Nrcam | neuronal cell adhesion molecule
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Behavior/neurological
14 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
26Embryo tissues
limb grasping | 1 supporting dataset | Nrcamtm2e.1(KOMP)Wtsi | heterozygote | Early adult | 5.45x10-5 | ||
convulsive seizures | 1 supporting dataset | Nrcamtm2e.1(KOMP)Wtsi | homozygote | Early adult | 7.49x10-5 | ||
increased fasting circulating glucose level | 1 supporting dataset | Nrcamtm2e.1(KOMP)Wtsi | heterozygote | Early adult | 3.38x10-6 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
epididymis | heterozygote | n/a | 0% (0/1) | 87.5% (21/24) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Nrcam.
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Nrcamtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Nrcamtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
Nrcamtm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Nrcamtm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell mouse |
Nrcamtm2e.1(KOMP)Wtsi | Promoter excision from Targeted, non-conditional allele | | mouse |