Slx4 - SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | International Mouse Phenotyping Consortium

Genes Phenotypes

Gene: Slx4

Name

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

MGI ID

MGI:106299

Synonyms

D16Bwg1016e Btbd12

Viability

Homozygous - Subviable

Embryo Screen

N/A

Other links

MGI Ensembl

Expression & images (45) Disease models (0) Order (1)

Significant

Not Significant

Not tested

Phenotype	Allele	Zyg	Life Stage	P Value
corneal opacity	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	7.16×10^-06
abnormal eyelid aperture	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	9.84×10^-05
abnormal eye size	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	3.27×10^-07
preweaning lethality, incomplete penetrance	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	n/a	0.00
abnormal cranium morphology	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	8.53×10^-06
increased bone mineral density	Slx4^{tm1a(EUCOMM)Wtsi}	HET	postnatal	4.11×10^-05
abnormal cornea morphology	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	3.26×10^-07
vertebral fusion	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	1.00×10^-05
abnormal placement of pupils	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	1.02×10^-05
abnormal eye morphology	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	4.88×10^-05
abnormal iris morphology	Slx4^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	6.12×10^-05

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Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	3	No	(2/584)		N/A
Aorta	3	No			N/A
Blood vessel	3	No			N/A
Bone	3	No			N/A
Brain	3	No		(3/3)	N/A
Brainstem	3	No			N/A
Brown adipose tissue	3	No			N/A
Cartilage tissue	3	No		(2/3)	N/A
Cerebellum	3	No			N/A
Cerebral cortex	3	No			N/A
Eye	3	No			N/A
Gall bladder	3	No			N/A
Heart	3	No			N/A
Hippocampus	3	No			N/A
Hypothalamus	3	No			N/A
Kidney	3	No	(18/584)	(1/3)	N/A
Large intestine	3	No	(10/584)		N/A
Liver	3	No			N/A
Lower urinary tract	3	No			N/A
Lung	3	No			N/A
Lymph node	3	No			N/A
Mammary gland	3	No			N/A
Esophagus	3	No			N/A
Olfactory lobe	3	No			N/A
Ovary	3	No	(1/584)		N/A
Oviduct	3	No			N/A
Pancreas	3	No	(5/584)		N/A
Parathyroid gland	3	No			N/A
Peripheral nervous system	3	No		(3/3)	N/A
Peyer's patch	3	No			N/A
Pituitary gland	3	No			N/A
Prostate gland	3	No	(12/584)		N/A
Skeletal muscle tissue	3	No			N/A
Skin	3	No			N/A
Small intestine	3	No	(9/584)		N/A
Spinal cord	3	No		(3/3)	N/A
Spleen	3	No	(2/584)		N/A
Stomach	3	No	(12/584)		N/A
Striatum	3	No			N/A
Testis	3	No	(2/584)	(1/3)	N/A
Thymus	3	No			N/A
Thyroid gland	3	No	(15/584)		N/A
Trachea	3	No		(2/3)	N/A
Uterus	3	No			N/A
White adipose tissue	3	No			N/A