Gene: Slx4

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SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Btbd12 D16Bwg1016e
Embryo viewer
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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased bone mineral density Slx4tm1a(EUCOMM)Wtsi HET Early adult 7.16×10-08
corneal opacity Slx4tm1a(EUCOMM)Wtsi HOM Early adult 9.54×10-06
anophthalmia Slx4tm1a(EUCOMM)Wtsi HOM Early adult 9.05×10-05
abnormal eyelid aperture Slx4tm1a(EUCOMM)Wtsi HOM Early adult 1.55×10-06
abnormal cornea morphology Slx4tm1a(EUCOMM)Wtsi HOM Early adult 2.91×10-08
abnormal placement of pupils Slx4tm1a(EUCOMM)Wtsi HOM Early adult 7.16×10-05
abnormal iris morphology Slx4tm1a(EUCOMM)Wtsi HOM Early adult 1.49×10-05
abnormal eye morphology Slx4tm1a(EUCOMM)Wtsi HOM Early adult 2.78×10-05
abnormal eye size Slx4tm1a(EUCOMM)Wtsi HOM Early adult 6.57×10-08
impaired pupillary reflex Slx4tm1a(EUCOMM)Wtsi HOM Early adult 4.68×10-05
decreased body weight Slx4tm1a(EUCOMM)Wtsi HET Early adult 1.37×10-05

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Select physiological systems to view:
Viewing: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584) N/A
Aorta 3 No N/A
Blood vessel 3 No N/A
Bone 3 No N/A
Brain 3 No  (3/3) N/A
Brainstem 3 No N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No  (2/3) N/A
Cerebellum 3 No N/A
Cerebral cortex 3 No N/A
Eye 3 No N/A
Gall bladder 3 No N/A
Heart 3 No N/A
Hippocampus 3 No N/A
Hypothalamus 3 No N/A
Kidney 3 No  (18/584)  (1/3) N/A
Large intestine 3 No  (10/584) N/A
Liver 3 No N/A
Lower urinary tract 3 No N/A
Lung 3 No N/A
Lymph node 3 No N/A
Mammary gland 3 No N/A
Esophagus 3 No N/A
Olfactory lobe 3 No N/A
Ovary 3 No  (1/584) N/A
Oviduct 3 No N/A
Pancreas 3 No  (5/584) N/A
Parathyroid gland 3 No N/A
Peripheral nervous system 3 No  (3/3) N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No N/A
Prostate gland 3 No  (12/584) N/A
Skeletal muscle tissue 3 No N/A
Skin 3 No N/A
Small intestine 3 No  (9/584) N/A
Spinal cord 3 No  (3/3) N/A
Spleen 3 No  (2/584) N/A
Stomach 3 No  (12/584) N/A
Striatum 3 No N/A
Testis 3 No  (2/584)  (1/3) N/A
Thymus 3 No N/A
Thyroid gland 3 No  (15/584) N/A
Trachea 3 No  (2/3) N/A
Uterus 3 No N/A
White adipose tissue 3 No N/A
LacZ Section Images

View all 23 images

View all 12 images

No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images

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View all 9 images

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View all 6 images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slx4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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