Tmem108 | transmembrane protein 108
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton
12 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased bone mineral content | 1 supporting dataset | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 8.85x10-5 | ||
increased total body fat amount | 2 supporting datasets | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.06x10-5 | ||
decreased lean body mass | 1 supporting dataset | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.69x10-6 | ||
abnormal cornea morphology | 1 supporting dataset | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.29x10-5 | ||
abnormal auditory brainstem response | 2 supporting datasets | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.7x10-5 | ||
limb grasping | 1 supporting dataset | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.95x10-5 | ||
increased circulating aspartate transaminase level | 1 supporting dataset | Tmem108tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.96x10-9 |
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External links
No external links available for Tmem108.
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Tmem108tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Tmem108tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |