Asb2 | ankyrin repeat and SOCS box-containing 2
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Immune system Adipose tissue Embryo Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Mortality/aging
11 No significant impact
5 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
64Embryo tissues
abnormal embryo size | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
decreased total body fat amount | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | heterozygote | Early adult | 6.11x10-5 | ||
abnormal vitelline vasculature morphology | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
increased Ly6C-positive immature NK cell number | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | heterozygote | Early adult | 0 | ||
abnormal retina blood vessel morphology | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | heterozygote | Early adult | 1.13x10-5 | ||
embryonic growth retardation | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
pale yolk sac | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
increased lean body mass | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | heterozygote | Early adult | 9.87x10-5 | ||
decreased Ly6C-positive immature NK cell number | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | heterozygote | Early adult | 7x10-12 | ||
abnormal pericardium morphology | 1 supporting dataset | Asb2tm2b(KOMP)Wtsi | homozygote | E9.5 | N/A * |
| | | | | | | | | |
External links
No external links available for Asb2.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Asb2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Asb2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
Asb2tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Asb2tm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Asb2tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
Asb2tm41925(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |