Gene: Cnnm2

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Phenotype System Allele Zyg Sex Life Stage P Value
enlarged heart Cnnm2tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal craniofacial morphology Cnnm2tm1.1(KOMP)Vlcg HOM E15.5 0.00
abnormal head shape Cnnm2tm1.1(KOMP)Vlcg HOM E15.5 0.00
embryonic growth retardation Cnnm2tm1.1(KOMP)Vlcg HOM E15.5 0.00
preweaning lethality, complete penetrance Cnnm2tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal heart morphology Cnnm2tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal head size Cnnm2tm1.1(KOMP)Vlcg HOM E15.5 0.00
decreased startle reflex Cnnm2tm1.1(KOMP)Vlcg HET Early adult 5.17×10-06

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (1/2)  Section images
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 4  (1/57) N/A
Axial skeleton 4  (1/61) N/A
Brain 4  (6/504) N/A
Central nervous system ganglion 4  (1/70) N/A
Dorsal root ganglion 3  (1/57) N/A
Ear 4  (1/504) N/A
Embryo 4  (1/505) N/A
Outer ear 4  (1/66) N/A
Eye 4  (1/504) N/A
Foot 4  (1/504) N/A
Forebrain 4  (1/504) N/A
Forelimb 4  (1/504) N/A
Fronto-nasal process 4  (1/58) N/A
Hand 3  (1/503) N/A
Head 4  (5/504) N/A
Head mesenchyme 4  (1/57) N/A
Heart 4  (1/504) N/A
Heart ventricle 4  (1/57) N/A
Hindbrain 4  (6/504) N/A
Hindlimb 4  (1/503) N/A
Intestine 1  (1/55) N/A
Liver 4  (1/504) N/A
Mandibular process 4  (1/504) N/A
Maxillary process 4  (1/504) N/A
Meckel's cartilage 3 N/A
Midbrain 4  (1/504) N/A
Nasal septum 4  (1/57) N/A
Nose 4  (1/70) N/A
Notochord 4  (1/57) N/A
Oral cavity 4  (1/504) N/A
Outflow tract 4  (1/57) N/A
Pharynx 1  (1/52) N/A
4  (7/37) N/A
Skeleton 4  (1/70) N/A
Skin 4  (1/504) N/A
Spinal cord 4  (1/69) N/A
Tail 4  (1/504) N/A
Tail somite 4  (1/504) N/A
Trunk mesenchyme 4  (1/57) N/A
Umbilical artery embryonic part 4  (1/57) N/A
Umbilical vein embryonic part 4  (1/57) N/A
Vibrissa 4  (1/66) N/A

 Associated Images

Adult LacZ: LacZ Images Section
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cnnm2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Cnnm2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Cnnm2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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