Gene: Usp53

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Name
ubiquitin specific peptidase 53
MGI ID
MGI:2139607
Synonyms
Sp6 Phxr3 mbo
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased prepulse inhibition Usp53em1(IMPC)Tcp HOM Early adult 2.35×10-28
abnormal startle reflex Usp53em1(IMPC)Tcp HOM Early adult 1.37×10-17
increased circulating serum albumin level Usp53em1(IMPC)Tcp HOM Early adult 4.63×10-06
decreased bone mineral content Usp53em1(IMPC)Tcp HOM Early adult 6.71×10-14
increased or absent threshold for auditory brainstem response Usp53em1(IMPC)Tcp HOM Early adult 0.00
decreased bone mineral density Usp53em1(IMPC)Tcp HOM Early adult 4.27×10-13
abnormal coat/ hair morphology Usp53em1(IMPC)Tcp HOM Early adult 3.05×10-08
increased circulating alkaline phosphatase level Usp53em1(IMPC)Tcp HOM Early adult 8.35×10-13
decreased startle reflex Usp53em1(IMPC)Tcp HOM Early adult 5.72×10-27

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Usp53em1(IMPC)Tcp Exon Deletion Mice
Usp53tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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