Runx1t1 | RUNX1 translocation partner 1

GeneMGI:104793Synonyms: MTG8, Cbfa2t1h, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetRunx1t1tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased circulating triglyceride level1 supporting datasetRunx1t1tm1b(EUCOMM)HmguheterozygoteEarly adult1.48x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Runx1t1tm171(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Runx1t1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Runx1t1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Runx1t1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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