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Genes Phenotypes

Gene: Lyst

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Name
lysosomal trafficking regulator
MGI ID
MGI:107448
Synonyms
D13Sfk13
Viability
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (185) All data table (488)
Expression & images (0) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal iris morphology Lysttm1b(EUCOMM)Wtsi HOM Early adult 1.45×10-13
increased mean corpuscular volume Lysttm1b(EUCOMM)Wtsi HOM Early adult 4.15×10-05
increased fasting circulating glucose level Lysttm1b(EUCOMM)Wtsi HOM   Early adult 2.79×10-05
decreased neutrophil cell number Lysttm1b(EUCOMM)Wtsi HOM Early adult 4.15×10-06
abnormal coat/hair pigmentation Lysttm1b(EUCOMM)Wtsi HOM Early adult 1.22×10-21
abnormal retina morphology Lysttm1b(EUCOMM)Wtsi HOM Early adult 8.01×10-11
increased lymphocyte cell number Lysttm1b(EUCOMM)Wtsi HOM Early adult 1.01×10-05

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 Expression

Expression data not available

 Associated Images

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Combined SHIRPA and Dysmorphology
17 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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Eye Morphology: Images Ophthalmoscopy
14 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Gross Pathology and Tissue Collection
8 Images
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Eye Morphology: Images Slit Lamp
11 Images
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Histopathology
2 Images
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X-ray: XRay Images Skull Lateral Orientation
10 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental dysplasia Lysttm1b(EUCOMM)Wtsi HOM Early adult

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MGI Allele Allele Type Produced
Lysttm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Lysttm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells