Col4a3 | collagen, type IV, alpha 3
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system
14 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
7Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
decreased basophil cell number | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.98x10-5 | ||
decreased hemoglobin content | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.24x10-8 | ||
increased neutrophil cell number | 2 supporting datasets | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.09x10-8 | ||
decreased lymphocyte cell number | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.88x10-8 | ||
increased kidney weight | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.46x10-18 | ||
increased large unstained cell number | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.12x10-5 | ||
decreased circulating amylase level | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.33x10-5 | ||
irregularly shaped pupil | 1 supporting dataset | Col4a3tm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.4x10-6 |
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External links
No external links available for Col4a3.
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Col4a3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Col4a3tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Col4a3tm1c(EUCOMM)Wtsi | Wild type floxed exon (post-Flp) | | mouse |
Col4a3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |