Rgl1 | ral guanine nucleotide dissociation stimulator,-like 1
Physiological systems
22 / 24 physiological systems tested
16 Significantly impacted by the knock-out
Reproductive system Immune system Growth/size/body region Digestive/alimentary Hematopoietic system Craniofacial Cardiovascular system Renal/urinary system Homeostasis/metabolism Embryo Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Behavior/neurological Mortality/aging
6 No significant impact
2 Not tested
Data collections
Gene metrics:32Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
enlarged spleen | 2 supporting datasets | Rgl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
cleft palate | 1 supporting dataset | Rgl1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
small liver | 2 supporting datasets | Rgl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
decreased prepulse inhibition | 2 supporting datasets | Rgl1em1(IMPC)Mbp | heterozygote | Early adult | 5.09x10-7 | ||
enlarged lymph nodes | 2 supporting datasets | Rgl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal lymph node morphology | 2 supporting datasets | Rgl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal midbrain development | 1 supporting dataset | Rgl1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Rgl1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
increased neutrophil cell number | 2 supporting datasets | Rgl1em1(IMPC)Mbp | heterozygote | Early adult | 3.04x10-6 | ||
edema | 1 supporting dataset | Rgl1em1(IMPC)Mbp | homozygote | E15.5 | N/A * |
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External links
No external links available for Rgl1.
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Rgl1em1(IMPC)Mbp | Exon Deletion | | mouse |
Rgl1tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Rgl1tm1e(KOMP)Mbp | Targeted, non-conditional allele | | es cell |
Rgl1tm2a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Rgl1tm2e(KOMP)Mbp | Targeted, non-conditional allele | | es cell |
Rgl1tm41618(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |