Gene: P3h1

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Name
prolyl 3-hydroxylase 1
MGI ID
MGI:1888921
Synonyms
2410024C15Rik Gros1 Lepre1 Leprecan
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal skin morphology P3h1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal skeletal muscle morphology P3h1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal heart morphology P3h1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased body length P3h1tm1b(EUCOMM)Wtsi HOM Early adult 6.21×10-07
decreased bone mineral density P3h1tm1b(EUCOMM)Wtsi HOM Early adult 4.52×10-12
enlarged heart P3h1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased grip strength P3h1tm1b(EUCOMM)Wtsi HOM Early adult 3.06×10-38
abnormal limb position P3h1tm1b(EUCOMM)Wtsi HOM Early adult 8.64×10-07
decreased heart rate P3h1tm1b(EUCOMM)Wtsi HOM Early adult 2.48×10-06
thin skin P3h1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased total body fat amount P3h1tm1b(EUCOMM)Wtsi HOM Early adult 1.58×10-06
decreased bone mineral content P3h1tm1b(EUCOMM)Wtsi HOM Early adult 7.64×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583)  (2/2)  Section images
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No  (1/2)  Section images
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407) N/A
Eye 2 No  (1/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (2/583) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No  (1/2)  Section images
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No  (2/583)  (1/2)  Section images
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (1/2)  Section images
Prostate gland 2 No  (12/583) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (1/2)  Section images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583)  (1/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/583) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/130) N/A
Testis 2 No  (6/583)  (1/2)  Section images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (3/583)  (1/2)  Section images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No N/A
Vas deferens 2 No  (15/382)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  Section images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
45 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
P3h1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
P3h1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
P3h1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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