Name
poly (ADP-ribose) polymerase family, member 1
MGI ID
MGI:1340806
Synonyms
PARP
sPARP-1
Adprp
parp-1
5830444G22Rik
Adprt1
Viability
Embryo viewer
N/A
Significant
Not Significant
Not tested
| Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
|---|---|---|---|---|---|---|
| decreased grip strength | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 1.92×10-05 | ||
| increased memory-marker CD4-negative NK T cell number | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 1.69×10-05 | ||
| abnormal retinal inner nuclear layer morphology | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 3.03×10-07 | ||
| immune system phenotype | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 7.50×10-06 | ||
| decreased lymphocyte cell number | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 5.92×10-05 | ||
| increased effector memory CD8-positive, alpha-beta T cell number | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 5.50×10-06 | ||
| decreased NK cell number | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 2.47×10-07 | ||
| decreased total retina thickness | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 7.12×10-07 | ||
| preweaning lethality, incomplete penetrance | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 0.00 | ||
| decreased leukocyte cell number | Parp1tm1b(EUCOMM)Hmgu | HOM | Early adult | 5.27×10-05 |
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