Stau2 | staufen double-stranded RNA binding protein 2

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased hematocrit1 supporting datasetStau2em1(IMPC)MbphomozygoteEarly adult4.94x10-5 
increased hemoglobin content1 supporting datasetStau2em1(IMPC)MbphomozygoteEarly adult1.42x10-5 
increased total body fat amount2 supporting datasetsStau2tm1a(EUCOMM)WtsihomozygoteEarly adult1.19x10-5 
increased erythrocyte cell number1 supporting datasetStau2em1(IMPC)MbphomozygoteEarly adult2.18x10-5 
decreased lean body mass1 supporting datasetStau2tm1a(EUCOMM)WtsihomozygoteEarly adult2.8x10-5 
decreased body length1 supporting datasetStau2tm1a(EUCOMM)WtsihomozygoteEarly adult7.28x10-5 
hyperactivity1 supporting datasetStau2em1(IMPC)MbphomozygoteEarly adult9.37x10-5 
increased vertical activity1 supporting datasetStau2em1(IMPC)MbphomozygoteEarly adult2.48x10-5 
decreased bone mineral content2 supporting datasetsStau2tm1a(EUCOMM)WtsihomozygoteEarly adult5.92x10-5 
increased monocyte cell number2 supporting datasetsStau2em1(IMPC)MbphomozygoteEarly adult1.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Stau2em1(IMPC)MbpExon Deletionmouse
Stau2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Stau2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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