Gene: Hdac1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retinal vasculature morphology Hdac1tm1b(EUCOMM)Wtsi HET Early adult 2.34×10-07
abnormal lens morphology Hdac1tm1b(EUCOMM)Wtsi HET Early adult 5.29×10-06
preweaning lethality, complete penetrance Hdac1tm1b(EUCOMM)Wtsi HOM Early adult 1.79×10-08
abnormal retinal blood vessel morphology Hdac1tm1b(EUCOMM)Wtsi HET Early adult 1.25×10-06
cataract Hdac1tm1b(EUCOMM)Wtsi HET Early adult 3.26×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (1/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (1/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (1/2) N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No  (1/2) N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Section Images

View all 19 images

View all 13 images

No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
Legacy Phenotype Associated Images

View all 196 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hdac1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Hdac1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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