Genes Phenotypes

Gene: Pitx1

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Name
paired-like homeodomain transcription factor 1
MGI ID
MGI:107374
Synonyms
Ptx1 Potx P-OTX Bft
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (9) Measurements chart (332) All data table (485)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased bone mineral content Pitx1em1(IMPC)Wtsi HET postnatal 3.86×10-06
preweaning lethality, complete penetrance Pitx1em1(IMPC)Wtsi HOM n/a 0.00
decreased bone mineral content Pitx1em1(IMPC)Wtsi HET postnatal 6.20×10-05
abnormal digit morphology Pitx1em1(IMPC)Wtsi HET postnatal 1.83×10-08
fused phalanges Pitx1em1(IMPC)Wtsi HET postnatal 6.20×10-05
abnormal bone structure Pitx1em1(IMPC)Wtsi HET postnatal 5.33×10-05
decreased circulating insulin level Pitx1em1(IMPC)Wtsi HET postnatal 5.96×10-05
abnormal nail morphology Pitx1em1(IMPC)Wtsi HET postnatal 1.66×10-05
abnormal autopod morphology Pitx1em1(IMPC)Wtsi HET postnatal 6.20×10-05

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 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
Anti-nuclear antibody assay
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Pitx1tm208889(L1L2_Bact_P) Targeting vectors
Pitx1em1(IMPC)Wtsi Exdel Mice