Gene: Hnf4a

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Name
hepatic nuclear factor 4, alpha
MGI ID
MGI:109128
Synonyms
HNF-4 Nr2a1 Nuclear receptor 2A1 HNF4 alpha Tcf14 MODY1 Tcf4 Hnf4
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased prepulse inhibition Hnf4atm1b(EUCOMM)Hmgu HET   Early adult 7.31×10-05
increased circulating cholesterol level Hnf4atm1b(EUCOMM)Hmgu HET Early adult 7.56×10-05
abnormal lens morphology Hnf4atm1b(EUCOMM)Hmgu HET   Early adult 5.42×10-07
abnormal retinal blood vessel morphology Hnf4atm1b(EUCOMM)Hmgu HET Early adult 1.69×10-05
abnormal retinal vasculature morphology Hnf4atm1b(EUCOMM)Hmgu HET Early adult 5.77×10-06
enlarged thyroid gland Hnf4atm1b(EUCOMM)Hmgu HET Late adult 0.00
increased total retina thickness Hnf4atm1b(EUCOMM)Hmgu HET Early adult 1.02×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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MGI Allele Allele Type Produced
Hnf4atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Hnf4atm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Hnf4atm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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