Genes Phenotypes

Gene: Mapkbp1

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Name
mitogen-activated protein kinase binding protein 1
MGI ID
MGI:1347004
Synonyms
Jnkbp1 2810483F24Rik
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (222) All data table (448)
Expression & images (67) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral content Mapkbp1tm1b(EUCOMM)Hmgu HOM Early adult 3.34×10-08
increased blood urea nitrogen level Mapkbp1tm1b(EUCOMM)Hmgu HOM Early adult 2.81×10-07
abnormal bone structure Mapkbp1tm1b(EUCOMM)Hmgu HOM Early adult 1.48×10-06
decreased bone mineral density Mapkbp1tm1b(EUCOMM)Hmgu HOM Early adult 3.12×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4)  Wholemount images
Aorta 4 No  (4/4) N/A
Bone 4 No N/A
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (4/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (4/4)  Wholemount images
Esophagus 4 No  (7/415)  (4/4)  Wholemount images
Eye 4 No  (4/4)  Wholemount images
Gall bladder 4 No  (3/4) N/A
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (4/4)  Wholemount images
Hypothalamus 4 No  (4/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No  Wholemount images
Lower urinary tract 4 No  (4/4)  Wholemount images
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No  (4/4)  Wholemount images
Oral epithelium 4 No  (3/4)  Wholemount images
Ovary 4 No  (1/584)  (2/4)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No  (4/4)  Wholemount images
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No  (4/4)  Wholemount images
Prostate gland 4 No  (12/584)  (2/4)  Wholemount images
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584)  (4/4)  Wholemount images
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No  (4/4)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No  (4/4)  Wholemount images
Uterus 4 No  (2/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (5)
Large Intestine expression
MA:0000333
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Prostate gland expression
Lower Urinary Tract expression
MA:0000404
MA:0002636
integumental system (1)
Skin expression
MA:0000151
nervous system (5)
Brain expression
Brainstem expression
Cerebellum expression
Cerebral Cortex expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000168
MA:0000169
MA:0000198
MA:0000185
MA:0000191
MA:0000173
MA:0002413
MA:0000891
postnatal mouse (24)
Adrenal gland expression
MA:0000116
reproductive system (4)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000385
MA:0000389
respiratory system (4)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (1)
Trachea expression
Parathyroid gland expression
Cartilage tissue expression
MA:0000441
MA:0000128
MA:0000104
trunk (15)
Adrenal gland expression
MA:0000116
urinary system (3)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3  (6/504)  (3/5) N/A
Ear 3  (1/504)  (2/5) N/A
Embryo 3  (1/505)  (5/5) N/A
Eye 3  (1/504)  (3/5) N/A
Foot 3  (1/504)  (1/5) N/A
Forebrain 3  (1/504)  (3/5) N/A
Forelimb 3  (1/504)  (2/5) N/A
Hand 3  (1/503)  (1/5) N/A
Head 3  (5/504)  (5/5) N/A
Heart 3  (1/504)  (2/5) N/A
Hindbrain 3  (6/504)  (3/5) N/A
Hindlimb 3  (1/503)  (2/5) N/A
Liver 3  (1/504)  (1/5) N/A
Lung 3  (1/500)  (1/5) N/A
Mandibular process 3  (1/504)  (2/5) N/A
Maxillary process 3  (1/504)  (2/5) N/A
Midbrain 3  (1/504)  (3/5) N/A
Oral cavity 3  (1/504)  (2/5) N/A
Skin 3  (1/504)  (2/5) N/A
Tail 3  (1/504)  (3/5) N/A
Tail somite 3  (1/504)  (1/5) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
24 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
19 Images
X-ray: XRay Images Whole Body Lateral Orientation
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Echo: M-Mode Images
28 Images
X-ray: XRay Images Hind Leg and Hip
2 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mapkbp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Mapkbp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Mapkbp1tm1c(EUCOMM)Hmgu Wild type floxed exon (post-Flp) Mice
Mapkbp1tm28155(L1L2_gt0) Targeting vectors

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