Gene: Grhl2

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Name
grainyhead like transcription factor 2
MGI ID
MGI:2182543
Synonyms
BOM 0610015A08Rik Tcfcp2l3 grainyheadlike clft3
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube morphology Grhl2em1(IMPC)Mbp HOM E9.5 0.00
embryonic growth retardation Grhl2em1(IMPC)Mbp HOM E15.5 0.00
abnormal optic vesicle formation Grhl2em1(IMPC)Mbp HOM E9.5 0.00
exencephaly Grhl2em1(IMPC)Mbp HOM E15.5 0.00
abnormal placenta morphology Grhl2em1(IMPC)Mbp HET E15.5 0.00
abnormal heart morphology Grhl2em1(IMPC)Mbp HOM E9.5 0.00
abnormal neural tube closure Grhl2em1(IMPC)Mbp HOM E9.5 0.00
abnormal forebrain development Grhl2em1(IMPC)Mbp HOM E9.5 0.00
abnormal midbrain development Grhl2em1(IMPC)Mbp HOM E9.5 0.00
abnormal hindbrain development Grhl2em1(IMPC)Mbp HOM E9.5 0.00
abnormal limb morphology Grhl2em1(IMPC)Mbp HOM E15.5 0.00
syndactyly Grhl2em1(IMPC)Mbp HOM E15.5 0.00
abnormal craniofacial morphology Grhl2em1(IMPC)Mbp HOM E15.5 0.00
abnormal abdominal wall morphology Grhl2em1(IMPC)Mbp HOM E15.5 0.00
abnormal neural tube morphology Grhl2em1(IMPC)Mbp HET E9.5 0.00
preweaning lethality, complete penetrance Grhl2em1(IMPC)Mbp HOM   Early adult 0.00
abnormal pericardium morphology Grhl2em1(IMPC)Mbp HOM E9.5 0.00
abnormal blood vessel morphology Grhl2em1(IMPC)Mbp HET E15.5 0.00
increased exploration in new environment Grhl2em1(IMPC)Mbp HET Early adult 4.20×10-12
abnormal head shape Grhl2em1(IMPC)Mbp HOM E15.5 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
60 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images

 Disease Models

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MGI Allele Allele Type Produced
Grhl2tm44874(L1L2_Pgk_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Grhl2em1(IMPC)Mbp Exon Deletion Mice, Tissue
Grhl2tm50612(L1L2_Bact_P) Targeting vectors

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