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Gene: Bid MGI:108093

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
BH3 interacting domain death agonist
Synonyms:
2700049M22Rik

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Bid mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Bid by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Diabetes Insipidus, Neurohypophyseal
Gliosis OMIM:125700
Developmental And Epileptic Encephalopathy 71
Gliosis OMIM:618328
Immunodeficiency 83, Susceptibility To Viral Infections
Gliosis OMIM:613002
Developmental And Epileptic Encephalopathy 14
Gliosis OMIM:614959
L-2-Hydroxyglutaric Aciduria
Gliosis OMIM:236792
Huntington Disease
Gliosis OMIM:143100
Pontocerebellar Hypoplasia, Type 4
Gliosis OMIM:225753
Amyotrophic Lateral Sclerosis 15 With Or Without Frontotemporal Dementia
Gliosis OMIM:300857
Encephalopathy, Acute, Infection-Induced, Susceptibility To, 3
Gliosis, Pneumonia OMIM:608033
Pyruvate Dehydrogenase E1-Alpha Deficiency
Partial agenesis of the corpus callosum, Cerebellar gliosis, Lateral ventricle dilatation, Gliosi... ORPHA:79243
Congenital Neuronal Ceroid Lipofuscinosis
Abnormal astrocyte morphology, Agenesis of corpus callosum, Gliosis ORPHA:168486
Microcephaly 10, Primary, Autosomal Recessive
Agenesis of corpus callosum, Gliosis OMIM:615095
Mitochondrial Complex Iv Deficiency, Nuclear Type 6
Gliosis OMIM:615119
Pick Disease Of Brain
Gliosis OMIM:172700
Encephalopathy, Familial, With Neuroserpin Inclusion Bodies
Gliosis OMIM:604218
Mosaic Variegated Aneuploidy Syndrome 4
Abnormality of chromosome stability OMIM:620153
Primary Non-Essential Cutis Verticis Gyrata
Gliosis ORPHA:357225
Sporadic Creutzfeldt-Jakob Disease
Recurrent aspiration pneumonia, Gliosis, Astrocytosis ORPHA:204
Hemimegalencephaly
Gliosis ORPHA:99802
Adducted Thumbs Syndrome
Myelin-dependent gliosis OMIM:201550
Spinocerebellar Ataxia, Autosomal Recessive 2
Gliosis OMIM:213200
Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1
Gliosis OMIM:221820
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1
Lateral ventricle dilatation, Gliosis OMIM:221770
Neuropathy, Hereditary Motor And Sensory, Okinawa Type
Gliosis OMIM:604484
Lissencephaly, X-Linked, 2
Agenesis of corpus callosum, Gliosis OMIM:300215
Spinocerebellar Ataxia, Autosomal Recessive 27
Gliosis OMIM:618369
Leukoencephalopathy With Vanishing White Matter 1
Gliosis OMIM:603896
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1
Gliosis OMIM:105550
Cerebrooculofacioskeletal Syndrome 1
Recurrent pneumonia, Agenesis of corpus callosum, Gliosis OMIM:214150
Spinocerebellar Ataxia 17
Gliosis OMIM:607136
X-Linked Intellectual Disability-Short Stature-Overweight Syndrome
Gliosis, Pulmonary fibrosis ORPHA:457240
Duodenal Atresia
Abnormality of the pancreas, Annular pancreas, Abnormality of the pulmonary artery ORPHA:1203
Frontotemporal Dementia With Motor Neuron Disease
Gliosis ORPHA:275872
Spastic Paraplegia 50, Autosomal Recessive
Gliosis OMIM:612936
Spongiform Encephalopathy With Neuropsychiatric Features
Gliosis OMIM:606688
Leigh Syndrome
Gliosis OMIM:256000
Combined Oxidative Phosphorylation Deficiency 24
Agenesis of corpus callosum, Gliosis OMIM:616239
Huntington Disease-Like 1
Gliosis ORPHA:157941
Intellectual Developmental Disorder, X-Linked 12
Gliosis OMIM:300957
Rigidity And Multifocal Seizure Syndrome, Lethal Neonatal
Gliosis OMIM:614498
Mitochondrial Complex Iv Deficiency, Nuclear Type 2
Basal ganglia gliosis, Gliosis OMIM:604377
Neurodegeneration With Brain Iron Accumulation 2A
Gliosis OMIM:256600
Frontotemporal Lobar Degeneration With Tdp43 Inclusions, Grn-Related
Lateral ventricle dilatation, Gliosis OMIM:607485
Neurodegeneration, Childhood-Onset, With Progressive Microcephaly
Lateral ventricle dilatation, Gliosis OMIM:619847
Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant
Gliosis OMIM:169500
Pontocerebellar Hypoplasia, Type 2A
Gliosis OMIM:277470
Pancreatitis, Hereditary
Pancreatic calcification, Pancreatic pseudocyst, Pleural effusion, Pancreatitis, Exocrine pancrea... OMIM:167800
Combined Oxidative Phosphorylation Deficiency 14
Basal ganglia gliosis, Gliosis OMIM:614946
Familial Acute Necrotizing Encephalopathy
Gliosis ORPHA:88619
Multiple Acyl-Coa Dehydrogenase Deficiency
Gliosis, Pulmonary hypoplasia OMIM:231680
Machado-Joseph Disease
Gliosis OMIM:109150
Progressive Supranuclear Palsy
Gliosis ORPHA:683
Pelizaeus-Merzbacher Disease, Connatal Form
Gliosis ORPHA:280210
Kleefstra Syndrome Due To A Point Mutation
Gliosis ORPHA:261652
Central Nervous System Calcification-Deafness-Tubular Acidosis-Anemia Syndrome
Gliosis ORPHA:3240
Multiple Acyl-Coa Dehydrogenase Deficiency
Gliosis ORPHA:26791
Scleroderma, Familial Progressive
Chromosome breakage, Abnormality of chromosome stability OMIM:181750
Encephalopathy, Progressive, Early-Onset, With Brain Atrophy And Thin Corpus Callosum
Gliosis OMIM:617193
Leigh Syndrome
Agenesis of corpus callosum, Gliosis ORPHA:506
Parkinson Disease 1, Autosomal Dominant
Gliosis OMIM:168601
Mannosidosis, Alpha B, Lysosomal
Gliosis OMIM:248500
Encephalopathy, Progressive, Early-Onset, With Brain Edema And/Or Leukoencephalopathy, 2
Gliosis OMIM:618321
Tay-Sachs Disease
Gliosis, Aspiration pneumonia ORPHA:845
Papillorenal Syndrome
Gliosis OMIM:120330
Mitochondrial Complex I Deficiency, Nuclear Type 2
Gliosis OMIM:618222
Neurodevelopmental Disorder With Epilepsy And Hemochromatosis
Gliosis, Aspiration pneumonia OMIM:301072
Molybdenum Cofactor Deficiency, Complementation Group B
Gliosis OMIM:252160
Hereditary Late-Onset Parkinson Disease
Gliosis ORPHA:411602
Molybdenum Cofactor Deficiency, Complementation Group A
Gliosis OMIM:252150
D-Bifunctional Protein Deficiency
Gliosis OMIM:261515
Helsmoortel-Van Der Aa Syndrome
Recurrent respiratory infections, Lateral ventricle dilatation, Gliosis OMIM:615873
Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome 2
Lateral ventricle dilatation, Gliosis OMIM:300868
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Recurrent respiratory infections, Gliosis ORPHA:404454
Congenital Disorder Of Deglycosylation 1
Recurrent respiratory infections, Gliosis OMIM:615273
Cerebrotendinous Xanthomatosis
Abnormal lung morphology, Gliosis ORPHA:909
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type)
Gliosis, Astrocytosis OMIM:203700
Cutis Laxa, Autosomal Recessive, Type Iid
Pneumothorax, Gliosis OMIM:617403
Supranuclear Palsy, Progressive, 1
Gliosis, Astrocytosis OMIM:601104
Oxoglutaric Aciduria
Abnormality of Krebs cycle metabolism ORPHA:31
Dyrk1A-Related Intellectual Disability Syndrome Due To 21Q22.13Q22.2 Microdeletion
Gliosis ORPHA:268261
Gabriele-De Vries Syndrome
Agenesis of corpus callosum, Gliosis ORPHA:506358
Cockayne Syndrome
Gliosis ORPHA:191
Supranuclear Palsy, Progressive, 2
Gliosis OMIM:609454
Mitochondrial Complex Iv Deficiency, Nuclear Type 5
Partial agenesis of the corpus callosum, Gliosis, Pulmonary edema OMIM:220111
Diets-Jongmans Syndrome
Gliosis OMIM:618846
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Gliosis OMIM:124000

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Bid

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Bid.

No publications found that use IMPC mice or data for Bid.

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MGI Allele Allele Type Produced
Bidtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Bidtm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells

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