Gene: Ap2a2

Log in to follow

Name
adaptor-related protein complex 2, alpha 2 subunit
MGI ID
MGI:101920
Synonyms
alpha-C adaptin Adtab alpha-adaptin C L25 2410074K14Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating cholesterol level Ap2a2em1(IMPC)Wtsi HET Early adult 3.35×10-05
absent pinna reflex Ap2a2tm1b(EUCOMM)Wtsi HOM Early adult 1.25×10-09
increased circulating LDL cholesterol level Ap2a2em1(IMPC)Wtsi HET Early adult 1.73×10-08
preweaning lethality, incomplete penetrance Ap2a2em1(IMPC)Wtsi HOM Early adult 0.00
increased circulating HDL cholesterol level Ap2a2em1(IMPC)Wtsi HET Early adult 4.88×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Blood vessel 2 No N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (1/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Section Images

View all 22 images

View all 15 images

No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
65 Images
X-ray: XRay Images Whole Body Dorso Ventral
85 Images
X-ray: XRay Images Forepaw
33 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
32 Images
X-ray: XRay Images Skull Lateral Orientation
32 Images
DSS Histology
12 Images
Eye Morphology: Images Slit Lamp
1 Images
Anti-nuclear antibody assay
6 Images
Legacy Phenotype Associated Images

View all 165 images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Ap2a2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ap2a2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Ap2a2em1(IMPC)Wtsi Exdel Mice
Ap2a2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter