Gene: Asf1a

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Name
anti-silencing function 1A histone chaperone
MGI ID
MGI:1913653
Synonyms
2310079C17Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Asf1atm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic growth retardation Asf1atm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal embryo size Asf1atm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal neural tube morphology Asf1atm1b(KOMP)Wtsi HET E9.5 0.00
abnormal embryo size Asf1atm1b(KOMP)Wtsi HET E9.5 0.00
abnormal neural tube morphology Asf1atm1b(KOMP)Wtsi HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Asf1atm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal embryo turning Asf1atm1b(KOMP)Wtsi HET E9.5 0.00
abnormal neural tube closure Asf1atm1b(KOMP)Wtsi HET E9.5 0.00
abnormal neural tube closure Asf1atm1b(KOMP)Wtsi HOM E9.5 0.00
embryonic growth retardation Asf1atm1b(KOMP)Wtsi HET E9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) N/A
Dorsal root ganglion 1  (1/57) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505) N/A
Eye 2  (1/504) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504) N/A
Fronto-nasal process 1  (1/58) N/A
Hand 2  (1/503) N/A
Head 2  (5/504) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Nose 1  (1/70) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Spinal cord 1  (1/69) N/A
Tail 2  (1/504) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Combined SHIRPA and Dysmorphology
2 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
Sleep Wake: Wake state (bmp file)
13 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Asf1atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Asf1atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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