Gene: Cdh23

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Name
cadherin 23 (otocadherin)
MGI ID
MGI:1890219
Synonyms
nmf112 USH1D 4930542A03Rik ahl nmf181 nmf252 mdfw bob sals
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N/A
Other links
Expression & images (0) Disease models (0) Order (7)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating sodium level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.72×10-08
decreased circulating calcium level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.77×10-05
increased T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 8.00×10-07
decreased leukocyte cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 9.56×10-09
increased CD4-positive, alpha beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.49×10-05
impaired righting response Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 7.66×10-14
increased bone mineral content Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.04×10-07
increased alpha-beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 6.00×10-07
preweaning lethality, incomplete penetrance Cdh23tm2b(EUCOMM)Wtsi HOM n/a 0.00
decreased lean body mass Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.77×10-05
increased CD8-positive, alpha-beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
decreased body length Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.33×10-05
decreased fasted circulating glucose level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.64×10-15
increased NK cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
increased mean corpuscular volume Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 9.17×10-12
decreased Ly6C high monocyte number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 7.00×10-07
decreased mature B cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
decreased bone mineral content Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.23×10-05
decreased circulating triglyceride level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 5.46×10-05
abnormal gait Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.07×10-14
abnormal bone structure Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.73×10-09
decreased circulating insulin level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.64×10-06
decreased circulating glucose level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.33×10-07
decreased monocyte cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.49×10-05
decreased total body fat amount Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.77×10-11
decreased eosinophil cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
absent pinna reflex Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.56×10-18
trunk curl Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 3.60×10-19
increased lean body mass Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.71×10-09
decreased Ly6C low monocyte number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 6.00×10-07
increased circulating chloride level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.84×10-18
decreased B cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.39×10-05
stereotypic behavior Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 3.80×10-20
increased mean corpuscular hemoglobin Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.13×10-05
decreased circulating LDL cholesterol level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.08×10-05

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 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cdh23em2H Point Mutation Mice
Cdh23em1H Point Mutation Mice
Cdh23tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cdh23tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cdh23em3(IMPC)H Point Mutation Mice
Cdh23tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cdh23tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells