Neuroblastoma, Acute lymphoblastic leukemia, Astrocytoma, Cholesteatoma, Hemangioma, Neoplasm, Sa... ORPHA:821
Metaphyseal Chondromatosis With D-2-Hydroxyglutaric Aciduria
Cavernous hemangioma, Lymphangioma, Acute myelomonocytic leukemia, Cavernous hemangioma of the fa... ORPHA:99646


Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Rbm15

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Rbm15.

No publications found that use IMPC mice or data for Rbm15.

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MGI Allele Allele Type Produced
Rbm15tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Rbm15tm418084(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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