Genes Phenotypes

Gene: Col4a3

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Name
collagen, type IV, alpha 3
MGI ID
MGI:104688
Synonyms
tumstatin alpha3(IV)
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (243) All data table (385)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating bilirubin level Col4a3tm1b(EUCOMM)Wtsi HOM postnatal 6.43×10-05
decreased circulating amylase level Col4a3tm1b(EUCOMM)Wtsi HOM postnatal 7.31×10-07
irregularly shaped pupil Col4a3tm1b(EUCOMM)Wtsi HOM postnatal 1.72×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
Aorta expression
MA:0000072
MA:0000062
digestive system (1)
Stomach expression
MA:0000353
endocrine system (1)
Cartilage tissue expression
Thyroid gland expression
Trachea expression
MA:0000104
MA:0000129
MA:0000441
exocrine system (1)
Prostate gland expression
MA:0000404
postnatal mouse (10)
Cartilage tissue expression
MA:0000104
reproductive system (3)
Oviduct expression
MA:0000385
respiratory system (1)
Cartilage tissue expression
Thyroid gland expression
Trachea expression
MA:0000104
MA:0000129
MA:0000441
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
MA:0000104
trunk (8)
Cartilage tissue expression
Thyroid gland expression
Trachea expression
MA:0000104
MA:0000129
MA:0000441
urinary system (1)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Echo: M-Mode Images
32 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Adult LacZ: LacZ Images Wholemount
10 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Col4a3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Col4a3tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice
Col4a3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice