Parp1 | poly (ADP-ribose) polymerase family, member 1
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Vision/eye Nervous system Behavior/neurological Mortality/aging Reproductive system Immune system Homeostasis/metabolism Hematopoietic system Endocrine/exocrine gland Growth/size/body region
12 No significant impact
2 Not tested
Data collections
Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Parp1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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