Tmc6 | transmembrane channel-like gene family 6
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Skeleton Cardiovascular system
16 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
vertebral fusion | 1 supporting dataset | Tmc6tm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.02x10-5 | ||
decreased circulating cholesterol level | 1 supporting dataset | Tmc6tm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.8x10-5 | ||
decreased circulating serum albumin level | 1 supporting dataset | Tmc6tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.81x10-5 | ||
increased lean body mass | 1 supporting dataset | Tmc6tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.97x10-5 | ||
decreased circulating HDL cholesterol level | 1 supporting dataset | Tmc6tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.72x10-6 | ||
increased heart weight | 1 supporting dataset | Tmc6tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.53x10-5 |
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External links
No external links available for Tmc6.
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Tmc6tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |