Phenotype: abnormal CD4-negative, CD25-positive NK T cell number

Definition
anomaly in the number of CD4-negative NK T cells expressing the activation marker CD25
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal CD4-negative, CD25-positive NK T cell number

Total number of significant genotype-phenotype associations: 2

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Lgr5
Lgr5em1(IMPC)Kmpc
HET   Early adult increased CD4-negative, CD25-positive NK T cell number DN CD25+ NKT cells
Immunophenotyping
KMPC
IMPC
5.38×10-05
Pip4p1
Pip4p1em1(IMPC)Ccpcz
HOM   Early adult increased CD4-negative, CD25-positive NK T cell number DN CD25+ NKT cells
Immunophenotyping
CCP-IMG
IMPC
8.23×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

2.82% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal CD4-negative, CD25-positive NK T cell number (2/71)

0.00% females (0/66) 0.00% males (0/65)

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