Genes Phenotypes

Gene: Lyst

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Name
lysosomal trafficking regulator
MGI ID
MGI:107448
Synonyms
D13Sfk13
Viability
N/A
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (222) All data table (326)
Expression & images (0) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular volume Lysttm1b(EUCOMM)Wtsi HOM postnatal 2.17×10-05
decreased body length Lysttm1b(EUCOMM)Wtsi HOM postnatal 6.92×10-05
increased lymphocyte cell number Lysttm1b(EUCOMM)Wtsi HOM postnatal 1.40×10-05
abnormal coat/hair pigmentation Lysttm1b(EUCOMM)Wtsi HOM postnatal 2.38×10-21
abnormal retina morphology Lysttm1b(EUCOMM)Wtsi HOM postnatal 2.89×10-10
increased fasted circulating glucose level Lysttm1b(EUCOMM)Wtsi HOM postnatal 3.52×10-05
abnormal iris morphology Lysttm1b(EUCOMM)Wtsi HOM postnatal 3.62×10-16

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 Expression

Expression data not available

 Associated Images

Eye Morphology: Images Slit Lamp
11 Images
Eye Morphology: Images Ophthalmoscopy
14 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
Histopathology
2 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Combined SHIRPA and Dysmorphology
17 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental dysplasia Lysttm1b(EUCOMM)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Lysttm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Lysttm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue