Genes Phenotypes

Gene: Cdh23

Log in to follow

Name
cadherin 23 (otocadherin)
MGI ID
MGI:1890219
Synonyms
nmf112 USH1D 4930542A03Rik ahl nmf181 nmf252 mdfw bob sals
Viability
Homozygous - Subviable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (36) Measurements chart (526) All data table (1088)
Expression & images (0) Disease models (0) Order (7)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating sodium level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.72×10-08
decreased circulating calcium level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.77×10-05
increased T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 8.00×10-07
decreased leukocyte cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 9.56×10-09
increased CD4-positive, alpha beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.49×10-05
impaired righting response Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 7.66×10-14
increased bone mineral content Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.04×10-07
increased alpha-beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 6.00×10-07
preweaning lethality, incomplete penetrance Cdh23tm2b(EUCOMM)Wtsi HOM n/a 0.00
decreased lean body mass Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.77×10-05
increased CD8-positive, alpha-beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
decreased body length Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.33×10-05
decreased fasted circulating glucose level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.64×10-15
increased NK cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
increased mean corpuscular volume Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 9.17×10-12
decreased Ly6C high monocyte number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 7.00×10-07
decreased mature B cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
decreased bone mineral content Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.23×10-05
decreased circulating triglyceride level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 5.46×10-05
abnormal gait Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.07×10-14
abnormal bone structure Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.73×10-09
decreased circulating insulin level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.64×10-06
decreased circulating glucose level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.33×10-07
decreased monocyte cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.49×10-05
decreased total body fat amount Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.77×10-11
decreased eosinophil cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
absent pinna reflex Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.56×10-18
trunk curl Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 3.60×10-19
increased lean body mass Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.71×10-09
decreased Ly6C low monocyte number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 6.00×10-07
increased circulating chloride level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.84×10-18
decreased B cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 1.39×10-05
stereotypic behavior Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 3.80×10-20
increased mean corpuscular hemoglobin Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 2.13×10-05
decreased circulating LDL cholesterol level Cdh23tm2b(EUCOMM)Wtsi HOM postnatal 4.08×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
Legacy Phenotype Associated Images
Cdh23v
body, HOM, Male, WTSI
Cdh23v
body, HOM, Male, WTSI
Cdh23v
HOM, Male, WTSI
Cdh23v
HOM, Male, WTSI
Cdh23v
body, HET, Male, WTSI

View all 181 images

Cdh23v
eye, cataracts, HOM, Male, WTSI
Cdh23v
eye, cataracts, HET, Female, WTSI
Cdh23v
eye, cataracts, HET, Female, WTSI

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cdh23em2H Point Mutation Mice
Cdh23em1H Point Mutation Mice
Cdh23tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cdh23tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cdh23em3(IMPC)H Point Mutation Mice
Cdh23tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cdh23tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells