Gene: Lyst

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Name
lysosomal trafficking regulator
MGI ID
MGI:107448
Synonyms
D13Sfk13
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal iris morphology Lysttm1b(EUCOMM)Wtsi HOM Early adult 1.06×10-16
increased mean corpuscular volume Lysttm1b(EUCOMM)Wtsi HOM Early adult 1.94×10-05
increased fasting circulating glucose level Lysttm1b(EUCOMM)Wtsi HOM Early adult 1.99×10-05
abnormal coat/hair pigmentation Lysttm1b(EUCOMM)Wtsi HOM Early adult 2.95×10-22
increased lymphocyte cell number Lysttm1b(EUCOMM)Wtsi HOM Early adult 3.77×10-05
decreased body length Lysttm1b(EUCOMM)Wtsi HOM Early adult 6.92×10-05

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 Expression

Expression data not available

 Associated Images

Combined SHIRPA and Dysmorphology
17 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Slit Lamp
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
14 Images
Histopathology
2 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental dysplasia Lysttm1b(EUCOMM)Wtsi HOM Early adult

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MGI Allele Allele Type Produced
Lysttm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Lysttm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue