Gene Summary

Name:
von Willebrand factor C and EGF domains
Synonyms:
1300015B04Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
increased bone mineral content Vwceem1(IMPC)Bay HOM Early adult 4.55×10-06
preweaning lethality, incomplete penetrance Vwceem1(IMPC)Bay HOM Early adult 0.00
abnormal bone structure Vwceem1(IMPC)Bay HOM Early adult 1.85×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Vwce mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Vwce by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Melorheostosis, Isolated
Hyperostosis, Increased bone mineral density OMIM:155950

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Vwce

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Vwce.

No publications found that use IMPC mice or data for Vwce.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Vwceem1(IMPC)Bay Exon Deletion Mice
Vwcetm185080(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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