Gene: Parp1

Name
poly (ADP-ribose) polymerase family, member 1
MGI ID
MGI:1340806
Synonyms
PARP sPARP-1 Adprt1 parp-1 Adprp 5830444G22Rik
Viability
Homozygous - Subviable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased total retina thickness Parp1tm1b(EUCOMM)Hmgu HOM postnatal 1.23×10-08
abnormal retinal inner nuclear layer morphology Parp1tm1b(EUCOMM)Hmgu HOM postnatal 1.35×10-07
preweaning lethality, incomplete penetrance Parp1tm1b(EUCOMM)Hmgu HOM n/a 0.00
decreased grip strength Parp1tm1b(EUCOMM)Hmgu HOM postnatal 5.12×10-05

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Filtered by: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
12 Images
X-ray: XRay Images Lateral Orientation
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Parp1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Parp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors
Parp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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