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Gene: Itga10 MGI:2153482

Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:

integrin, alpha 10

Synonyms:

N/A

Order Alleles

IMPC Data Collections

No Body Weight Data
No Embryo Imaging Data
No Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Itga10 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Itga10 (0 diseases)
Human diseases predicted to be associated with Itga10 (187 diseases)

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Itga10 by phenotypic similarity.

Disease	Matching phenotypes	Source
Upington Disease	Flattened femoral head, Broad femoral neck, Multiple enchondromatosis, Arthralgia of the hip	OMIM:191520
Hypoplastic Femurs And Pelvis	Hypoplastic pelvis, Short femur	OMIM:619545
Syndactyly Type 4	Triphalangeal thumb, Camptodactyly of finger, Short tibia, Foot polydactyly, Toe syndactyly, Hand...	ORPHA:93405
Rhizomelic Chondrodysplasia Punctata, Type 3	Epiphyseal stippling, Short humerus, Rhizomelia, Short femur	OMIM:600121
Genochondromatosis Type 1	Multiple enchondromatosis, Abnormality of the knee	ORPHA:85197
Mesomelic Dwarfism Of Hypoplastic Tibia And Radius Type	Short tibia, Hypoplasia of the radius, Pseudoarthrosis	OMIM:156230
Rhizomelic Dysplasia, Ain-Naz Type	Short femoral neck, Wide distal femoral metaphysis, Rhizomelia, Hip dysplasia, Short femur, Hypop...	OMIM:619598
Chondrodysplasia Punctata, Tibia-Metacarpal Type	Short tibia, Short 4th metacarpal, Short long bone, Epiphyseal stippling, Short 3rd metacarpal, S...	OMIM:118651
Acromesomelic Dysplasia 2C	Short tibia, Hypoplasia of the radius, Radial bowing, Cuboidal metacarpal, Hip dislocation, Hypop...	OMIM:201250
Tibia, Hypoplasia Or Aplasia Of, With Polydactyly	Triphalangeal thumb, Short tibia, Absent tibia, Preaxial polydactyly, Fibular duplication	OMIM:188740
Acromesomelic Dysplasia 2A	Short tibia, Short phalanx of finger, Aplasia/Hypoplasia involving the metacarpal bones, Hypoplas...	OMIM:200700
Fibular Aplasia, Tibial Campomelia, And Oligosyndactyly Syndrome	Short tibia, Foot oligodactyly, Hand oligodactyly, Syndactyly, Fibular aplasia, Tibial bowing	OMIM:246570
Acrocapitofemoral Dysplasia	Short tibia, Flared iliac wing, Short proximal phalanx of finger, Short femur, Enlargement of the...	OMIM:607778
Gollop-Wolfgang Complex	Aplasia/Hypoplasia of the tibia, Hand monodactyly, Bifid femur, Ectrodactyly, Aplasia/Hypoplasia ...	ORPHA:1986
Tibial Torsion, Bilateral Medial	Bowing of the legs, Tibial torsion	OMIM:188800
Acromesomelic Dysplasia, Grebe Type	Short tibia, Short toe, Aplasia/Hypoplasia of the thumb, Aplasia/Hypoplasia involving the metacar...	ORPHA:2098
Osebold-Remondini Syndrome	Short tibia, Short toe, Short phalanx of finger, Hypoplasia of the radius, Carpal synostosis, Hyp...	OMIM:112910
Langer Mesomelic Dysplasia	Short tibia, Broad ulna, Short femoral neck, Hypoplasia of the radius, Radial bowing, Micrognathi...	OMIM:249700
Ischiocoxopodopatellar Syndrome With Or Without Pulmonary Arterial Hypertension	Patellar hypoplasia, Patellar aplasia, Coxa vara, Patellar dislocation, Micrognathia, Flat capita...	OMIM:147891
Metaphyseal Anadysplasia 2	Genu varum, Metaphyseal irregularity, Short femoral neck, Bowing of the legs, Micromelia, Metaphy...	OMIM:613073
Metachondromatosis	Multiple enchondromatosis, Bowing of the long bones	OMIM:156250
Enchondromatosis, Multiple, Ollier Type	Multiple enchondromatosis, Abnormal long bone morphology	OMIM:166000
Mesomelic Dysplasia, Savarirayan Type	Short tibia, Abnormal foot morphology, Hip dislocation, Dislocated radial head, Talipes equinoval...	OMIM:605274
Epiphyseal Dysplasia, Multiple, With Severe Proximal Femoral Dysplasia	Broad femoral neck, Genu valgum, Flat distal femoral epiphysis, Short femoral neck, Coxa vara, Ep...	OMIM:609324
Acheiropody	Short tibia, Aplasia of the phalanges of the hand, Absent toe, Aplasia of metacarpal bones, Aplas...	OMIM:200500
Tibial Aplasia-Ectrodactyly Syndrome	Aplasia/Hypoplasia of the tibia, Preaxial hand polydactyly, Finger syndactyly, Patellar aplasia, ...	ORPHA:3329
Chondrodysplasia, Lethal, With Long Bone Angulation And Mixed Bone Density	Short tibia, Hypoplasia of the radius, Lytic defects of humeral diaphysis, Short femur, Hypoplasi...	OMIM:601376
Blount Disease	Abnormal tibial metaphysis morphology, Abnormality of the knee, Abnormality of the proximal tibia...	ORPHA:2768
Lethal Faciocardiomelic Dysplasia	Short tibia, Radial club hand, Short 5th finger, Hypoplasia of the radius, Microretrognathia, Hyp...	ORPHA:1972
Epiphyseal Dysplasia, Multiple, 5	Broad femoral neck, Metaphyseal irregularity, Genu valgum, Coxa vara, Short metacarpal, Short fem...	OMIM:607078
Leri-Weill Dyschondrosteosis	Short tibia, Short toe, Short 4th metacarpal, Coxa valga, Abnormal carpal morphology, Hypoplasia ...	OMIM:127300
Léri-Weill Dyschondrosteosis	Short tibia, Abnormal carpal morphology, Abnormal metaphysis morphology, Genu valgum, Abnormality...	ORPHA:240
Epiphyseal Dysplasia, Multiple, 7	Genu varum, Advanced ossification of carpal bones, Short femoral neck, Flat acetabular roof, Epip...	OMIM:617719
Skeletal Defects, Genital Hypoplasia, And Impaired Intellectual Development	Short tibia, Absent thumb, Short femur, Hypoplasia of the ulna, Aplasia/Hypoplasia of the radius,...	OMIM:612447
Spondylometaphyseal Dysplasia, Corner Fracture Type	Genu varum, Metaphyseal irregularity, Short femoral neck, Coxa vara, Corner fracture of metaphysi...	OMIM:184255
Dyschondrosteosis And Nephritis	Short tibia, Radial bowing, Ulnar bowing, Short forearm	OMIM:127350
Spondyloepimetaphyseal Dysplasia, Missouri Type	Genu varum, Metaphyseal irregularity, Short lower limbs, Femoral bowing, Flared metaphysis, Flatt...	ORPHA:93356
Fibular Hemimelia	Short tibia, Hip subluxation, Limited knee flexion/extension, Hypoplastic acetabulae, Toe syndact...	ORPHA:93323
Laurin-Sandrow Syndrome	Triphalangeal thumb, Broad foot, Patellar aplasia, Absent tibia, Hand polydactyly, Syndactyly, Ab...	OMIM:135750
Endove Syndrome, Limb-Only Type	Aplasia of the distal phalanges of the toes, Disproportionate shortening of the tibia, Cutaneous ...	OMIM:619217
Epiphyseal Dysplasia, Multiple, With Miniepiphyses	Genu varum, Broad femoral neck, Patellar hypoplasia, Short femoral neck, Epiphyseal dysplasia, Ir...	OMIM:609325
Epiphyseal Dysplasia, Multiple, 4	Short metacarpal, Double-layered patella, Hip dysplasia, Flat capital femoral epiphysis, Epiphyse...	OMIM:226900
Tibial Hemimelia-Polysyndactyly-Triphalangeal Thumb Syndrome	Aplasia/Hypoplasia of the tibia, Aplasia/Hypoplasia of the thumb, Patellar aplasia, Synostosis of...	ORPHA:988
Femur, Unilateral Bifid, With Monodactylous Ectrodactyly	Hand monodactyly, Absent tibia, Bifid femur, Aplasia of the ulna, Split hand, Foot monodactyly	OMIM:228250
Autosomal Dominant Myopia-Midfacial Retrusion-Sensorineural Hearing Loss-Rhizomelic Dysplasia Syndrome	Dumbbell-shaped long bone, Rhizomelia, Micrognathia, Micromelia, Short femur, Femoral bowing, Bra...	ORPHA:440354
Legg-Calvé-Perthes Disease	Cartilage destruction	ORPHA:2380
Acrofacial Dysostosis Syndrome Of Rodriguez	Short tibia, Triphalangeal thumb, 11 pairs of ribs, Wide anterior fontanel, Micrognathia, Clinoda...	OMIM:201170
Orofaciodigital Syndrome Viii	Short tibia, Polydactyly, Syndactyly	OMIM:300484
Spondyloepimetaphyseal Dysplasia With Hypotrichosis	Genu varum, Short femoral neck, Coxa vara, Rhizomelia, Flared iliac wing, Proximal femoral metaph...	OMIM:183849
Mesomelic Dysplasia, Savarirayan Type	Metatarsus valgus, Broad tibial metaphyses, Flared radial metaphysis, Hip dislocation, Narrow ili...	ORPHA:85170
Chromosome 17P13.3, Telomeric, Duplication Syndrome	Short tibia, Short toe, Short phalanx of finger, Absent toe, Short metacarpal, Absent tibia, Camp...	OMIM:612576
Acheiropodia	Aplasia of the ulna, Upper limb phocomelia, Absent radius, Abnormal metaphysis morphology, Abnorm...	ORPHA:931
Orofaciodigital Syndrome Type 10	Short tibia, Short toe, Mesomelic leg shortening, Micrognathia, Metatarsal synostosis, Oligodacty...	ORPHA:2756
Osteofibrous Dysplasia, Susceptibility To	Pseudoarthrosis, Fibular hypoplasia	OMIM:607278
Langer Mesomelic Dysplasia	Aplasia/Hypoplasia of the fibula, Mesomelic/rhizomelic limb shortening, Short femoral neck, Abnor...	ORPHA:2632
Fibular Aplasia Or Hypoplasia, Femoral Bowing And Poly-, Syn-, And Oligodactyly	Toe syndactyly, Aplasia/hypoplasia of the femur, Postaxial hand polydactyly, Talipes equinovarus,...	OMIM:228930
Tibial Hemimelia	Absent tibia	OMIM:275220
Split-Hand/Foot Malformation With Long Bone Deficiency 1	Patellar aplasia, Hand monodactyly, Absent tibia, Short hallux, Split foot, Split hand, Aplasia o...	OMIM:119100
Metaphyseal Chondrodysplasia, Schmid Type	Genu varum, Metaphyseal irregularity, Genu valgum, Metaphyseal sclerosis, Proximal femoral metaph...	OMIM:156500
Tibial Hemimelia	Short tibia, Polydactyly, Coxa valga, Hip dislocation, Metatarsus adductus, Aplasia of the 2nd me...	ORPHA:93322
Femoral-Facial Syndrome	Aplasia/Hypoplasia of the tibia, Coxa vara, Hip dysplasia, Preaxial foot polydactyly, Micrognathi...	ORPHA:1988
Acromesomelic Dysplasia 2B	Short phalanx of finger, Deviation of finger, Malaligned carpal bone, Short metacarpal, Patellar ...	OMIM:228900
Eiken Syndrome	Short phalanx of finger, Short toe, Metaphyseal irregularity, Broad foot, Abnormal fingertip morp...	ORPHA:79106
Brachydactyly-Ectrodactyly With Fibular Aplasia Or Hypoplasia	Short phalanx of finger, Aplasia/Hypoplasia of the fibula, Split foot, Brachydactyly, Fibular apl...	OMIM:113310
Epiphyseal Dysplasia, Multiple, 1	Short phalanx of finger, Broad femoral neck, Genu valgum, Short femoral neck, Avascular necrosis ...	OMIM:132400
Multiple Epiphyseal Dysplasia, Lowry Type	Knee flexion contracture, Genu valgum, Rhizomelia, Micrognathia, Fragmented epiphyses, Epiphyseal...	ORPHA:166016
Metaphyseal Chondrodysplasia, Schmid Type	Short tubular bones of the hand, Limb undergrowth, Metaphyseal cupping of proximal phalanges, Met...	ORPHA:174
Fibular Dimelia-Diplopodia Syndrome	Absent tibia	ORPHA:1757
Atelosteogenesis, Type I	Vertebral hypoplasia, Micrognathia, Distal tapering femur, Short femur, Limb undergrowth, Knee di...	OMIM:108720
Weismann-Netter Syndrome	Abnormality of the humerus, Tibial bowing, Femoral bowing, Abnormal morphology of ulna, Abnormali...	ORPHA:3344
Epiphyseal Dysplasia, Baumann Type	Metaphyseal irregularity, Genu valgum, Aplasia of metacarpal bones, Narrow pelvis bone, Clinodact...	OMIM:610797
Spondyloepimetaphyseal Dysplasia With Abnormal Dentition	Broad femoral neck, Genu valgum, Pseudoepiphyses, Tapered finger, Metaphyseal irregularity, Short...	OMIM:601668
Atelosteogenesis Type Ii	Short phalanx of finger, Micrognathia, Camptodactyly, Short femur, Metatarsus adductus, Increased...	ORPHA:56304
Pelviscapular Dysplasia	Mesomelic leg shortening, Hypoplastic ilia, Humeroradial synostosis, Short femur, Congenital hip ...	ORPHA:93333
Pseudoachondroplasia	Short phalanx of finger, Irregular carpal bones, Limb undergrowth, Irregular acetabular roof, Del...	ORPHA:750
Thanatophoric Dysplasia Type 1	Wide anterior fontanel, Hypoplastic ilia, Micromelia, Short femur, Femoral bowing, Abnormal sacro...	ORPHA:1860
Orofaciodigital Syndrome Iv	Short tibia, Toe syndactyly, Foot polydactyly, Micrognathia, Short finger, Hand polydactyly, Clin...	OMIM:258860
Brachial Amelia, Cleft Lip, And Holoprosencephaly	Amelia, Foot oligodactyly, Short femur	OMIM:601357
Metaphyseal Dysplasia, Braun-Tinschert Type	Broad tibial metaphyses, Broad femoral head, Fibular bowing, Exostoses of the radius, Hypoplasia ...	ORPHA:85188
Kyphomelic Dysplasia	Short metacarpal, Radial bowing, Micrognathia, Flat acetabular roof, Ulnar bowing, Short femur, F...	OMIM:211350
Ivic Syndrome	Triphalangeal thumb, Absent thumb, Upper limb undergrowth, Short 1st metacarpal, Hypoplasia of th...	OMIM:147750
Grant Syndrome	Micrognathia, Down-sloping shoulders, Tibial bowing	OMIM:138930
Fibular Aplasia-Complex Brachydactyly Syndrome	Aplasia/Hypoplasia of the fibula, Synostosis of carpal bones, Abnormal morphology of the radius, ...	ORPHA:2639
Osteosclerosis With Ichthyosis And Fractures	Tibial bowing, Cortical thickening of long bone diaphyses, Femoral bowing	OMIM:166740
Mesomelic Dwarfism, Reinhardt-Pfeiffer Type	Synostosis of carpal bones, Ulnar deviation of finger, Hypoplasia of the ulna, Abnormal morpholog...	ORPHA:2634
Congenital Disorder Of Glycosylation, Type Ig	Short tibia, Rhizomelia, Short ribs, Hypoplasia of the radius, Short femur, Sandal gap, Short hum...	OMIM:607143
Paget Disease Of Bone 2, Early-Onset	Femoral bowing, Short femur, Osteosclerosis of the ulna, Bowing of the long bones, Fractures of t...	OMIM:602080
Spondyloepimetaphyseal Dysplasia, Missouri Type	Genu varum, Metaphyseal cupping, Coxa vara, Rhizomelia, Radial bowing, Flared iliac wing, Ulnar b...	OMIM:602111
Achondroplasia	Genu varum, Short femoral neck, Rhizomelia, Short ribs, Radial bowing, Ulnar bowing, Short femur,...	OMIM:100800
Robin Sequence With Cleft Mandible And Limb Anomalies	Short tibia, Short phalanx of finger, Hip subluxation, Short 5th finger, Micrognathia, Hip disloc...	OMIM:268305
Short Rib-Polydactyly Syndrome	Short tibia, Polydactyly, Abnormal pelvis bone ossification, Limb undergrowth, Short ribs, Acetab...	ORPHA:1505
Vitamin D-Dependent Rickets, Type 2B, With Normal Vitamin D Receptor	Genu varum, Metaphyseal irregularity, Genu valgum, Bulging epiphyses, Rickets of the lower limbs,...	OMIM:600785
Spondyloepiphyseal Dysplasia Congenita	Genu valgum, Upper limb undergrowth, Short femoral neck, Short long bone, Abnormal foot morpholog...	ORPHA:94068
Atelosteogenesis Type I	Abnormal ossification involving the femoral head and neck, Rhizomelia, Short long bone, Micrognat...	ORPHA:1190
Fatco Syndrome	Finger syndactyly, Tarsal synostosis, Abnormality of tibia morphology, Split hand, Abnormality of...	ORPHA:2492
Orofaciodigital Syndrome Ix	Short tibia, Hand polydactyly, Camptodactyly, Toe syndactyly	OMIM:258865
Atelosteogenesis Type Iii	Short tibia, Short tubular bones of the hand, Patellar dislocation, Vertebral hypoplasia, Abnorma...	ORPHA:56305
Weismann-Netter Syndrome	Lateral femoral bowing, Squared iliac bones, Anterior tibial bowing, Fibular bowing	OMIM:112350
Laurin-Sandrow Syndrome	Triphalangeal thumb, Aplasia/Hypoplasia of the thumb, Preaxial hand polydactyly, Limb duplication...	ORPHA:2378
Faciocardiomelic Dysplasia, Lethal	Short 5th finger, Hypoplasia of the radius, Micrognathia, Hypoplasia of the ulna, Talipes, Short ...	OMIM:227270
Microcephaly-Micromelia Syndrome	Short tibia, Absent thumb, Humeroradial synostosis, Micrognathia, Missing ribs, Micromelia, Oligo...	OMIM:251230
Metaphyseal Dysostosis-Intellectual Disability-Conductive Deafness Syndrome	Metaphyseal dysplasia, Genu varum, Broad foot, Short foot, Broad tibial metaphyses, Short femoral...	ORPHA:2502
Osteochondrodysplasia, Complex Lethal, Symoens-Barnes-Gistelinck Type	Fractured radius, Short ribs, Micrognathia, Short femur, Adducted thumb, Flared metaphysis, Limb ...	OMIM:616897
Slc35A2-Cdg	Short tibia, Camptodactyly of finger, Hip subluxation, Coxa valga, Abnormal long bone morphology,...	ORPHA:356961
Thalidomide Embryopathy	Triphalangeal thumb, Aplasia/Hypoplasia of the thumb, Radial club hand, Preaxial hand polydactyly...	ORPHA:3312
Microphthalmia With Limb Anomalies	Short tibia, Toe syndactyly, Micrognathia, Hip dislocation, Postaxial hand polydactyly, Talipes e...	ORPHA:1106
Stuve-Wiedemann Syndrome 1	Short tibia, Short phalanx of finger, Metaphyseal rarefaction, Micrognathia, Camptodactyly, Hypop...	OMIM:601559
Metaphyseal Acroscyphodysplasia	Short phalanx of finger, Short toe, Genu varum, Metaphyseal cupping, Coxa valga, Short metacarpal...	OMIM:250215
Acromesomelic Dysplasia 3	Aplasia of the proximal phalanx of the 2nd finger, Short phalanx of finger, Short toe, Broad foot...	OMIM:609441
Clubfoot, Congenital, With Or Without Deficiency Of Long Bones And/Or Mirror-Image Polydactyly	Patellar hypoplasia, Preaxial foot polydactyly, Absent tibia, Mirror image foot polydactyly, Bila...	OMIM:119800
Spondylometaphyseal Dysplasia With Cone-Rod Dystrophy	Metaphyseal irregularity, Metaphyseal cupping, Coxa vara, Short metacarpal, Rhizomelia, Hypoplast...	OMIM:608940
Ollier Disease	Abnormal metaphysis morphology, Multiple enchondromatosis, Abnormal cartilage morphology, Micromelia	ORPHA:296
Craniosynostosis With Fibular Aplasia	Fibular aplasia	OMIM:218550
Bent Bone Dysplasia Syndrome 2	Short tibia, Hypoplastic iliac wing, Short sternum, Hypoplastic acetabulae, Short 1st metacarpal,...	OMIM:620076
Spondyloepimetaphyseal Dysplasia, Borochowitz-Cormier-Daire Type	Dysplastic iliac wing, Metaphyseal spurs, Hypoplastic pubic bone, Short long bone, Flat acetabula...	OMIM:608728
Shox-Related Short Stature	Genu valgum, Micrognathia, Lower limb undergrowth, Ulnar radial head dislocation, Forearm undergr...	ORPHA:314795
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly	Cone-shaped epiphysis, Short long bone, Short ribs, Absent tibia, Short digit, Talipes equinovaru...	OMIM:613091
Ophthalmomandibulomelic Dysplasia	Coxa valga, Radial bowing, Lateral humeral condyle aplasia, Mesomelia, Fibular hypoplasia	OMIM:164900
Orofaciodigital Syndrome Vi	11 pairs of ribs, Preaxial hand polydactyly, Toe syndactyly, Preaxial foot polydactyly, Central Y...	OMIM:277170
Multiple Epiphyseal Dysplasia Type 4	Skewfoot, Broad foot, Micrognathia, Metatarsal synostosis, Abnormal forearm bone morphology, Flat...	ORPHA:93307
Brachyphalangy, Polydactyly, And Tibial Aplasia/Hypoplasia	Short phalanx of finger, Aplasia/hypoplasia of the femur, Toe syndactyly, Flared iliac wing, Micr...	OMIM:609945
Osteogenesis Imperfecta, Type X	Genu valgum, Rhizomelia, Micrognathia, Micromelia, Short femur, Fibular bowing, Bowing of the lon...	OMIM:613848
Orofaciodigital Syndrome X	Hand oligodactyly, Coalescence of tarsal bones, Preaxial hand polydactyly, Fibular aplasia	OMIM:165590
Phocomelia-Ectrodactyly, Ear Malformation, Deafness, And Sinus Arrhythmia	Shoulder dislocation, Aplasia/Hypoplasia of the thumb, Genu varum, Asymmetric radial dysplasia, R...	OMIM:171480
Short-Rib Thoracic Dysplasia 13 With Or Without Polydactyly	Short tibia, Rhizomelia, Short long bone, Short ribs, Flat acetabular roof, Microretrognathia, Hy...	OMIM:616300
Lethal Kniest-Like Dysplasia	Abnormality of the ischium, Wide anterior fontanel, Hypoplastic ilia, Short ribs, Mesomelic/rhizo...	ORPHA:2347
Caffey Disease	Bowing of the legs, Periosteal thickening of long tubular bones, Tibial bowing	OMIM:114000
Thrombocytopenia-Absent Radius Syndrome	Genu varum, Coxa valga, Finger syndactyly, Patellar dislocation, Tibial torsion, Micrognathia, Hi...	ORPHA:3320
Kniest Dysplasia	Genu varum, Dumbbell-shaped long bone, Splayed epiphyses, Coxa vara, Hip contracture, Rhizomelia,...	OMIM:156550
Short-Rib Thoracic Dysplasia 20 With Polydactyly	Short tibia, Hypoplastic pubic bone, Wide anterior fontanel, Short long bone, Short ribs, Microgn...	OMIM:617925
Hyperparathyroidism, Transient Neonatal	Short long bone, Short ribs, Femoral bowing, Short femur, Fractured rib, Metaphyseal spurs	OMIM:618188
Boomerang Dysplasia	Hypoplastic iliac body, Fibular aplasia, Absent radius	OMIM:112310
Omodysplasia 1	Short tibia, Limited knee flexion/extension, Anterolateral radial head dislocation, Rhizomelia, M...	OMIM:258315
Eiken Syndrome	Broad femoral neck, Pseudoepiphyses, Long hallux, Narrow pelvis bone, Flat acetabular roof, Clino...	OMIM:600002
Acrofacial Dysostosis, Rodríguez Type	Finger syndactyly, Radioulnar synostosis, Microretrognathia, Abnormal pelvic girdle bone morpholo...	ORPHA:1788
Saul-Wilson Syndrome	Coxa valga, Wide anterior fontanel, Short metacarpal, Enlarged epiphyses, Micrognathia, Hypoplasi...	OMIM:618150
Microphthalmia With Limb Anomalies	Foot oligodactyly, Capitate-hamate fusion, 2-5 toe syndactyly, Toe syndactyly, Hip dislocation, M...	OMIM:206920
Dyggve-Melchior-Clausen Disease	Broad foot, Camptodactyly, Flat glenoid fossa, Narrow greater sciatic notch, Talipes equinovarus,...	OMIM:223800
Hypophosphatemic Rickets, X-Linked Dominant	Shortening of the talar neck, Trapezoidal distal femoral condyles, Metaphyseal irregularity, Genu...	OMIM:307800
Severe Achondroplasia-Developmental Delay-Acanthosis Nigricans Syndrome	Aplasia/Hypoplasia of the mandible, Femoral bowing, Metaphyseal chondrodysplasia, Fibular bowing,...	ORPHA:85165
Multiple Osteochondromas	Coxa valga, Abnormal carpal morphology, Limb undergrowth, Genu valgum, Abnormality of the knee, F...	ORPHA:321
Short-Rib Thoracic Dysplasia 6 With Or Without Polydactyly	Disproportionate shortening of the tibia, Preaxial hand polydactyly, Short long bone, Short ribs,...	OMIM:263520
Acromelic Frontonasal Dysostosis	Short tibia, Polydactyly, Patellar hypoplasia, Preaxial foot polydactyly, Syndactyly, Preaxial po...	OMIM:603671
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome	Radial bowing, Micrognathia, Lower limb undergrowth, Abnormality of the lower limb, Abnormality o...	ORPHA:3035
Orofaciodigital Syndrome Type 2	Short tibia, Broad first metatarsal, Mesomelic leg shortening, Finger syndactyly, Preaxial foot p...	ORPHA:2751
Kagami-Ogata Syndrome Due To Paternal Uniparental Disomy Of Chromosome 14	Short tibia, Coxa valga, Micrognathia, Epiphyseal stippling, Camptodactyly, Metatarsus adductus, ...	ORPHA:96334
Intellectual Developmental Disorder, Autosomal Dominant 53	Genu valgum, Short femur	OMIM:617798
Catel-Manzke Syndrome	Short toe, Genu valgum, Short metacarpal, Micrognathia, Camptodactyly, Clinodactyly of the 5th fi...	OMIM:616145
Pelvis-Shoulder Dysplasia	Camptodactyly of finger, Aplasia/Hypoplasia of the fibula, Hypoplastic pubic bone, Mesomelic/rhiz...	ORPHA:2839
Fibrochondrogenesis 1	Dumbbell-shaped long bone, Wide anterior fontanel, Short foot, Short long bone, Small hand, Short...	OMIM:228520
Czech Dysplasia	Short toe, Short femoral neck, Coxa vara, Short metacarpal, Flat capital femoral epiphysis, Narro...	OMIM:609162
Spondyloepiphyseal Dysplasia Tarda	Finger swelling, Coxa vara, Short femoral neck, Flattened femoral head, Enlarged epiphyses of the...	ORPHA:93284
Microcephalic Osteodysplastic Primordial Dwarfism, Type I	Micrognathia, Hip dislocation, Short femur, Limb undergrowth, Bifid first metacarpal, Delayed epi...	OMIM:210710
Larsen-Like Syndrome, Lethal Type	Abnormal cartilage matrix	OMIM:245650
Acro-Renal-Mandibular Syndrome	Finger syndactyly, Hypoplasia of the radius, Micrognathia, Hip dislocation, Hypoplasia of the uln...	ORPHA:958
Midface Hypoplasia, Hearing Impairment, Elliptocytosis, And Nephrocalcinosis	Micrognathia, Clinodactyly of the 5th finger, Pes planus, Short femur, Talipes, Talipes equinovar...	OMIM:300990
Omodysplasia 2	Rhizomelic arm shortening, Broad femoral neck, Short 1st metacarpal, Micrognathia, Clinodactyly o...	OMIM:164745
Lissencephaly Type 3-Metacarpal Bone Dysplasia Syndrome	Short metacarpal, Abnormal cartilage matrix, Epiphyseal stippling, Short distal phalanx of finger...	ORPHA:86822
8Q24.3 Microdeletion Syndrome	Short 5th finger, Short middle phalanx of the 5th finger, Hip dysplasia, Clinodactyly of the 5th ...	ORPHA:508488
Occipital Horn Syndrome	Genu valgum, Humerus varus, Coxa valga, Avascular necrosis of the capital femoral epiphysis, Apla...	ORPHA:198
Phocomelia, Schinzel Type	Foot oligodactyly, Humeroradial synostosis, Hypoplasia of the radius, Radial bowing, Micrognathia...	ORPHA:2879
Schneckenbecken Dysplasia	Dumbbell-shaped long bone, Hypoplastic ilia, Short ribs, Diaphyseal thickening, Micromelia, Hypop...	ORPHA:3144
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria	Polydactyly, Short humerus, Short femur	ORPHA:17
Campomelic Dysplasia	11 pairs of ribs, Short long bone, Hypoplastic inferior ilia, Micrognathia, Hip dislocation, Femo...	ORPHA:140
Seckel Syndrome 1	11 pairs of ribs, Micrognathia, Ivory epiphyses, Hip dislocation, Abnormal finger flexion crease,...	OMIM:210600
Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly	Short phalanx of finger, Hypoplastic iliac wing, Metaphyseal irregularity, Short ribs, Foot polyd...	OMIM:208500
Ulna And Fibula, Absence Of, With Severe Limb Deficiency	Humeroradial synostosis, Aplasia/hypoplasia of the femur, Hip dislocation, Phocomelia, Aplasia/Hy...	OMIM:276820
Mesomelia-Synostoses Syndrome	Short phalanx of finger, Progressive forearm bowing, Tarsometatarsal synostosis, Carpometacarpal ...	OMIM:600383
Acrorenal-Mandibular Syndrome	Toe syndactyly, Foot polydactyly, Hypoplasia of the radius, Micrognathia, Hand polydactyly, Hip d...	OMIM:200980
Cousin Syndrome	Hypoplastic iliac wing, 2-3 toe syndactyly, Hypoplastic pubic bone, Rhizomelia, Humeroradial syno...	OMIM:260660
Thrombocytopenia-Absent Radius Syndrome	Short phalanx of finger, Absent thumb, Coxa valga, Patellar dislocation, Micrognathia, Hip disloc...	OMIM:274000
Acromelic Frontonasal Dysplasia	Preaxial foot polydactyly, Patellar hypoplasia, Aplasia/Hypoplasia of the tibia, Talipes equinovarus	ORPHA:1827
Wiedemann-Rautenstrauch Syndrome	Genu varum, Hypoplastic ilia, Slender long bone, Micrognathia, Clinodactyly, Short femur, Long fo...	OMIM:264090
Campomelic Dysplasia	Short phalanx of finger, Hallux valgus, Micrognathia, Hip dislocation, Metatarsus adductus, Dislo...	OMIM:114290
Hydrolethalus Syndrome 1	Upper limb undergrowth, Preaxial hand polydactyly, Micrognathia, Proximal tibial hypoplasia, Dupl...	OMIM:236680
Wiedemann-Rautenstrauch Syndrome	Camptodactyly of finger, 2-3 toe syndactyly, Hypoplastic ilia, Hip dysplasia, Short femur, Hypopl...	ORPHA:3455
Otopalatodigital Syndrome, Type Ii	Toe syndactyly, Micrognathia, Broad hallux, Short hallux, Postaxial hand polydactyly, Rocker bott...	OMIM:304120
Femoral-Facial Syndrome	Hypoplastic acetabulae, Preaxial hand polydactyly, Humeroradial synostosis, Toe syndactyly, Aplas...	OMIM:134780
Familial Osteodysplasia, Anderson Type	Aplastic clavicle, Aplasia/hypoplasia of the femur, Missing ribs, Clinodactyly of the 5th finger,...	ORPHA:2769
Orofaciodigital Syndrome Type 4	Camptodactyly of finger, Genu varum, Aplasia/Hypoplasia of the tibia, Preaxial hand polydactyly, ...	ORPHA:2753
Cranioectodermal Dysplasia 1	Short toe, Rhizomelia, Short ribs, Clinodactyly, Short humerus, Radial deviation of finger, Flatt...	OMIM:218330
Osteopathia Striata With Cranial Sclerosis	Paranasal sinus hypoplasia, Flexion contracture of toe, Micrognathia, Talipes equinovarus, Campto...	OMIM:300373
Microcephalic Osteodysplastic Primordial Dwarfism Types I And Iii	Aplastic clavicle, Abnormal finger morphology, Large iliac wing, Aplasia/hypoplasia of the femur,...	ORPHA:2636
Kinsship Syndrome	Polydactyly, Coxa valga, Micrognathia, Hip dislocation, Dislocated radial head, Mesomelia, Fibula...	OMIM:619297
Charge Syndrome	Hand monodactyly, Micrognathia, Absent tibia, Hand polydactyly, Bifid femur, Down-sloping shoulde...	OMIM:214800
Ulbright-Hodes Syndrome	Short sternum, Humeroradial synostosis, Short metacarpal, Hypoplasia of the radius, Micrognathia,...	ORPHA:3404
Encephalocraniocutaneous Lipomatosis	Abnormal cartilage morphology	ORPHA:2396

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Itga10

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Itga10.

No publications found that use IMPC mice or data for Itga10.

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MGI Allele	Allele Type	Produced
Itga10^{tm1(KOMP)Vlcg}	Reporter-tagged deletion allele (with selection cassette)	ES Cells
Itga10^{tm1a(EUCOMM)Hmgu}	KO first allele (reporter-tagged insertion with conditional potential)	Targeting vectors, ES Cells
Itga10^{tm1e(EUCOMM)Hmgu}	Targeted, non-conditional allele	ES Cells

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