Gene: Cdh23

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Name
cadherin 23 (otocadherin)
MGI ID
MGI:1890219
Synonyms
sals bob 4930542A03Rik nmf252 nmf181 nmf112 ahl USH1D mdfw
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (7)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
stereotypic behavior Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.64×10-20
increased T cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 6.00×10-07
increased NK cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 0.00
decreased leukocyte cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 8.11×10-09
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.35×10-05
impaired righting response Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 4.20×10-14
increased mean corpuscular hemoglobin Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 7.71×10-06
increased circulating LDL cholesterol level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 3.67×10-05
increased CD4-positive, alpha beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.53×10-05
decreased body length Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 2.10×10-05
increased lean body mass Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.95×10-08
decreased Ly6C low monocyte number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 5.00×10-07
decreased circulating calcium level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 4.96×10-05
increased circulating chloride level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 2.53×10-18
decreased B cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 0.00
decreased circulating LDL cholesterol level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 3.67×10-05
increased circulating sodium level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.97×10-08
decreased monocyte cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.53×10-05
preweaning lethality, incomplete penetrance Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 0.00
trunk curl Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.37×10-19
decreased circulating insulin level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 2.94×10-06
decreased circulating triglyceride level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 6.05×10-05
decreased eosinophil cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal gait Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.77×10-14
decreased bone mineral content Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 5.72×10-05
decreased total body fat amount Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.21×10-10
absent pinna reflex Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.97×10-18
decreased fasting circulating glucose level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 3.82×10-16
decreased circulating glucose level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.20×10-07
abnormal bone structure Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 3.99×10-09
decreased mature B cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 0.00
increased alpha-beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 7.00×10-07
decreased Ly6C high monocyte number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.53×10-05
increased bone mineral content Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 1.31×10-08
decreased circulating potassium level Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 6.83×10-05
increased CD8-positive, alpha-beta T cell number Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 0.00
decreased lean body mass Cdh23tm2b(EUCOMM)Wtsi HOM Early adult 4.45×10-06

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 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
Legacy Phenotype Associated Images

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 Disease Models

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MGI Allele Allele Type Produced
Cdh23em1H Point Mutation Mice
Cdh23tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cdh23tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Cdh23tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cdh23em3(IMPC)H Point Mutation Mice
Cdh23em2H Point Mutation Mice
Cdh23tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells